"Thiourea" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A photographic fixative used also in the manufacture of resins. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance may reasonably be anticipated to be a carcinogen (Merck Index, 9th ed). Many of its derivatives are ANTITHYROID AGENTS and/or FREE RADICAL SCAVENGERS.
| Descriptor ID |
D013890
|
| MeSH Number(s) |
D02.886.904 D02.948.898
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Thiourea".
Below are MeSH descriptors whose meaning is more specific than "Thiourea".
This graph shows the total number of publications written about "Thiourea" by people in this website by year, and whether "Thiourea" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 1 | 2 |
| 1999 | 1 | 0 | 1 |
| 2009 | 1 | 1 | 2 |
| 2010 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2015 | 2 | 1 | 3 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Thiourea" by people in Profiles.
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Wilson CL, Hung CF. Another Weapon in the Battle against Idiopathic Pulmonary Fibrosis? Am J Respir Cell Mol Biol. 2019 Apr; 60(4):386-387.
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Watkins D, Kumar S, Green KD, Arya DP, Garneau-Tsodikova S. Influence of linker length and composition on enzymatic activity and ribosomal binding of neomycin dimers. Antimicrob Agents Chemother. 2015 Jul; 59(7):3899-905.
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Nowotarski SL, Pachaiyappan B, Holshouser SL, Kutz CJ, Li Y, Huang Y, Sharma SK, Casero RA, Woster PM. Structure-activity study for (bis)ureidopropyl- and (bis)thioureidopropyldiamine LSD1 inhibitors with 3-5-3 and 3-6-3 carbon backbone architectures. Bioorg Med Chem. 2015 Apr 01; 23(7):1601-12.
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Verlinden BK, de Beer M, Pachaiyappan B, Besaans E, Andayi WA, Reader J, Niemand J, van Biljon R, Guy K, Egan T, Woster PM, Birkholtz LM. Interrogating alkyl and arylalkylpolyamino (bis)urea and (bis)thiourea isosteres as potent antimalarial chemotypes against multiple lifecycle forms of Plasmodium falciparum parasites. Bioorg Med Chem. 2015 Aug 15; 23(16):5131-43.
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Verlinden BK, Niemand J, Snyman J, Sharma SK, Beattie RJ, Woster PM, Birkholtz LM. Discovery of novel alkylated (bis)urea and (bis)thiourea polyamine analogues with potent antimalarial activities. J Med Chem. 2011 Oct 13; 54(19):6624-33.
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Sharma SK, Wu Y, Steinbergs N, Crowley ML, Hanson AS, Casero RA, Woster PM. (Bis)urea and (bis)thiourea inhibitors of lysine-specific demethylase 1 as epigenetic modulators. J Med Chem. 2010 Jul 22; 53(14):5197-212.
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Richards JJ, Reyes S, Stowe SD, Tucker AT, Ballard TE, Mathies LD, Cavanagh J, Melander C. Amide isosteres of oroidin: assessment of antibiofilm activity and C. elegans toxicity. J Med Chem. 2009 Aug 13; 52(15):4582-5.
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Xu L, Kappler CS, Mani SK, Shepherd NR, Renaud L, Snider P, Conway SJ, Menick DR. Chronic administration of KB-R7943 induces up-regulation of cardiac NCX1. J Biol Chem. 2009 Oct 02; 284(40):27265-72.
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Arya DP, Bruice TC. Triple-helix formation of DNA oligomers with methylthiourea-linked nucleosides (DNmt): a kinetic and thermodynamic analysis. Proc Natl Acad Sci U S A. 1999 Apr 13; 96(8):4384-9.
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D'Armini AM, Lemasters JJ, Egan TM. Studies of rat lung viability and adenine nucleotide metabolism after death. Ann Thorac Surg. 1996 Nov; 62(5):1448-53.