"Cytosine Deaminase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme which catalyzes the deamination of CYTOSINE resulting in the formation of URACIL. It can also act on 5-methylcytosine to form THYMIDINE.
| Descriptor ID |
D043525
|
| MeSH Number(s) |
D08.811.277.151.486.625
|
| Concept/Terms |
Cytosine Deaminase- Cytosine Deaminase
- Deaminase, Cytosine
- Cytosine Aminohydrolase
- Aminohydrolase, Cytosine
|
Below are MeSH descriptors whose meaning is more general than "Cytosine Deaminase".
Below are MeSH descriptors whose meaning is more specific than "Cytosine Deaminase".
This graph shows the total number of publications written about "Cytosine Deaminase" by people in this website by year, and whether "Cytosine Deaminase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cytosine Deaminase" by people in Profiles.
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Effect of Vocimagene Amiretrorepvec in Combination With Flucytosine vs Standard of Care on Survival Following Tumor Resection in Patients With Recurrent High-Grade Glioma: A Randomized Clinical Trial. JAMA Oncol. 2020 12 01; 6(12):1939-1946.
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Fab-based inhibitors reveal ubiquitin independent functions for HIV Vif neutralization of APOBEC3 restriction factors. PLoS Pathog. 2018 01; 14(1):e1006830.
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CBF? and HIV Infection. Adv Exp Med Biol. 2017; 962:415-431.
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Lineage-Specific Viral Hijacking of Non-canonical E3?Ubiquitin Ligase Cofactors in the Evolution of Vif Anti-APOBEC3 Activity. Cell Rep. 2015 May 26; 11(8):1236-50.
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CBF? stabilizes HIV Vif to counteract APOBEC3 at the expense of RUNX1 target gene expression. Mol Cell. 2013 Feb 21; 49(4):632-44.
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The present and future for gene and viral therapy of directly accessible prostate and squamous cell cancers of the head and neck. Future Oncol. 2005 Feb; 1(1):115-23.
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Cytotoxic T lymphocyte responses to proteins encoded by heterologous transgenes transferred in vivo by adenoviral vectors. Hum Gene Ther. 1997 Jul 01; 8(10):1207-17.