Proto-Oncogene Proteins pp60(c-src)
"Proto-Oncogene Proteins pp60(c-src)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Membrane-associated tyrosine-specific kinases encoded by the c-src genes. They have an important role in cellular growth control. Truncation of carboxy-terminal residues in pp60(c-src) leads to PP60(V-SRC) which has the ability to transform cells. This kinase pp60 c-src should not be confused with csk, also known as c-src kinase.
| Descriptor ID |
D016392
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| MeSH Number(s) |
D08.811.913.696.620.682.725.800.630 D12.776.624.664.700.202
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| Concept/Terms |
Proto-Oncogene Proteins pp60(c-src)- Proto-Oncogene Proteins pp60(c-src)
- Phosphoprotein pp60(c-src)
- pp60 c-src
- c-src, pp60
- pp60 c src
- pp60(c-src)
- Proto-Oncogene Protein src
- Protein src, Proto-Oncogene
- Proto Oncogene Protein src
- src Proto-Oncogene Product
- Proto-Oncogene Product, src
- src Proto Oncogene Product
- src Proto-Oncogene Protein pp60
- src Proto Oncogene Protein pp60
- c-src Protein pp60
- Protein pp60, c-src
- c src Protein pp60
- pp60, c-src Protein
- Proto-Oncogene Protein pp60(c-src)
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Below are MeSH descriptors whose meaning is more general than "Proto-Oncogene Proteins pp60(c-src)".
Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogene Proteins pp60(c-src)".
This graph shows the total number of publications written about "Proto-Oncogene Proteins pp60(c-src)" by people in this website by year, and whether "Proto-Oncogene Proteins pp60(c-src)" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 2 | 0 | 2 |
| 1999 | 1 | 0 | 1 |
| 2000 | 1 | 1 | 2 |
| 2005 | 0 | 1 | 1 |
| 2008 | 2 | 0 | 2 |
| 2009 | 1 | 1 | 2 |
| 2014 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Proto-Oncogene Proteins pp60(c-src)" by people in Profiles.
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Blocking Myristoylation of Src Inhibits Its Kinase Activity and Suppresses Prostate Cancer Progression. Cancer Res. 2017 12 15; 77(24):6950-6962.
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Endothelial nitric-oxide synthase (eNOS) is activated through G-protein-coupled receptor kinase-interacting protein 1 (GIT1) tyrosine phosphorylation and Src protein. J Biol Chem. 2014 Jun 27; 289(26):18163-74.
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A novel signaling pathway of tissue kallikrein in promoting keratinocyte migration: activation of proteinase-activated receptor 1 and epidermal growth factor receptor. Exp Cell Res. 2010 Feb 01; 316(3):376-89.
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Activation of Src by protein tyrosine phosphatase 1B Is required for ErbB2 transformation of human breast epithelial cells. Cancer Res. 2009 Jun 01; 69(11):4582-8.
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Histidine triad nucleotide-binding protein 1 up-regulates cellular levels of p27KIP1 by targeting ScfSKP2 ubiquitin ligase and Src. J Biol Chem. 2009 Feb 20; 284(8):5265-76.
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Met and c-Src cooperate to compensate for loss of epidermal growth factor receptor kinase activity in breast cancer cells. Cancer Res. 2008 May 01; 68(9):3314-22.
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Prevention of noise-induced hearing loss with Src-PTK inhibitors. Hear Res. 2005 Oct; 208(1-2):14-25.
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Direct binding of activated c-Src to the beta 3-adrenergic receptor is required for MAP kinase activation. J Biol Chem. 2000 Dec 08; 275(49):38131-4.
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Integrin activation and focal complex formation in cardiac hypertrophy. J Biol Chem. 2000 Nov 10; 275(45):35624-30.
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Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes. Science. 1999 Jan 29; 283(5402):655-61.