"Factor XI" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Stable blood coagulation factor involved in the intrinsic pathway. The activated form XIa activates factor IX to IXa. Deficiency of factor XI is often called hemophilia C.
| Descriptor ID |
D005172
|
| MeSH Number(s) |
D12.776.124.125.425 D23.119.425
|
| Concept/Terms |
Factor XI- Factor XI
- Factor Eleven
- Blood Coagulation Factor XI
- Plasma Thromboplastin Antecedent
- Antecedent, Plasma Thromboplastin
- Thromboplastin Antecedent, Plasma
- Coagulation Factor XI
- Factor XI, Coagulation
- Factor 11
|
Below are MeSH descriptors whose meaning is more general than "Factor XI".
Below are MeSH descriptors whose meaning is more specific than "Factor XI".
This graph shows the total number of publications written about "Factor XI" by people in this website by year, and whether "Factor XI" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Factor XI" by people in Profiles.
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Schmaier AH, Emsley J, Feener EP, Gailani D, Govers-Riemslag JWP, Kaplan AP, Maas C, Morrissey JH, Renné T, Sidelmann JJ, Meijers JCM. Nomenclature of factor XI and the contact system. J Thromb Haemost. 2019 12; 17(12):2216-2219.
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Brunnée T, La Porta C, Reddigari SR, Salerno VM, Kaplan AP, Silverberg M. Activation of factor XI in plasma is dependent on factor XII. Blood. 1993 Feb 01; 81(3):580-6.
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Kaplan AP, Ghebrehiwet B, Silverberg M, Sealey JE. The intrinsic coagulation-kinin pathway, complement cascades, plasma renin-angiotensin system, and their interrelationships. Crit Rev Immunol. 1981 Sep; 3(1):75-93.
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Silverberg M, Nicoll JE, Kaplan AP. The mechanism by which the light chain of cleaved HMW-kininogen augments the activation of prekallikrein, factor XI and Hageman factor. Thromb Res. 1980 Oct 15; 20(2):173-89.
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Mandle RJ, Kaplan AP. Hageman-factor-dependent fibrinolysis: generation of fibrinolytic activity by the interaction of human activated factor XI and plasminogen. Blood. 1979 Oct; 54(4):850-62.
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Thompson RE, Mandle R, Kaplan AP. Studies of binding of prekallikrein and Factor XI to high molecular weight kininogen and its light chain. Proc Natl Acad Sci U S A. 1979 Oct; 76(10):4862-6.
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Thompson RE, Mandle R, Kaplan AP. Association of factor XI and high molecular weight kininogen in human plasma. J Clin Invest. 1977 Dec; 60(6):1376-80.
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Meier HL, Pierce JV, Colman RW, Kaplan AP. Activation and function of human Hageman factor. The role of high molecular weight kininogen and prekallikrein. J Clin Invest. 1977 Jul; 60(1):18-31.
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Kaplan AP, Meier HL, Mandle R. The Hageman factor dependent pathways of coagulation, fibrinolysis, and kinin-generation. Semin Thromb Hemost. 1976 Jul; 3(1):1-26.
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Kaplan AP, Austen KF. Activation and control mechanisms of Hageman factor-dependent pathways of coagulation, fibrinolysis, and kinin generation and their contribution to the inflammatory response. J Allergy Clin Immunol. 1975 Dec; 56(6):491-506.