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    • Minocycline up-regulates Bcl-2 and protects against cell death in mitochondria.
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Minocycline up-regulates Bcl-2 and protects against cell death in mitochondria.

Minocycline up-regulates Bcl-2 and protects against cell death in mitochondria. J Biol Chem. 2004 May 07; 279(19):19948-54.

View in: PubMed

subject areas
  • Animals
  • Anti-Bacterial Agents
  • Apoptosis
  • bcl-2 Homologous Antagonist-Killer Protein
  • bcl-2-Associated X Protein
  • Caspases
  • Cell Death
  • Cells, Cultured
  • Cisplatin
  • Cytosol
  • Dose-Response Relationship, Drug
  • Down-Regulation
  • Enzyme Activation
  • Epithelial Cells
  • Hypoxia
  • In Situ Nick-End Labeling
  • Ischemia
  • Kidney
  • Male
  • Membrane Proteins
  • Microscopy, Fluorescence
  • Minocycline
  • Mitochondria
  • Oligonucleotides, Antisense
  • Precipitin Tests
  • Proto-Oncogene Proteins
  • Proto-Oncogene Proteins c-bcl-2
  • Rats
  • Rats, Sprague-Dawley
  • Reverse Transcriptase Polymerase Chain Reaction
  • RNA, Messenger
  • Sodium Azide
  • Staurosporine
  • Subcellular Fractions
  • Time Factors
  • Up-Regulation

authors with profiles
  • William David Hill