"Formyltetrahydrofolates" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Tetrahydrofolates which are substituted by a formyl group at either the nitrogen atom in the 5 position or the nitrogen atom in the 10 position. N(5)-Formyltetrahydrofolate is leukovorin (citrovorum factor) while N(10)-formyltetrahydrofolate is an active coenzyme which functions as a carrier of the formyl group in a number of enzymatic reactions.
| Descriptor ID |
D005575
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| MeSH Number(s) |
D03.633.100.733.631.400.800.350 D08.211.840.300
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Formyltetrahydrofolates".
Below are MeSH descriptors whose meaning is more specific than "Formyltetrahydrofolates".
This graph shows the total number of publications written about "Formyltetrahydrofolates" by people in this website by year, and whether "Formyltetrahydrofolates" was a major or minor topic of these publications.
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Below are the most recent publications written about "Formyltetrahydrofolates" by people in Profiles.
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Inhibition of mammalian thymidylate synthase by 10-formyltetrahydropteroylpolyglutamate. Arch Biochem Biophys. 1991 Jan; 284(1):219-22.
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A radioenzymatic method for the determination of tissue 10-formyltetrahydrofolate. J Biochem Biophys Methods. 1986 Jun; 12(5-6):311-7.