"Sirtuin 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A sirtuin family member found primarily in the CELL NUCLEUS. It is an NAD-dependent deacetylase with specificity towards HISTONES and a variety of proteins involved in gene regulation.
| Descriptor ID |
D056564
|
| MeSH Number(s) |
D08.811.277.087.520.200.650.100 D12.776.476.900.100
|
| Concept/Terms |
Sirtuin 1- Sirtuin 1
- Silent Mating Type Information Regulation 2 Homolog 1
|
Below are MeSH descriptors whose meaning is more general than "Sirtuin 1".
Below are MeSH descriptors whose meaning is more specific than "Sirtuin 1".
This graph shows the total number of publications written about "Sirtuin 1" by people in this website by year, and whether "Sirtuin 1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2009 | 1 | 1 | 2 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 1 | 2 |
| 2013 | 2 | 1 | 3 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2017 | 1 | 1 | 2 |
| 2018 | 2 | 1 | 3 |
| 2019 | 2 | 1 | 3 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Sirtuin 1" by people in Profiles.
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The Role of Epigenetic Regulator SIRT1 in Balancing the Homeostasis and Preventing the Formation of Specific "Soil" of Metabolic Disorders and Related Cancers. Front Biosci (Landmark Ed). 2022 08 31; 27(9):253.
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The effect of daily intake of vitamin D-fortified yogurt drink, with and without added calcium, on serum adiponectin and sirtuins 1 and 6 in adult subjects with type 2 diabetes. Nutr Diabetes. 2021 07 30; 11(1):26.
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CD38: Modulating Histone Methyltransferase EZH2 Activity in SLE. Trends Immunol. 2020 03; 41(3):187-189.
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Alpha-calcitonin gene-related peptide prevents pressure-overload induced heart failure: role of apoptosis and oxidative stress. Physiol Rep. 2019 11; 7(21):e14269.
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CD38-NAD+-Sirt1 axis in T cell immunotherapy. Aging (Albany NY). 2019 10 23; 11(20):8743-8744.
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Nicotinamide N-methyltransferase enhances chemoresistance in breast cancer through SIRT1 protein stabilization. Breast Cancer Res. 2019 05 17; 21(1):64.
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Targeting Sirt-1 controls GVHD by inhibiting T-cell allo-response and promoting Treg stability in mice. Blood. 2019 01 17; 133(3):266-279.
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The Effect of Diet on Improved Endurance in Male C57BL/6 Mice. Nutrients. 2018 Aug 16; 10(8).
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Kallistatin attenuates endothelial senescence by modulating Let-7g-mediated miR-34a-SIRT1-eNOS pathway. J Cell Mol Med. 2018 09; 22(9):4387-4398.
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CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response. Cell Metab. 2018 01 09; 27(1):85-100.e8.