Transforming Growth Factor beta
"Transforming Growth Factor beta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A factor synthesized in a wide variety of tissues. It acts synergistically with TGF-alpha in inducing phenotypic transformation and can also act as a negative autocrine growth factor. TGF-beta has a potential role in embryonal development, cellular differentiation, hormone secretion, and immune function. TGF-beta is found mostly as homodimer forms of separate gene products TGF-beta1, TGF-beta2 or TGF-beta3. Heterodimers composed of TGF-beta1 and 2 (TGF-beta1.2) or of TGF-beta2 and 3 (TGF-beta2.3) have been isolated. The TGF-beta proteins are synthesized as precursor proteins.
| Descriptor ID |
D016212
|
| MeSH Number(s) |
D12.644.276.374.687 D12.644.276.954.775 D12.776.467.374.687 D12.776.467.942.775 D23.529.374.687 D23.529.942.775
|
| Concept/Terms |
Transforming Growth Factor beta- Transforming Growth Factor beta
- Milk Growth Factor
- Factor, Milk Growth
- Growth Factor, Milk
- TGF-beta
- TGFbeta
- Platelet Transforming Growth Factor
- Bone-Derived Transforming Growth Factor
- Bone Derived Transforming Growth Factor
|
Below are MeSH descriptors whose meaning is more general than "Transforming Growth Factor beta".
Below are MeSH descriptors whose meaning is more specific than "Transforming Growth Factor beta".
This graph shows the total number of publications written about "Transforming Growth Factor beta" by people in this website by year, and whether "Transforming Growth Factor beta" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 3 | 0 | 3 |
| 1995 | 2 | 2 | 4 |
| 1996 | 3 | 2 | 5 |
| 1997 | 5 | 0 | 5 |
| 1998 | 5 | 0 | 5 |
| 1999 | 6 | 3 | 9 |
| 2000 | 8 | 1 | 9 |
| 2001 | 5 | 1 | 6 |
| 2002 | 8 | 2 | 10 |
| 2003 | 8 | 7 | 15 |
| 2004 | 8 | 6 | 14 |
| 2005 | 5 | 8 | 13 |
| 2006 | 2 | 7 | 9 |
| 2007 | 3 | 7 | 10 |
| 2008 | 7 | 8 | 15 |
| 2009 | 7 | 2 | 9 |
| 2010 | 4 | 11 | 15 |
| 2011 | 6 | 7 | 13 |
| 2012 | 6 | 10 | 16 |
| 2013 | 3 | 3 | 6 |
| 2014 | 3 | 8 | 11 |
| 2015 | 4 | 3 | 7 |
| 2016 | 6 | 3 | 9 |
| 2017 | 3 | 0 | 3 |
| 2018 | 8 | 2 | 10 |
| 2019 | 4 | 3 | 7 |
| 2020 | 2 | 2 | 4 |
| 2021 | 2 | 5 | 7 |
| 2022 | 0 | 3 | 3 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Transforming Growth Factor beta" by people in Profiles.
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Reduced Cathepsin L expression and secretion into the extracellular milieu contribute to lung fibrosis in systemic sclerosis. Rheumatology (Oxford). 2023 03 01; 62(3):1306-1316.
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Characterization of focal adhesion proteins in rodent hepatic stellate cells. Histochem Cell Biol. 2022 Oct; 158(4):325-334.
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Safety, immunological effects and clinical response in a phase I trial of umbilical cord mesenchymal stromal cells in patients with treatment refractory SLE. Lupus Sci Med. 2022 07; 9(1).
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Pre-Clinical Autoimmunity in Lupus Relatives: Self-Reported Questionnaires and Immune Dysregulation Distinguish Relatives Who Develop Incomplete or Classified Lupus From Clinically Unaffected Relatives and Unaffected, Unrelated Individuals. Front Immunol. 2022; 13:866181.
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TGF?-induced expression of long noncoding lincRNA Platr18 controls breast cancer axonogenesis. Life Sci Alliance. 2022 02; 5(2).
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Elevated Fibronectin Levels in Profibrotic CD14+ Monocytes and CD14+ Macrophages in Systemic Sclerosis. Front Immunol. 2021; 12:642891.
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Targeting myosin 1c inhibits murine hepatic fibrogenesis. Am J Physiol Gastrointest Liver Physiol. 2021 06 01; 320(6):G1044-G1053.
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Elucidating the cellular mechanism for E2-induced dermal fibrosis. Arthritis Res Ther. 2021 02 27; 23(1):68.
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Protective role of kallistatin in renal fibrosis via modulation of Wnt/?-catenin signaling. Clin Sci (Lond). 2021 02 12; 135(3):429-446.
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Pathophysiology and Pathogenesis of Marfan Syndrome. Adv Exp Med Biol. 2021; 1348:185-206.