"Cyclin D1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Protein encoded by the bcl-1 gene which plays a critical role in regulating the cell cycle. Overexpression of cyclin D1 is the result of bcl-1 rearrangement, a t(11;14) translocation, and is implicated in various neoplasms.
| Descriptor ID |
D019938
|
| MeSH Number(s) |
D12.644.360.262.150.100 D12.776.167.218.150.100 D12.776.476.262.150.100 D12.776.624.664.700.100
|
| Concept/Terms |
Cyclin D1- Cyclin D1
- Proto-Oncogene Products bcl-1
- Proto Oncogene Products bcl 1
- Proto-Oncogene Protein bcl-1
- Proto Oncogene Protein bcl 1
- bcl-1, Proto-Oncogene Protein
- bcl-1 Proto-Oncogene Proteins
- Proto-Oncogene Proteins, bcl-1
- bcl 1 Proto Oncogene Proteins
- CCND1 Protein
- PRAD1 Protein
- bcl-1 Proto-Oncogene Products
- Proto-Oncogene Products, bcl-1
- bcl 1 Proto Oncogene Products
- bcl1 Proto-Oncogene Proteins
- Proto-Oncogene Proteins, bcl1
- bcl1 Proto Oncogene Proteins
- Proto-Oncogene Proteins c-bcl-1
- Proto Oncogene Proteins c bcl 1
- c-bcl-1, Proto-Oncogene Proteins
- c-bcl-1 Proteins
- c bcl 1 Proteins
|
Below are MeSH descriptors whose meaning is more general than "Cyclin D1".
Below are MeSH descriptors whose meaning is more specific than "Cyclin D1".
This graph shows the total number of publications written about "Cyclin D1" by people in this website by year, and whether "Cyclin D1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1999 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 1 | 1 | 2 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 3 | 3 |
| 2006 | 2 | 0 | 2 |
| 2007 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 1 | 2 |
| 2010 | 3 | 0 | 3 |
| 2012 | 0 | 3 | 3 |
| 2013 | 0 | 2 | 2 |
| 2015 | 0 | 2 | 2 |
| 2019 | 0 | 1 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cyclin D1" by people in Profiles.
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Non-phosphorylatable cyclin D1 mutant potentiates endometrial hyperplasia and drives carcinoma with Pten loss. Oncogene. 2022 04; 41(15):2187-2195.
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Targeting glutamine-addiction and overcoming CDK4/6 inhibitor resistance in human esophageal squamous cell carcinoma. Nat Commun. 2019 03 21; 10(1):1296.
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Interleukin-6 Prevents the Initiation but Enhances the Progression of Lung Cancer. Cancer Res. 2015 Aug 15; 75(16):3209-15.
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Consequence of the tumor-associated conversion to cyclin D1b. EMBO Mol Med. 2015 May; 7(5):628-47.
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PRMT5 is required for lymphomagenesis triggered by multiple oncogenic drivers. Cancer Discov. 2015 Mar; 5(3):288-303.
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FBXO4 loss facilitates carcinogen induced papilloma development in mice. Cancer Biol Ther. 2015; 16(5):750-5.
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Novel RNA chaperone domain of RNA-binding protein La is regulated by AKT phosphorylation. Nucleic Acids Res. 2015 Jan; 43(1):581-94.
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The FBXO4 tumor suppressor functions as a barrier to BRAFV600E-dependent metastatic melanoma. Mol Cell Biol. 2013 Nov; 33(22):4422-33.
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Kallistatin antagonizes Wnt/?-catenin signaling and cancer cell motility via binding to low-density lipoprotein receptor-related protein 6. Mol Cell Biochem. 2013 Jul; 379(1-2):295-301.
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ATM deficiency augments constitutively nuclear cyclin D1-driven genomic instability and lymphomagenesis. Oncogene. 2014 Jan 02; 33(1):129-33.