"Agouti-Related Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A secreted protein of approximately 131 amino acids that is related to AGOUTI SIGNALING PROTEIN and is also an antagonist of MELANOCORTIN RECEPTOR activity. It is expressed primarily in the HYPOTHALAMUS and the ADRENAL GLAND. As a paracrine signaling molecule, AGRP is known to regulate food intake and body weight. Elevated AGRP has been associated with OBESITY.
| Descriptor ID |
D054369
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| MeSH Number(s) |
D12.644.276.074 D12.776.467.074 D23.529.074
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Agouti-Related Protein".
Below are MeSH descriptors whose meaning is more specific than "Agouti-Related Protein".
This graph shows the total number of publications written about "Agouti-Related Protein" by people in this website by year, and whether "Agouti-Related Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
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Below are the most recent publications written about "Agouti-Related Protein" by people in Profiles.
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A role for the Agouti-Related Protein promoter in obesity and type 2 diabetes. Biochem Biophys Res Commun. 2001 Sep 21; 287(2):568-73.