"Leukotriene B4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The major metabolite in neutrophil polymorphonuclear leukocytes. It stimulates polymorphonuclear cell function (degranulation, formation of oxygen-centered free radicals, arachidonic acid release, and metabolism). (From Dictionary of Prostaglandins and Related Compounds, 1990)
| Descriptor ID |
D007975
|
| MeSH Number(s) |
D10.251.355.255.100.450.411 D10.251.355.310.166.887.411 D23.469.050.175.450.415
|
| Concept/Terms |
Leukotriene B4- Leukotriene B4
- Leukotriene B-4
- B-4, Leukotriene
- Leukotriene B 4
- LTB4
|
Below are MeSH descriptors whose meaning is more general than "Leukotriene B4".
Below are MeSH descriptors whose meaning is more specific than "Leukotriene B4".
This graph shows the total number of publications written about "Leukotriene B4" by people in this website by year, and whether "Leukotriene B4" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Leukotriene B4" by people in Profiles.
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Oral administration of cytosolic PLA2 inhibitor arachidonyl trifluoromethyl ketone ameliorates cauda equina compression injury in rats. J Neuroinflammation. 2015 May 15; 12:94.
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Leukotriene B4 enhances innate immune defense against the puerperal sepsis agent Streptococcus pyogenes. J Immunol. 2013 Feb 15; 190(4):1614-22.
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Macrophage-produced IL-12p70 mediates hemorrhage-induced damage in a complement-dependent manner. Shock. 2011 Feb; 35(2):134-40.
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Blockade of alpha 5 beta 1 integrins reverses the inhibitory effect of tenascin on chemotaxis of human monocytes and polymorphonuclear leukocytes through three-dimensional gels of extracellular matrix proteins. J Immunol. 2001 Jun 15; 166(12):7534-42.
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Differential regulation of beta1 integrins by chemoattractants regulates neutrophil migration through fibrin. J Cell Biol. 1999 Mar 08; 144(5):1047-56.
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Leukotriene B4 release and polymorphonuclear cell infiltration in spinal cord injury. J Neurochem. 1990 Sep; 55(3):907-12.
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Essential fatty acid-deficient rats are resistant to oleic acid-induced pulmonary injury. J Appl Physiol (1985). 1989 Aug; 67(2):811-6.
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Oleic acid-induced pulmonary injury in rats: potential role of sulfidopeptide leukotrienes. Circ Shock. 1988 Sep; 26(1):59-70.
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Activation of the lipoxygenase pathway in the methionine enkephalin induced respiratory burst in human polymorphonuclear leukocytes. Life Sci. 1988; 42(22):2299-306.
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[The role of thromboxane A2, prostaglandin I2 and leukotrienes in cerebral ischemia]. Changgeng Yi Xue Za Zhi. 1986 Jun 20; 9(2):139-45.