"APOBEC Deaminases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of conserved cytidine deaminases that catalyze the DEAMINATION of CYTIDINE to URIDINE. They are characterized by N and C-terminal zinc-dependent catalytic domains and have important functions in RNA EDITING; EPIGENTIC PROCESSES; and the INNATE IMMUNE RESPONSE against viruses.
| Descriptor ID |
D000071478
|
| MeSH Number(s) |
D08.811.277.151.486.250.500
|
| Concept/Terms |
APOBEC Deaminases- APOBEC Deaminases
- Deaminases, APOBEC
- APOBEC Family Proteins
- APOBEC Enzymes
- Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptides
- AID-APOBEC Deaminases
- AID APOBEC Deaminases
- Deaminases, AID-APOBEC
|
Below are MeSH descriptors whose meaning is more general than "APOBEC Deaminases".
Below are MeSH descriptors whose meaning is more specific than "APOBEC Deaminases".
This graph shows the total number of publications written about "APOBEC Deaminases" by people in this website by year, and whether "APOBEC Deaminases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "APOBEC Deaminases" by people in Profiles.
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Conformational Dynamics of the HIV-Vif Protein Complex. Biophys J. 2019 04 23; 116(8):1432-1445.
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Fab-based inhibitors reveal ubiquitin independent functions for HIV Vif neutralization of APOBEC3 restriction factors. PLoS Pathog. 2018 01; 14(1):e1006830.
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Lineage-Specific Viral Hijacking of Non-canonical E3?Ubiquitin Ligase Cofactors in the Evolution of Vif Anti-APOBEC3 Activity. Cell Rep. 2015 May 26; 11(8):1236-50.
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CBF? stabilizes HIV Vif to counteract APOBEC3 at the expense of RUNX1 target gene expression. Mol Cell. 2013 Feb 21; 49(4):632-44.