"alpha-Crystallin B Chain" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the alpha crystallin subunits. In addition to being expressed in the lens (LENS, CRYSTALLINE), alpha-crystallin B chain has been found in a variety of tissues such as HEART; BRAIN; MUSCLE; and KIDNEY. Accumulation of the protein in the brain is associated with NEURODEGENERATIVE DISEASES such as CREUTZFELDT-JAKOB SYNDROME and ALEXANDER DISEASE.
Descriptor ID |
D038203
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MeSH Number(s) |
D12.776.306.366.100.300 D12.776.580.157.300
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Concept/Terms |
alpha-Crystallin B Chain- alpha-Crystallin B Chain
- B Chain, alpha-Crystallin
- alpha Crystallin B Chain
- Rosenthal Fiber Component
- alpha-Crystallin, B Subunit
- B Subunit alpha-Crystallin
- alpha Crystallin, B Subunit
- alpha B-Crystallin
- alpha B Crystallin
- Crystallins, alpha B Chain
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Below are MeSH descriptors whose meaning is more general than "alpha-Crystallin B Chain".
Below are MeSH descriptors whose meaning is more specific than "alpha-Crystallin B Chain".
This graph shows the total number of publications written about "alpha-Crystallin B Chain" by people in this website by year, and whether "alpha-Crystallin B Chain" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "alpha-Crystallin B Chain" by people in Profiles.
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TFEB activation protects against cardiac proteotoxicity via increasing autophagic flux. J Mol Cell Cardiol. 2017 12; 113:51-62.
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Lysine 269 is essential for cyclin D1 ubiquitylation by the SCF(Fbx4/alphaB-crystallin) ligase and subsequent proteasome-dependent degradation. Oncogene. 2009 Dec 10; 28(49):4317-25.
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SCF(Fbx4/alphaB-crystallin) E3 ligase: when one is not enough. Cell Cycle. 2008 Oct; 7(19):2983-6.
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Phosphorylation-dependent ubiquitination of cyclin D1 by the SCF(FBX4-alphaB crystallin) complex. Mol Cell. 2006 Nov 03; 24(3):355-66.