Ornithine Decarboxylase Inhibitors
"Ornithine Decarboxylase Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Substances and drugs that inhibit or block the activity of ORNITHINE DECARBOXYLASE.
| Descriptor ID |
D065108
|
| MeSH Number(s) |
D27.505.519.389.705
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Ornithine Decarboxylase Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "Ornithine Decarboxylase Inhibitors".
This graph shows the total number of publications written about "Ornithine Decarboxylase Inhibitors" by people in this website by year, and whether "Ornithine Decarboxylase Inhibitors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1997 | 2 | 0 | 2 |
| 2001 | 0 | 1 | 1 |
| 2013 | 0 | 2 | 2 |
| 2015 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ornithine Decarboxylase Inhibitors" by people in Profiles.
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Matheson E, Bain J. Hirsutism in Women. Am Fam Physician. 2019 08 01; 100(3):168-175.
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Saulnier Sholler GL, Gerner EW, Bergendahl G, MacArthur RB, VanderWerff A, Ashikaga T, Bond JP, Ferguson W, Roberts W, Wada RK, Eslin D, Kraveka JM, Kaplan J, Mitchell D, Parikh NS, Neville K, Sender L, Higgins T, Kawakita M, Hiramatsu K, Moriya SS, Bachmann AS. A Phase I Trial of DFMO Targeting Polyamine Addiction in Patients with Relapsed/Refractory Neuroblastoma. PLoS One. 2015; 10(5):e0127246.
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Hayes CS, DeFeo-Mattox K, Woster PM, Gilmour SK. Elevated ornithine decarboxylase activity promotes skin tumorigenesis by stimulating the recruitment of bulge stem cells but not via toxic polyamine catabolic metabolites. Amino Acids. 2014 Mar; 46(3):543-52.
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Nowotarski SL, Woster PM, Casero RA. Polyamines and cancer: implications for chemotherapy and chemoprevention. Expert Rev Mol Med. 2013 Feb 22; 15:e3.
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Kramer DL, Chang BD, Chen Y, Diegelman P, Alm K, Black AR, Roninson IB, Porter CW. Polyamine depletion in human melanoma cells leads to G1 arrest associated with induction of p21WAF1/CIP1/SDI1, changes in the expression of p21-regulated genes, and a senescence-like phenotype. Cancer Res. 2001 Nov 01; 61(21):7754-62.
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Lipke DW, Newman PS, Tofiq S, Guo H, Arcot SS, Aziz SM, Olson JW, Soltis EE. Multiple polyamine regulatory pathways control compensatory cardiovascular hypertrophy in coarctation hypertension. Clin Exp Hypertens. 1997 Apr; 19(3):269-95.
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Lipke DW, Newman PS, Tofiq S, Aziz SM, Soltis EE. Eflornithine alters changes in vascular responsiveness associated with coarctation hypertension. Clin Exp Hypertens. 1997 Apr; 19(3):297-312.
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Kindy MS, Hu Y, Dempsey RJ. Blockade of ornithine decarboxylase enzyme protects against ischemic brain damage. J Cereb Blood Flow Metab. 1994 Nov; 14(6):1040-5.