Hydroxyeicosatetraenoic Acids
"Hydroxyeicosatetraenoic Acids" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Eicosatetraenoic acids substituted in any position by one or more hydroxy groups. They are important intermediates in a series of biosynthetic processes leading from arachidonic acid to a number of biologically active compounds such as prostaglandins, thromboxanes, and leukotrienes.
| Descriptor ID |
D006893
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| MeSH Number(s) |
D10.251.355.255.100.300 D10.251.355.310.166.550
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Hydroxyeicosatetraenoic Acids".
Below are MeSH descriptors whose meaning is more specific than "Hydroxyeicosatetraenoic Acids".
This graph shows the total number of publications written about "Hydroxyeicosatetraenoic Acids" by people in this website by year, and whether "Hydroxyeicosatetraenoic Acids" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1995 | 1 | 0 | 1 |
| 2003 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 2 | 0 | 2 |
| 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Hydroxyeicosatetraenoic Acids" by people in Profiles.
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Zhang Y, Hoda MN, Zheng X, Li W, Luo P, Maddipati KR, Seki T, Ergul A, Wang MH. Combined therapy with COX-2 inhibitor and 20-HETE inhibitor reduces colon tumor growth and the adverse effects of ischemic stroke associated with COX-2 inhibition. Am J Physiol Regul Integr Comp Physiol. 2014 Sep 15; 307(6):R693-703.
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Eid S, Maalouf R, Jaffa AA, Nassif J, Hamdy A, Rashid A, Ziyadeh FN, Eid AA. 20-HETE and EETs in diabetic nephropathy: a novel mechanistic pathway. PLoS One. 2013; 8(8):e70029.
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Eid S, Abou-Kheir W, Sabra R, Daoud G, Jaffa A, Ziyadeh FN, Roman L, Eid AA. Involvement of renal cytochromes P450 and arachidonic acid metabolites in diabetic nephropathy. J Biol Regul Homeost Agents. 2013 Jul-Sep; 27(3):693-703.
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Silliman CC, Moore EE, Kelher MR, Khan SY, Gellar L, Elzi DJ. Identification of lipids that accumulate during the routine storage of prestorage leukoreduced red blood cells and cause acute lung injury. Transfusion. 2011 Dec; 51(12):2549-54.
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Lee SH, Rangiah K, Williams MV, Wehr AY, DuBois RN, Blair IA. Cyclooxygenase-2-mediated metabolism of arachidonic acid to 15-oxo-eicosatetraenoic acid by rat intestinal epithelial cells. Chem Res Toxicol. 2007 Nov; 20(11):1665-75.
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Lee SH, Williams MV, DuBois RN, Blair IA. Targeted lipidomics using electron capture atmospheric pressure chemical ionization mass spectrometry. Rapid Commun Mass Spectrom. 2003; 17(19):2168-76.
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Liu B, Khan WA, Hannun YA, Timar J, Taylor JD, Lundy S, Butovich I, Honn KV. 12(S)-hydroxyeicosatetraenoic acid and 13(S)-hydroxyoctadecadienoic acid regulation of protein kinase C-alpha in melanoma cells: role of receptor-mediated hydrolysis of inositol phospholipids. Proc Natl Acad Sci U S A. 1995 Sep 26; 92(20):9323-7.
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Liu B, Maher RJ, Hannun YA, Porter AT, Honn KV. 12(S)-HETE enhancement of prostate tumor cell invasion: selective role of PKC alpha. J Natl Cancer Inst. 1994 Aug 03; 86(15):1145-51.
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Setty BN, Werner MH, Hannun YA, Stuart MJ. 15-Hydroxyeicosatetraenoic acid-mediated potentiation of thrombin-induced platelet functions occurs via enhanced production of phosphoinositide-derived second messengers--sn-1,2-diacylglycerol and inositol-1,4,5-trisphosphate. Blood. 1992 Dec 01; 80(11):2765-73.