"THP-1 Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A human leukemia monocytic cell line derived from a patient with LEUKEMIA, MONOCYTIC, ACUTE. It is used as a model to study the function of MONOCYTES and MACROPHAGES, their signaling pathways, nutrient and drug transport.
| Descriptor ID |
D000074084
|
| MeSH Number(s) |
A11.251.210.190.815 A11.251.860.180.815
|
| Concept/Terms |
THP-1 Cells- THP-1 Cells
- Cell, THP-1
- Cells, THP-1
- THP 1 Cells
- THP-1 Cell
- THP-1 Cell Line
- Cell Line, THP-1
- Cell Lines, THP-1
- THP 1 Cell Line
- THP-1 Cell Lines
|
Below are MeSH descriptors whose meaning is more general than "THP-1 Cells".
Below are MeSH descriptors whose meaning is more specific than "THP-1 Cells".
This graph shows the total number of publications written about "THP-1 Cells" by people in this website by year, and whether "THP-1 Cells" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 0 | 1 | 1 |
| 2018 | 0 | 3 | 3 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "THP-1 Cells" by people in Profiles.
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Ceramide kinase regulates TNF-a-induced immune responses in human monocytic cells. Sci Rep. 2021 04 15; 11(1):8259.
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Cytotrophoblasts suppress macrophage-mediated inflammation through a contact-dependent mechanism. Am J Reprod Immunol. 2021 03; 85(3):e13352.
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Macrophage miR-34a Is a Key Regulator of Cholesterol Efflux and Atherosclerosis. Mol Ther. 2020 01 08; 28(1):202-216.
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Streptococcus agalactiae Induces Placental Macrophages To Release Extracellular Traps Loaded with Tissue Remodeling Enzymes via an Oxidative Burst-Dependent Mechanism. mBio. 2018 11 20; 9(6).
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SAMHD1 suppresses innate immune responses to viral infections and inflammatory stimuli by inhibiting the NF-?B and interferon pathways. Proc Natl Acad Sci U S A. 2018 04 17; 115(16):E3798-E3807.
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Withaferin A Associated Differential Regulation of Inflammatory Cytokines. Front Immunol. 2018; 9:195.
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Differing mechanisms of surviving phagosomal stress among group B Streptococcus strains of varying genotypes. Virulence. 2017 08 18; 8(6):924-937.