"Base Pair Mismatch" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The presence of an uncomplimentary base in double-stranded DNA caused by spontaneous deamination of cytosine or adenine, mismatching during homologous recombination, or errors in DNA replication. Multiple, sequential base pair mismatches lead to formation of heteroduplex DNA; (NUCLEIC ACID HETERODUPLEXES).
| Descriptor ID |
D020137
|
| MeSH Number(s) |
G05.365.590.060
|
| Concept/Terms |
Base Pair Mismatch- Base Pair Mismatch
- Mismatch, Base Pair
- Base Pair Mismatches
- Mismatches, Base Pair
|
Below are MeSH descriptors whose meaning is more general than "Base Pair Mismatch".
Below are MeSH descriptors whose meaning is more specific than "Base Pair Mismatch".
This graph shows the total number of publications written about "Base Pair Mismatch" by people in this website by year, and whether "Base Pair Mismatch" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 1 | 2 |
| 2003 | 2 | 1 | 3 |
| 2004 | 0 | 1 | 1 |
| 2005 | 1 | 1 | 2 |
| 2006 | 1 | 1 | 2 |
| 2010 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Base Pair Mismatch" by people in Profiles.
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A structural determinant in the uracil DNA glycosylase superfamily for the removal of uracil from adenine/uracil base pairs. Nucleic Acids Res. 2015 Jan; 43(2):1081-9.
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Identification of Escherichia coli mismatch-specific uracil DNA glycosylase as a robust xanthine DNA glycosylase. J Biol Chem. 2010 Dec 31; 285(53):41483-90.
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The DNA N-glycosylase MED1 exhibits preference for halogenated pyrimidines and is involved in the cytotoxicity of 5-iododeoxyuridine. Cancer Res. 2006 Aug 01; 66(15):7686-93.
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Expression of DNA mismatch repair gene MSH2 in cytological material from lung cancer patients. Diagn Cytopathol. 2006 Jul; 34(7):463-6.
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Lower cancer incidence in Amsterdam-I criteria families without mismatch repair deficiency: familial colorectal cancer type X. JAMA. 2005 Apr 27; 293(16):1979-85.
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Conversion analysis for mutation detection in MLH1 and MSH2 in patients with colorectal cancer. JAMA. 2005 Feb 16; 293(7):799-809.
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Effects of deletion and site-directed mutations on ligation steps of NAD+-dependent DNA ligase: a biochemical analysis of BRCA1 C-terminal domain. Biochemistry. 2004 Oct 05; 43(39):12648-59.
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The adaptive imbalance in base excision-repair enzymes generates microsatellite instability in chronic inflammation. J Clin Invest. 2003 Dec; 112(12):1887-94.
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In vitro and in vivo modulations of benzo[c]phenanthrene-DNA adducts by DNA mismatch repair system. Nucleic Acids Res. 2003 Nov 15; 31(22):6428-34.
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Alterations in PMS2, MSH2 and MLH1 expression in human prostate cancer. Int J Oncol. 2003 May; 22(5):1033-43.