Carboxylic Ester Hydrolases
"Carboxylic Ester Hydrolases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes which catalyze the hydrolysis of carboxylic acid esters with the formation of an alcohol and a carboxylic acid anion.
| Descriptor ID |
D002265
|
| MeSH Number(s) |
D08.811.277.352.100
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Carboxylic Ester Hydrolases".
Below are MeSH descriptors whose meaning is more specific than "Carboxylic Ester Hydrolases".
This graph shows the total number of publications written about "Carboxylic Ester Hydrolases" by people in this website by year, and whether "Carboxylic Ester Hydrolases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 1 | 2 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 1 | 2 |
| 2011 | 1 | 2 | 3 |
| 2013 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2021 | 0 | 2 | 2 |
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Below are the most recent publications written about "Carboxylic Ester Hydrolases" by people in Profiles.
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Plasma Carboxylesterase 1 Predicts Methylphenidate Exposure: A Proof-of-Concept Study Using Plasma Protein Biomarker for Hepatic Drug Metabolism. Clin Pharmacol Ther. 2022 04; 111(4):878-885.
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Decreased plasma rifapentine concentrations associated with AADAC single nucleotide polymorphism in adults with tuberculosis. J Antimicrob Chemother. 2021 02 11; 76(3):582-586.
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A Population Pharmacokinetic Analysis Shows that Arylacetamide Deacetylase (AADAC) Gene Polymorphism and HIV Infection Affect the Exposure of Rifapentine. Antimicrob Agents Chemother. 2019 04; 63(4).
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Integrated phenotypic and activity-based profiling links Ces3 to obesity and diabetes. Nat Chem Biol. 2014 Feb; 10(2):113-21.
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Prediction and in vitro evaluation of selected protease inhibitor antiviral drugs as inhibitors of carboxylesterase 1: a potential source of drug-drug interactions. Pharm Res. 2012 Apr; 29(4):972-82.
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Prolonged hepatomegaly in mice that cannot inactivate bacterial endotoxin. Hepatology. 2011 Sep 02; 54(3):1051-62.
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Fractionation of corn fiber treated by soaking in aqueous ammonia (SAA) for isolation of hemicellulose B and production of C5 sugars by enzyme hydrolysis. Appl Biochem Biotechnol. 2011 Aug; 164(8):1390-404.
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Vorinostat and sorafenib increase CD95 activation in gastrointestinal tumor cells through a Ca(2+)-de novo ceramide-PP2A-reactive oxygen species-dependent signaling pathway. Cancer Res. 2010 Aug 01; 70(15):6313-24.
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Identification of selected therapeutic agents as inhibitors of carboxylesterase 1: potential sources of metabolic drug interactions. Toxicology. 2010 Apr 11; 270(2-3):59-65.
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Prevention and reversal by cocaine esterase of cocaine-induced cardiovascular effects in rats. Drug Alcohol Depend. 2010 Jan 15; 106(2-3):219-29.