Steroid 11-beta-Hydroxylase
"Steroid 11-beta-Hydroxylase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mitochondrial cytochrome P450 enzyme that catalyzes the 11-beta-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP11B1 gene, is important in the synthesis of CORTICOSTERONE and HYDROCORTISONE. Defects in CYP11B1 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL).
| Descriptor ID |
D013252
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| MeSH Number(s) |
D08.244.453.484.750 D08.244.453.915.750 D08.811.682.690.708.170.425.750 D08.811.682.690.708.170.915.750 D12.776.422.220.453.484.750 D12.776.422.220.453.915.750
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| Concept/Terms |
Steroid 11-beta-Hydroxylase- Steroid 11-beta-Hydroxylase
- Steroid 11 beta Hydroxylase
- Cytochrome P-450(11 beta)
- Steroid 11 Hydroxylase
- Steroid-11-Hydroxylase
- Cytochrome P-450 CYP11B1
- Cytochrome P 450 CYP11B1
- CYP11B1
- Steroid 11-beta-Monooxygenase
- Steroid 11 beta Monooxygenase
- CYP 11B1
- Cytochrome P450 11B1
- 11 beta-Hydroxylase
- 11 beta Hydroxylase
- Steroid 11-Hydroxylase
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Below are MeSH descriptors whose meaning is more general than "Steroid 11-beta-Hydroxylase".
Below are MeSH descriptors whose meaning is more specific than "Steroid 11-beta-Hydroxylase".
This graph shows the total number of publications written about "Steroid 11-beta-Hydroxylase" by people in this website by year, and whether "Steroid 11-beta-Hydroxylase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 2 | 2 |
| 2003 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
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Below are the most recent publications written about "Steroid 11-beta-Hydroxylase" by people in Profiles.
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Update on the prenatal diagnosis and treatment of congenital adrenal hyperplasia due to 11beta-hydroxylase deficiency. J Pediatr Endocrinol Metab. 2005 Feb; 18(2):133-42.
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Hypertension and adrenal disorders. Curr Hypertens Rep. 2003 Dec; 5(6):498-504.
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Prenatal diagnosis and treatment of 11beta-hydroxylase deficiency congenital adrenal hyperplasia resulting in normal female genitalia. J Clin Endocrinol Metab. 1999 Sep; 84(9):3129-34.
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Congenital adrenal hyperplasia (21-hydroxylase deficiency) without demonstrable genetic mutations. J Clin Endocrinol Metab. 1999 Jan; 84(1):378-81.