"TRPP Cation Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subgroup of TRP cation channels that are widely expressed in various cell types. Defects are associated with POLYCYSTIC KIDNEY DISEASES.
| Descriptor ID |
D050396
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| MeSH Number(s) |
D12.776.157.530.400.150.900 D12.776.157.530.400.901.777 D12.776.543.585.400.150.900 D12.776.543.585.400.901.777
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "TRPP Cation Channels".
Below are MeSH descriptors whose meaning is more specific than "TRPP Cation Channels".
This graph shows the total number of publications written about "TRPP Cation Channels" by people in this website by year, and whether "TRPP Cation Channels" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 2 | 0 | 2 |
| 2015 | 2 | 0 | 2 |
| 2017 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "TRPP Cation Channels" by people in Profiles.
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Recent advances in understanding ion transport mechanisms in polycystic kidney disease. Clin Sci (Lond). 2021 11 12; 135(21):2521-2540.
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Loss of primary cilia increases polycystin-2 and TRPV4 and the appearance of a nonselective cation channel in the mouse cortical collecting duct. Am J Physiol Renal Physiol. 2019 09 01; 317(3):F632-F637.
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Attenuation of accelerated renal cystogenesis in Pkd1 mice by renin-angiotensin system blockade. Am J Physiol Renal Physiol. 2018 02 01; 314(2):F210-F218.
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Suppressing angiotensinogen synthesis attenuates kidney cyst formation in a Pkd1 mouse model. FASEB J. 2016 Jan; 30(1):370-9.
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Molecular pathways and therapies in autosomal-dominant polycystic kidney disease. Physiology (Bethesda). 2015 May; 30(3):195-207.
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A Pkd1-Fbn1 genetic interaction implicates TGF-? signaling in the pathogenesis of vascular complications in autosomal dominant polycystic kidney disease. J Am Soc Nephrol. 2014 Jan; 25(1):81-91.
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TRPP2 and TRPV4 form an EGF-activated calcium permeable channel at the apical membrane of renal collecting duct cells. PLoS One. 2013; 8(8):e73424.
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G-protein signaling modulator 1 deficiency accelerates cystic disease in an orthologous mouse model of autosomal dominant polycystic kidney disease. Proc Natl Acad Sci U S A. 2012 Dec 26; 109(52):21462-7.
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The exocyst protein Sec10 interacts with Polycystin-2 and knockdown causes PKD-phenotypes. PLoS Genet. 2011 Apr; 7(4):e1001361.
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Loss of primary cilia results in deregulated and unabated apical calcium entry in ARPKD collecting duct cells. Am J Physiol Renal Physiol. 2006 Jun; 290(6):F1320-8.