"Proprotein Convertases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteolytic enzymes that are involved in the conversion of protein precursors such as peptide prohormones into PEPTIDE HORMONES. Some are ENDOPEPTIDASES, some are EXOPEPTIDASES.
| Descriptor ID |
D043484
|
| MeSH Number(s) |
D08.811.277.656.837
|
| Concept/Terms |
Proprotein Convertases- Proprotein Convertases
- Convertases, Proprotein
- Proprotein Convertase
- Convertase, Proprotein
Prohormone Convertases- Prohormone Convertases
- Convertases, Prohormone
- Prohormone Convertase
- Convertase, Prohormone
Subtilisin-Like Proprotein Convertases- Subtilisin-Like Proprotein Convertases
- Convertases, Subtilisin-Like Proprotein
- Proprotein Convertases, Subtilisin-Like
- Subtilisin Like Proprotein Convertases
Pro-Opiomelanocortin Converting Enzyme- Pro-Opiomelanocortin Converting Enzyme
- Converting Enzyme, Pro-Opiomelanocortin
- Pro Opiomelanocortin Converting Enzyme
- POMC Enzyme
- POMC-Converting Enzyme
- POMC Converting Enzyme
- Pro-Opiocortin Converting Protease
- Converting Protease, Pro-Opiocortin
- Pro Opiocortin Converting Protease
- Proopiomelanocortin Convertase
- Convertase, Proopiomelanocortin
- POMC Convertase
- Convertase, POMC
- Pro-Opiocortin Converting Enzyme
- Converting Enzyme, Pro-Opiocortin
- Pro Opiocortin Converting Enzyme
|
Below are MeSH descriptors whose meaning is more general than "Proprotein Convertases".
Below are MeSH descriptors whose meaning is more specific than "Proprotein Convertases".
This graph shows the total number of publications written about "Proprotein Convertases" by people in this website by year, and whether "Proprotein Convertases" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 2 | 0 | 2 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Proprotein Convertases" by people in Profiles.
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Precise regulation of the guidance receptor DMA-1 by KPC-1/Furin instructs dendritic branching decisions. Elife. 2016 Mar 14; 5.
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Local effects of human PCSK9 on the atherosclerotic lesion. J Pathol. 2016 Jan; 238(1):52-62.
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The effects of estrogen on serum level and hepatocyte expression of PCSK9. Metabolism. 2015 Apr; 64(4):554-60.
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Effect of alirocumab, a monoclonal antibody to PCSK9, on long-term cardiovascular outcomes following acute coronary syndromes: rationale and design of the ODYSSEY outcomes trial. Am Heart J. 2014 Nov; 168(5):682-9.
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Serum proprotein convertase subtilisin/kexin type 9 and cell surface low-density lipoprotein receptor: evidence for a reciprocal regulation. Circulation. 2013 Jun 18; 127(24):2403-13.
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Novel domain interaction regulates secretion of proprotein convertase subtilisin/kexin type 9 (PCSK9) protein. J Biol Chem. 2011 Dec 16; 286(50):43054-61.
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Self-association of human PCSK9 correlates with its LDLR-degrading activity. Biochemistry. 2008 Feb 12; 47(6):1631-9.
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Hydrophilic anilinogeranyl diphosphate prenyl analogues are Ras function inhibitors. Biochemistry. 2006 Dec 26; 45(51):15862-72.