"Codon, Nonsense" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An amino acid-specifying codon that has been converted to a stop codon (CODON, TERMINATOR) by mutation. Its occurance is abnormal causing premature termination of protein translation and results in production of truncated and non-functional proteins. A nonsense mutation is one that converts an amino acid-specific codon to a stop codon.
| Descriptor ID |
D018389
|
| MeSH Number(s) |
D13.444.735.544.355.250.235 G05.360.335.355.250.235 G05.365.590.195
|
| Concept/Terms |
Codon, Nonsense- Codon, Nonsense
- Premature Termination Codon
- Codon, Premature Termination
- Codons, Premature Termination
- Premature Termination Codons
- Termination Codon, Premature
- Termination Codons, Premature
- Premature Stop Codon
- Codon, Premature Stop
- Codons, Premature Stop
- Premature Stop Codons
- Stop Codon, Premature
- Stop Codons, Premature
- Nonsense Codon
- Codons, Nonsense
- Nonsense Codons
- Codon, Termination, Premature
Mutation, Nonsense- Mutation, Nonsense
- Mutations, Nonsense
- Nonsense Mutations
- Nonsense Mutation
Ochre Nonsense Codon- Ochre Nonsense Codon
- Codon, Ochre Nonsense
- Codons, Ochre Nonsense
- Nonsense Codon, Ochre
- Nonsense Codons, Ochre
- Ochre Nonsense Codons
Ochre Nonsense Mutation- Ochre Nonsense Mutation
- Mutation, Ochre Nonsense
- Mutations, Ochre Nonsense
- Nonsense Mutation, Ochre
- Nonsense Mutations, Ochre
- Ochre Nonsense Mutations
Amber Nonsense Mutation- Amber Nonsense Mutation
- Amber Nonsense Mutations
- Mutation, Amber Nonsense
- Mutations, Amber Nonsense
- Nonsense Mutation, Amber
- Nonsense Mutations, Amber
Opal Nonsense Mutation- Opal Nonsense Mutation
- Mutation, Opal Nonsense
- Mutations, Opal Nonsense
- Nonsense Mutation, Opal
- Nonsense Mutations, Opal
- Opal Nonsense Mutations
Amber Nonsense Codon- Amber Nonsense Codon
- Amber Nonsense Codons
- Codon, Amber Nonsense
- Codons, Amber Nonsense
- Nonsense Codons, Amber
- Nonsense Codon, Amber
Codon, Unassigned- Codon, Unassigned
- Codons, Unassigned
- Unassigned Codons
- Unassigned Codon
Opal Nonsense Codon- Opal Nonsense Codon
- Codon, Opal Nonsense
- Codons, Opal Nonsense
- Nonsense Codon, Opal
- Nonsense Codons, Opal
- Opal Nonsense Codons
|
Below are MeSH descriptors whose meaning is more general than "Codon, Nonsense".
Below are MeSH descriptors whose meaning is more specific than "Codon, Nonsense".
This graph shows the total number of publications written about "Codon, Nonsense" by people in this website by year, and whether "Codon, Nonsense" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2008 | 0 | 3 | 3 |
| 2009 | 0 | 2 | 2 |
| 2010 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Codon, Nonsense" by people in Profiles.
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Naked (N) mutant mice carry a nonsense mutation in the homeobox of Hoxc13. Exp Dermatol. 2022 03; 31(3):330-340.
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Glycogen Storage Disease Type IV Diagnosed at Fetal Autopsy. Pediatr Dev Pathol. 2020 Aug; 23(4):301-305.
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A Recurrent De Novo Nonsense Variant in ZSWIM6 Results in Severe Intellectual Disability without Frontonasal or Limb Malformations. Am J Hum Genet. 2017 Dec 07; 101(6):995-1005.
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Two cases of Vici syndrome associated with Idiopathic Thrombocytopenic Purpura (ITP) with a review of the literature. Am J Med Genet A. 2016 May; 170A(5):1343-6.
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Zebrafish model of tuberous sclerosis complex reveals cell-autonomous and non-cell-autonomous functions of mutant tuberin. Dis Model Mech. 2011 Mar; 4(2):255-67.
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De novo mutation in POLG leads to haplotype insufficiency and Alpers syndrome. Mitochondrion. 2009 Sep; 9(5):340-5.
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Frequent mutations in the MITF pathway in melanoma. Pigment Cell Melanoma Res. 2009 Aug; 22(4):435-44.
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DNA polymerase gamma and mitochondrial disease: understanding the consequence of POLG mutations. Biochim Biophys Acta. 2009 May; 1787(5):312-9.
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Two CES1 gene mutations lead to dysfunctional carboxylesterase 1 activity in man: clinical significance and molecular basis. Am J Hum Genet. 2008 Jun; 82(6):1241-8.
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Deleterious CHEK2 1100delC and L303X mutants identified among 38 human breast cancer cell lines. Breast Cancer Res Treat. 2009 Jan; 113(2):285-91.