"Aromatase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the desaturation (aromatization) of the ring A of C19 androgens and converts them to C18 estrogens. In this process, the 19-methyl is removed. This enzyme is membrane-bound, located in the endoplasmic reticulum of estrogen-producing cells of ovaries, placenta, testes, adipose, and brain tissues. Aromatase is encoded by the CYP19 gene, and functions in complex with NADPH-FERRIHEMOPROTEIN REDUCTASE in the cytochrome P-450 system.
| Descriptor ID |
D001141
|
| MeSH Number(s) |
D08.244.453.489.500 D08.244.453.915.099 D08.811.682.690.708.170.447.500 D08.811.682.690.708.170.915.099 D12.776.422.220.453.489.500 D12.776.422.220.453.915.099
|
| Concept/Terms |
Aromatase- Aromatase
- Estrogen Synthetase
- Estrogen Synthase
- Cytochrome P450 19
- CYP19 Protein
- Protein, CYP19
- Cytochrome P-450(AROM)
- CYP 19
- Cytochrome P-450 CYP19
- Cytochrome P 450 CYP19
- P450AROM
- Androstenedione Aromatase
- Aromatase, Androstenedione
- CYP19
|
Below are MeSH descriptors whose meaning is more general than "Aromatase".
Below are MeSH descriptors whose meaning is more specific than "Aromatase".
This graph shows the total number of publications written about "Aromatase" by people in this website by year, and whether "Aromatase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 2 | 0 | 2 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Aromatase" by people in Profiles.
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Sex-specific regulation of stress-induced fetal glucocorticoid surge by the mouse placenta. Am J Physiol Endocrinol Metab. 2019 07 01; 317(1):E109-E120.
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Incubation history prior to the canonical thermosensitive period determines sex in the American alligator. Reproduction. 2015 Oct; 150(4):279-87.
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Differential incubation temperatures result in dimorphic DNA methylation patterning of the SOX9 and aromatase promoters in gonads of alligator (Alligator mississippiensis) embryos. Biol Reprod. 2014 Jan; 90(1):2.
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Impact of aromatase genetic variation on hormone levels and global outcome after severe TBI. J Neurotrauma. 2013 Aug 15; 30(16):1415-25.
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PPAR? agonists target aromatase via both PGE2 and BRCA1. Cancer Prev Res (Phila). 2012 Oct; 5(10):1169-72.
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The role of the PGE2-aromatase pathway in obesity-associated breast inflammation. Cancer Discov. 2012 Apr; 2(4):308-10.
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Aromatase inhibition causes increased amplitude, but not frequency, of hypothalamic-pituitary output in normal women. Fertil Steril. 2011 May; 95(6):2063-6.
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Expression of Cre recombinase in early diploid trophoblast cells of the mouse placenta. Genesis. 2007 Mar; 45(3):129-34.