"CDC2-CDC28 Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of cell cycle-dependent kinases that are related in structure to CDC28 PROTEIN KINASE; S CEREVISIAE; and the CDC2 PROTEIN KINASE found in mammalian species.
| Descriptor ID |
D042846
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.646.500.500 D12.644.360.250.067 D12.776.167.200.067 D12.776.476.250.067
|
| Concept/Terms |
CDC2-CDC28 Kinases- CDC2-CDC28 Kinases
- CDC2 CDC28 Kinases
- CDC2+-CDC28-related Protein Kinase
- CDC2+ CDC28 related Protein Kinase
|
Below are MeSH descriptors whose meaning is more general than "CDC2-CDC28 Kinases".
Below are MeSH descriptors whose meaning is more specific than "CDC2-CDC28 Kinases".
This graph shows the total number of publications written about "CDC2-CDC28 Kinases" by people in this website by year, and whether "CDC2-CDC28 Kinases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1995 | 2 | 0 | 2 |
| 1996 | 1 | 0 | 1 |
| 1997 | 3 | 0 | 3 |
| 1998 | 1 | 0 | 1 |
| 1999 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 1 | 2 | 3 |
| 2005 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "CDC2-CDC28 Kinases" by people in Profiles.
-
Strategies for the design of potent and selective kinase inhibitors. Curr Pharm Des. 2005; 11(14):1845-63.
-
Mapping the functional domains of the Golgi stacking factor GRASP65. J Biol Chem. 2005 Feb 11; 280(6):4921-8.
-
Cyclin-dependent kinase inhibition by the KLF6 tumor suppressor protein through interaction with cyclin D1. Cancer Res. 2004 Jun 01; 64(11):3885-91.
-
RANKL coordinates cell cycle withdrawal and differentiation in osteoclasts through the cyclin-dependent kinase inhibitors p27KIP1 and p21CIP1. J Bone Miner Res. 2004 Aug; 19(8):1339-48.
-
2-Anilino-4-(thiazol-5-yl)pyrimidine CDK inhibitors: synthesis, SAR analysis, X-ray crystallography, and biological activity. J Med Chem. 2004 Mar 25; 47(7):1662-75.
-
Insights into cyclin groove recognition: complex crystal structures and inhibitor design through ligand exchange. Structure. 2003 Dec; 11(12):1537-46.
-
Analysis of Cdc6 function in the assembly of mammalian prereplication complexes. Proc Natl Acad Sci U S A. 2002 Feb 05; 99(3):1347-52.
-
DNA damage invokes mismatch repair-dependent cyclin D1 attenuation and retinoblastoma signaling pathways to inhibit CDK2. J Biol Chem. 2002 Mar 08; 277(10):8372-81.
-
Collaborative role of E2F transcriptional activity and G1 cyclindependent kinase activity in the induction of S phase. Proc Natl Acad Sci U S A. 1999 Jun 08; 96(12):6626-31.
-
E2F3 activity is regulated during the cell cycle and is required for the induction of S phase. Genes Dev. 1998 Jul 15; 12(14):2120-30.