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Acetaminophen-induced hepatic injury: protective role of glutathione in man and rationale for therapy.

Acetaminophen-induced hepatic injury: protective role of glutathione in man and rationale for therapy. Clin Pharmacol Ther. 1974 Oct; 16(4):676-84.

View in: PubMed

subject areas
  • Acetaminophen
  • Acetylcysteine
  • Adult
  • Amobarbital
  • Animals
  • Chemical and Drug Induced Liver Injury
  • Chromatography, Paper
  • Cysteamine
  • Cytochrome P-450 Enzyme System
  • Desipramine
  • Dimercaprol
  • Dose-Response Relationship, Drug
  • Enzyme Induction
  • Female
  • Glutathione
  • Humans
  • Indicators and Reagents
  • Liver
  • Male
  • Mass Spectrometry
  • Methyltransferases
  • Mice
  • Microsomes, Liver
  • Phenobarbital
  • Protein Binding
  • Proteins
  • Sulfhydryl Compounds
  • Time Factors
  • Tritium

authors with profiles
  • David John Jollow