"src-Family Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A PROTEIN-TYROSINE KINASE family that was originally identified by homology to the Rous sarcoma virus ONCOGENE PROTEIN PP60(V-SRC). They interact with a variety of cell-surface receptors and participate in intracellular signal transduction pathways. Oncogenic forms of src-family kinases can occur through altered regulation or expression of the endogenous protein and by virally encoded src (v-src) genes.
| Descriptor ID |
D019061
|
| MeSH Number(s) |
D08.811.913.696.620.682.725.800
|
| Concept/Terms |
src-Family Kinases- src-Family Kinases
- src Family Kinases
- src-Family Tyrosine Kinases
- Tyrosine Kinases, src-Family
- src Family Tyrosine Kinases
- src Tyrosine Kinases
- Kinases, src Tyrosine
- Tyrosine Kinases, src
- Protein-Tyrosine Kinases, src
- Kinases, src Protein-Tyrosine
- src Protein-Tyrosine Kinases
- src Kinases
- Kinases, src
|
Below are MeSH descriptors whose meaning is more general than "src-Family Kinases".
Below are MeSH descriptors whose meaning is more specific than "src-Family Kinases".
This graph shows the total number of publications written about "src-Family Kinases" by people in this website by year, and whether "src-Family Kinases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 2 | 2 |
| 1997 | 1 | 1 | 2 |
| 1999 | 0 | 5 | 5 |
| 2000 | 0 | 2 | 2 |
| 2001 | 1 | 0 | 1 |
| 2002 | 2 | 4 | 6 |
| 2003 | 3 | 2 | 5 |
| 2004 | 2 | 2 | 4 |
| 2005 | 3 | 1 | 4 |
| 2006 | 2 | 3 | 5 |
| 2007 | 1 | 1 | 2 |
| 2008 | 1 | 3 | 4 |
| 2009 | 2 | 0 | 2 |
| 2010 | 1 | 1 | 2 |
| 2011 | 1 | 2 | 3 |
| 2012 | 1 | 1 | 2 |
| 2013 | 2 | 1 | 3 |
| 2014 | 4 | 1 | 5 |
| 2015 | 2 | 0 | 2 |
| 2016 | 1 | 1 | 2 |
| 2017 | 1 | 2 | 3 |
| 2018 | 1 | 0 | 1 |
| 2019 | 2 | 1 | 3 |
| 2021 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "src-Family Kinases" by people in Profiles.
-
Constitutively active Lyn kinase causes a cutaneous small vessel vasculitis and liver fibrosis syndrome. Nat Commun. 2023 Mar 17; 14(1):1502.
-
Sublethal doxorubicin promotes migration and invasion of breast cancer cells: role of Src Family non-receptor tyrosine kinases. Breast Cancer Res. 2021 07 27; 23(1):76.
-
Lyn regulates creatine uptake in an imatinib-resistant CML cell line. Biochim Biophys Acta Gen Subj. 2020 04; 1864(4):129507.
-
Dynamic anticipation by Cdk2/Cyclin A-bound p27 mediates signal integration in cell cycle regulation. Nat Commun. 2019 04 11; 10(1):1676.
-
Dietary palmitate cooperates with Src kinase to promote prostate tumor progression. Prostate. 2019 06; 79(8):896-908.
-
A Catalytically Disabled Double Mutant of Src Tyrosine Kinase Can Be Stabilized into an Active-Like Conformation. J Mol Biol. 2018 03 16; 430(6):881-889.
-
Role of Src Family Kinases in BDNF-Mediated Suppression of Cocaine-Seeking and Prevention of Cocaine-Induced ERK, GluN2A, and GluN2B Dephosphorylation in the Prelimbic Cortex. Neuropsychopharmacology. 2017 Sep; 42(10):1972-1980.
-
Bladder cancer cell growth and motility implicate cannabinoid 2 receptor-mediated modifications of sphingolipids metabolism. Sci Rep. 2017 02 13; 7:42157.
-
Reversal of maladaptive fibrosis and compromised ventricular function in the pressure overloaded heart by a caveolin-1 surrogate peptide. Lab Invest. 2017 04; 97(4):370-382.
-
The cystic fibrosis transmembrane conductance regulator controls biliary epithelial inflammation and permeability by regulating Src tyrosine kinase activity. Hepatology. 2016 12; 64(6):2118-2134.