"ELAV-Like Protein 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An RRM protein that binds to the 3'-UTR region of mRNAs and increases their stability. In EMBRYONIC STEM CELLS, it binds to poly-U elements and AU-rich elements (AREs) in the 3'-UTR of target mRNAs and preferentially binds mRNAs that are not methylated by N6-methyladenosine (m6A), to stabilize them and promote differentiation.
| Descriptor ID |
D000067780
|
| MeSH Number(s) |
D12.776.157.725.813.500.250 D12.776.664.962.813.500.250
|
| Concept/Terms |
ELAV-Like Protein 1- ELAV-Like Protein 1
- ELAV Like Protein 1
- HuR Paraneoplastic Encephalomyelitis Antigen
- HuR Protein
- Protein, HuR
- ELAVL1 protein
- protein, ELAVL1
- HuR Antigen
- Antigen, HuR
|
Below are MeSH descriptors whose meaning is more general than "ELAV-Like Protein 1".
Below are MeSH descriptors whose meaning is more specific than "ELAV-Like Protein 1".
This graph shows the total number of publications written about "ELAV-Like Protein 1" by people in this website by year, and whether "ELAV-Like Protein 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 2 | 2 |
| 2010 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "ELAV-Like Protein 1" by people in Profiles.
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HuR as a molecular target for cancer therapeutics and immune-related disorders. Adv Drug Deliv Rev. 2022 09; 188:114442.
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Smoking-induced control of miR-133a-3p alters the expression of EGFR and HuR in HPV-infected oropharyngeal cancer. PLoS One. 2018; 13(10):e0205077.
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Regulation of nucleolin expression by miR-194, miR-206, and HuR. Mol Cell Biochem. 2016 Jun; 417(1-2):141-53.
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PAR-CLIP analysis uncovers AUF1 impact on target RNA fate and genome integrity. Nat Commun. 2014 Nov 04; 5:5248.
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Novel mechanisms in the regulation of G protein-coupled receptor trafficking to the plasma membrane. J Biol Chem. 2010 Oct 29; 285(44):33816-25.
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Regulation of Bcl-2 expression by HuR in HL60 leukemia cells and A431 carcinoma cells. Mol Cancer Res. 2009 Aug; 7(8):1354-66.
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The mRNA binding proteins HuR and tristetraprolin regulate cyclooxygenase 2 expression during colon carcinogenesis. Gastroenterology. 2009 May; 136(5):1669-79.