Inhibitor of Apoptosis Proteins
"Inhibitor of Apoptosis Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A conserved class of proteins that control APOPTOSIS in both VERTEBRATES and INVERTEBRATES. IAP proteins interact with and inhibit CASPASES, and they function as ANTI-APOPTOTIC PROTEINS. The protein class is defined by an approximately 80-amino acid motif called the baculoviral inhibitor of apoptosis repeat; some members have ubiquitin-protein ligase activity.
| Descriptor ID |
D051034
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| MeSH Number(s) |
D08.811.464.938.750.210 D12.644.360.075.437 D12.776.476.075.437
|
| Concept/Terms |
Inhibitor of Apoptosis Proteins- Inhibitor of Apoptosis Proteins
- Apoptosis Proteins Inhibitor
- Inhibitor-Of-Apoptosis Protein
- Inhibitor Of Apoptosis Protein
- Baculoviral Inhibitor Of Apoptosis Repeat Proteins
- IAP Repeat Containing Proteins
- IAP Protein (Apoptosis)
Baculoviral IAP Repeat-Containing 2 Protein- Baculoviral IAP Repeat-Containing 2 Protein
- Baculoviral IAP Repeat Containing 2 Protein
- Cellular Inhibitor of Apoptosis 1 Protein
- IAP2 Protein
- c-IAP1 Protein
- cIAP1 Protein
- Inhibitor of Apoptosis 2 Protein
- BIRC2 Protein
- Baculoviral IAP Repeat Containing Protein 2
|
Below are MeSH descriptors whose meaning is more general than "Inhibitor of Apoptosis Proteins".
Below are MeSH descriptors whose meaning is more specific than "Inhibitor of Apoptosis Proteins".
This graph shows the total number of publications written about "Inhibitor of Apoptosis Proteins" by people in this website by year, and whether "Inhibitor of Apoptosis Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 2 | 2 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 3 | 4 |
| 2008 | 0 | 2 | 2 |
| 2009 | 0 | 3 | 3 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 3 | 3 |
| 2012 | 2 | 0 | 2 |
| 2013 | 0 | 2 | 2 |
| 2014 | 1 | 1 | 2 |
| 2015 | 0 | 1 | 1 |
| 2016 | 2 | 0 | 2 |
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Below are the most recent publications written about "Inhibitor of Apoptosis Proteins" by people in Profiles.
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miR-30e Blocks Autophagy and Acts Synergistically with Proanthocyanidin for Inhibition of AVEN and BIRC6 to Increase Apoptosis in Glioblastoma Stem Cells and Glioblastoma SNB19 Cells. PLoS One. 2016; 11(7):e0158537.
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Sequestering survivin to functionalized nanoparticles: a strategy to enhance apoptosis in cancer cells. Biomater Sci. 2016 Apr; 4(4):614-26.
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Paclitaxel tumor priming promotes delivery and transfection of intravenous lipid-siRNA in pancreatic tumors. J Control Release. 2015 Oct 28; 216:103-10.
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Tumor priming enhances siRNA delivery and transfection in intraperitoneal tumors. J Control Release. 2014 Mar 28; 178:79-85.
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Ceramide targets xIAP and cIAP1 to sensitize metastatic colon and breast cancer cells to apoptosis induction to suppress tumor progression. BMC Cancer. 2014 Jan 15; 14:24.
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Molecular chaperone gp96 is a novel therapeutic target of multiple myeloma. Clin Cancer Res. 2013 Nov 15; 19(22):6242-51.
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Reining in nuclear factor-kappaB in skeletal muscle disorders. Curr Opin Clin Nutr Metab Care. 2013 May; 16(3):251-7.
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Plasma-derived exosomal survivin, a plausible biomarker for early detection of prostate cancer. PLoS One. 2012; 7(10):e46737.
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Survivin knockdown increased anti-cancer effects of (-)-epigallocatechin-3-gallate in human malignant neuroblastoma SK-N-BE2 and SH-SY5Y cells. Exp Cell Res. 2012 Aug 01; 318(13):1597-610.
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Overcoming hypoxia-induced apoptotic resistance through combinatorial inhibition of GSK-3? and CDK1. Cancer Res. 2011 Aug 01; 71(15):5265-75.