"Multigene Family" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A set of genes descended by duplication and variation from some ancestral gene. Such genes may be clustered together on the same chromosome or dispersed on different chromosomes. Examples of multigene families include those that encode the hemoglobins, immunoglobulins, histocompatibility antigens, actins, tubulins, keratins, collagens, heat shock proteins, salivary glue proteins, chorion proteins, cuticle proteins, yolk proteins, and phaseolins, as well as histones, ribosomal RNA, and transfer RNA genes. The latter three are examples of reiterated genes, where hundreds of identical genes are present in a tandem array. (King & Stanfield, A Dictionary of Genetics, 4th ed)
| Descriptor ID |
D005810
|
| MeSH Number(s) |
G05.360.340.024.340.645
|
| Concept/Terms |
Multigene Family- Multigene Family
- Families, Multigene
- Family, Multigene
- Multigene Families
Gene Clusters- Gene Clusters
- Cluster, Gene
- Clusters, Gene
- Gene Cluster
|
Below are MeSH descriptors whose meaning is more general than "Multigene Family".
Below are MeSH descriptors whose meaning is more specific than "Multigene Family".
This graph shows the total number of publications written about "Multigene Family" by people in this website by year, and whether "Multigene Family" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 2 | 2 |
| 1995 | 0 | 1 | 1 |
| 1996 | 0 | 1 | 1 |
| 1997 | 2 | 0 | 2 |
| 1998 | 0 | 1 | 1 |
| 1999 | 1 | 3 | 4 |
| 2000 | 4 | 1 | 5 |
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 6 | 6 |
| 2004 | 1 | 5 | 6 |
| 2006 | 0 | 2 | 2 |
| 2007 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 1 | 2 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 2 | 3 |
| 2012 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 1 | 2 |
| 2017 | 2 | 1 | 3 |
| 2018 | 0 | 2 | 2 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Multigene Family" by people in Profiles.
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Refactoring and Heterologous Expression of Class III Lanthipeptide Biosynthetic Gene Clusters Lead to the Discovery of N,N-Dimethylated Lantibiotics from Firmicutes. ACS Chem Biol. 2023 Mar 17; 18(3):508-517.
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Inhibition of Orai Channel Function Regulates Mas-Related G Protein-Coupled Receptor-Mediated Responses in Mast Cells. Front Immunol. 2021; 12:803335.
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Grincamycins P-T: Rearranged Angucyclines from the Marine Sediment-Derived Streptomyces sp. CNZ-748 Inhibit Cell Lines of the Rare Cancer Pseudomyxoma Peritonei. J Nat Prod. 2021 05 28; 84(5):1638-1648.
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PALMER: improving pathway annotation based on the biomedical literature mining with a constrained latent block model. BMC Bioinformatics. 2020 Oct 02; 21(1):432.
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The broken cycle: E2F dysfunction in?cancer. Nat Rev Cancer. 2019 06; 19(6):326-338.
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Arsenic Induces Members of the mmu-miR-466-669 Cluster Which Reduces NeuroD1 Expression. Toxicol Sci. 2018 03 01; 162(1):64-78.
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Characterization and Evidence of the miR-888 Cluster as a Novel Cancer Network in Prostate. Mol Cancer Res. 2018 04; 16(4):669-681.
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Direct inhibition of RAS: Quest for the Holy Grail? Semin Cancer Biol. 2019 02; 54:138-148.
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Correlated Mutation in the Evolution of Catalysis in Uracil DNA Glycosylase Superfamily. Sci Rep. 2017 04 11; 7:45978.
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Cloning, expression, purification and biophysical analysis of two putative halogenases from the glycopeptide A47,934 gene cluster of Streptomyces toyocaensis. Protein Expr Purif. 2017 04; 132:9-18.