E2F4 Transcription Factor
"E2F4 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An E2F transcription factor that represses GENETIC TRANSCRIPTION required for CELL CYCLE entry and DNA synthesis. E2F4 recruits chromatin remodeling factors indirectly to target gene PROMOTER REGIONS through RETINOBLASTOMA LIKE PROTEIN P130 and RETINOBLASTOMA LIKE PROTEIN P107.
| Descriptor ID |
D050704
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| MeSH Number(s) |
D12.776.930.211.812
|
| Concept/Terms |
E2F4 Transcription Factor- E2F4 Transcription Factor
- Transcription Factor, E2F4
- E2F-4 Transcription Factor
- E2F 4 Transcription Factor
- Transcription Factor, E2F-4
- E2F Transcription Factor 4 Protein
- E2F-4 Protein
- E2F 4 Protein
- Transcription Factor E2F-4
- E2F-4, Transcription Factor
- Transcription Factor E2F 4
|
Below are MeSH descriptors whose meaning is more general than "E2F4 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "E2F4 Transcription Factor".
This graph shows the total number of publications written about "E2F4 Transcription Factor" by people in this website by year, and whether "E2F4 Transcription Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "E2F4 Transcription Factor" by people in Profiles.
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Two Distinct E2F Transcriptional Modules Drive Cell Cycles and Differentiation. Cell Rep. 2019 06 18; 27(12):3547-3560.e5.
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E2F3 is a mediator of DNA damage-induced apoptosis. Mol Cell Biol. 2010 Jan; 30(2):524-36.
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Intestinal hyperplasia induced by simian virus 40 large tumor antigen requires E2F2. J Virol. 2007 Dec; 81(23):13191-9.
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Cloning and characterization of mouse E2F8, a novel mammalian E2F family member capable of blocking cellular proliferation. J Biol Chem. 2005 May 06; 280(18):18211-20.
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Distinct capacities of individual E2Fs to induce cell cycle re-entry in postmitotic lens fiber cells of transgenic mice. Dev Neurosci. 2004; 26(5-6):435-45.
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Myc requires distinct E2F activities to induce S phase and apoptosis. Mol Cell. 2001 Jul; 8(1):105-13.