Endothelin Receptor Antagonists
"Endothelin Receptor Antagonists" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds and drugs that bind to and inhibit or block the activation of ENDOTHELIN RECECPTORS.
| Descriptor ID |
D065128
|
| MeSH Number(s) |
D27.505.519.364
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Endothelin Receptor Antagonists".
Below are MeSH descriptors whose meaning is more specific than "Endothelin Receptor Antagonists".
This graph shows the total number of publications written about "Endothelin Receptor Antagonists" by people in this website by year, and whether "Endothelin Receptor Antagonists" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 2 | 2 |
| 1998 | 1 | 1 | 2 |
| 2001 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
| 2003 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2010 | 1 | 1 | 2 |
| 2014 | 2 | 0 | 2 |
| 2016 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Endothelin Receptor Antagonists" by people in Profiles.
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Lipopolysaccharide-induced necroptosis of brain microvascular endothelial cells can be prevented by inhibition of endothelin receptors. Physiol Res. 2018 06 27; 67(Suppl 1):S227-S236.
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Update of EULAR recommendations for the treatment of systemic sclerosis. Ann Rheum Dis. 2017 Aug; 76(8):1327-1339.
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Randomized, double-blind, placebo-controlled study of sitaxsentan to improve impaired exercise tolerance in patients with heart failure and a preserved ejection fraction. JACC Heart Fail. 2014 Apr; 2(2):123-30.
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Dual endothelin receptor antagonism with bosentan reverses established vascular remodeling and dysfunctional angiogenesis in diabetic rats: relevance to glycemic control. Life Sci. 2014 Nov 24; 118(2):268-73.
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Endothelial endothelin B receptor-mediated prevention of cerebrovascular remodeling is attenuated in diabetes because of up-regulation of smooth muscle endothelin receptors. J Pharmacol Exp Ther. 2011 Apr; 337(1):9-15.
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Dual endothelin receptor antagonism prevents remodeling of resistance arteries in diabetes. Can J Physiol Pharmacol. 2010 Jun; 88(6):616-21.
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Endothelin and scleroderma lung disease. Rheumatology (Oxford). 2008 Oct; 47 Suppl 5:v25-6.
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Type-2 diabetes-induced changes in vascular extracellular matrix gene expression: relation to vessel size. Cardiovasc Diabetol. 2006 Feb 17; 5:3.
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RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain. Nat Med. 2003 Jul; 9(7):907-13.
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Endothelin-1 and endothelin receptor antagonists as potential cardiovascular therapeutic agents. Pharmacotherapy. 2002 Jan; 22(1):54-65.