"Receptor, IGF Type 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A receptor that is specific for IGF-II and mannose-6-phosphate. The receptor is a 250-kDa single chain polypeptide which is unrelated in structure to the type 1 IGF receptor (RECEPTOR, IGF TYPE 1) and does not have a tyrosine kinase domain.
| Descriptor ID |
D017527
|
| MeSH Number(s) |
D12.776.543.750.750.400.780.410
|
| Concept/Terms |
Receptor, IGF Type 2- Receptor, IGF Type 2
- IGF-2 Receptor
- IGF 2 Receptor
- Receptor, IGF-2
- IGF-II Receptor
- IGF II Receptor
- Insulin-Like-Growth-Factor II Receptor
- Insulin Like Growth Factor II Receptor
- Receptor, Insulin-Like-Growth-Factor II
- Mannose-6-Phosphate Receptor
- Mannose 6 Phosphate Receptor
- Receptor, Insulin-Like Growth Factor II
- Receptor, Insulin Like Growth Factor II
- Receptor, Insulin-Like Growth Factor Type 2
- Receptor, Insulin Like Growth Factor Type 2
- Receptor, Mannose-6-Phosphate
- Receptor, Mannose 6 Phosphate
- Receptors, IGF-2
- IGF-2 Receptors
- Receptors, IGF 2
- Receptors, Insulin-Like Growth Factor II
- Receptors, Insulin Like Growth Factor II
- IGF Type 2 Receptor
- Receptor, IGF-II
- Receptor, IGF II
|
Below are MeSH descriptors whose meaning is more general than "Receptor, IGF Type 2".
Below are MeSH descriptors whose meaning is more specific than "Receptor, IGF Type 2".
This graph shows the total number of publications written about "Receptor, IGF Type 2" by people in this website by year, and whether "Receptor, IGF Type 2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2011 | 0 | 2 | 2 |
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Below are the most recent publications written about "Receptor, IGF Type 2" by people in Profiles.
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Phospholipase C and protein kinase C-? 2 mediate insulin-like growth factor II-dependent sphingosine kinase 1 activation. Mol Endocrinol. 2011 Dec; 25(12):2144-56.
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IGF signaling directs ventricular cardiomyocyte proliferation during embryonic heart development. Development. 2011 May; 138(9):1795-805.
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Insulin-like growth factor-2/mannose-6 phosphate receptors. Vitam Horm. 2009; 80:667-97.
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The insulin-like growth factor type 1 and insulin-like growth factor type 2/mannose-6-phosphate receptors independently regulate ERK1/2 activity in HEK293 cells. J Biol Chem. 2007 Sep 07; 282(36):26150-7.
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Inhibition of growth and reduction in tumorigenicity of UCI-107 ovarian cancer by antagonists of growth hormone-releasing hormone and vasoactive intestinal peptide. J Cancer Res Clin Oncol. 2001 Nov; 127(11):645-52.
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Inhibition of insulin like growth factor II autocrine growth of Wilms' tumor by suramin in vitro and in vivo. Cancer Lett. 1996 May 15; 103(1):49-56.
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Expression of insulin-like growth factor-II (IGF-II) and IGF-II/mannose-6-phosphate receptor in the rat hippocampus: an in situ hybridization and immunocytochemical study. Endocrinology. 1992 Oct; 131(4):1636-42.
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Five related Lebanese individuals with high plasma lysosomal hydrolases: a new defect in mannose-6-phosphate receptor recognition? Am J Hum Genet. 1984 Sep; 36(5):1001-14.