SKP Cullin F-Box Protein Ligases
"SKP Cullin F-Box Protein Ligases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subset of ubiquitin protein ligases that are formed by the association of a SKP DOMAIN PROTEIN, a CULLIN DOMAIN PROTEIN and a F-BOX DOMAIN PROTEIN.
| Descriptor ID |
D044843
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| MeSH Number(s) |
D08.811.464.938.750.750
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| Concept/Terms |
SKP1-Cullin Ubiquitin Ligases- SKP1-Cullin Ubiquitin Ligases
- Ligases, SKP1-Cullin Ubiquitin
- SKP1 Cullin Ubiquitin Ligases
- Ubiquitin Ligases, SKP1-Cullin
- Skp1-Cullin-1-F-box Ubiquitin Ligase
- Ligase, Skp1-Cullin-1-F-box Ubiquitin
- Skp1 Cullin 1 F box Ubiquitin Ligase
- Ubiquitin Ligase, Skp1-Cullin-1-F-box
- Skp1-Cullin-F-Box Proteins
- Skp1 Cullin F Box Proteins
|
Below are MeSH descriptors whose meaning is more general than "SKP Cullin F-Box Protein Ligases".
Below are MeSH descriptors whose meaning is more specific than "SKP Cullin F-Box Protein Ligases".
This graph shows the total number of publications written about "SKP Cullin F-Box Protein Ligases" by people in this website by year, and whether "SKP Cullin F-Box Protein Ligases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2015 | 0 | 2 | 2 |
| 2019 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "SKP Cullin F-Box Protein Ligases" by people in Profiles.
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A SARS-CoV-2 protein interaction map reveals targets for drug repurposing. Nature. 2020 07; 583(7816):459-468.
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Cyclin F Controls Cell-Cycle Transcriptional Outputs by Directing the Degradation of the Three Activator E2Fs. Mol Cell. 2019 06 20; 74(6):1264-1277.e7.
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Preclinical Investigation of the Novel Histone Deacetylase Inhibitor AR-42 in the Treatment of Cancer-Induced Cachexia. J Natl Cancer Inst. 2015 Dec; 107(12):djv274.
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Akt-mediated phosphorylation of XLF impairs non-homologous end-joining DNA repair. Mol Cell. 2015 Feb 19; 57(4):648-661.
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SCFs in the new millennium. Oncogene. 2014 Apr 17; 33(16):2011-8.
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The Fbx4 tumor suppressor regulates cyclin D1 accumulation and prevents neoplastic transformation. Mol Cell Biol. 2011 Nov; 31(22):4513-23.
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Mitochondria-targeted antioxidants protect against mechanical ventilation-induced diaphragm weakness. Crit Care Med. 2011 Jul; 39(7):1749-59.
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Phosphorylation-dependent regulation of SCF(Fbx4) dimerization and activity involves a novel component, 14-3-3?. Oncogene. 2011 Apr 28; 30(17):1995-2002.
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Structural basis of selective ubiquitination of TRF1 by SCFFbx4. Dev Cell. 2010 Feb 16; 18(2):214-25.
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Lysine 269 is essential for cyclin D1 ubiquitylation by the SCF(Fbx4/alphaB-crystallin) ligase and subsequent proteasome-dependent degradation. Oncogene. 2009 Dec 10; 28(49):4317-25.