"Cysteamine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mercaptoethylamine compound that is endogenously derived from the COENZYME A degradative pathway. The fact that cysteamine is readily transported into LYSOSOMES where it reacts with CYSTINE to form cysteine-cysteamine disulfide and CYSTEINE has led to its use in CYSTINE DEPLETING AGENTS for the treatment of CYSTINOSIS.
| Descriptor ID |
D003543
|
| MeSH Number(s) |
D02.092.471.562.369 D02.886.489.472.369
|
| Concept/Terms |
Cysteamine- Cysteamine
- beta-Mercaptoethylamine
- beta Mercaptoethylamine
- Mercaptoethylamine
- Mercamine
- Mercaptamine
- 2-Aminoethanethiol
- 2 Aminoethanethiol
- Cysteinamine
Cysteamine Bitartrate- Cysteamine Bitartrate
- Bitartrate, Cysteamine
- Cysteamine Tartrate (1:1)
- Cysteamine Tartrate
- Tartrate, Cysteamine
|
Below are MeSH descriptors whose meaning is more general than "Cysteamine".
Below are MeSH descriptors whose meaning is more specific than "Cysteamine".
This graph shows the total number of publications written about "Cysteamine" by people in this website by year, and whether "Cysteamine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cysteamine" by people in Profiles.
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PEP-1-MsrA ameliorates inflammation and reduces atherosclerosis in apolipoprotein E deficient mice. J Transl Med. 2015 Sep 26; 13:316.
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Formation of free radicals and protein mixed disulfides in rat red cells exposed to dapsone hydroxylamine. Free Radic Biol Med. 1997; 22(7):1183-93.
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Acetaminophen hepatotoxicity: studies on the mechanism of cysteamine protection. Toxicol Appl Pharmacol. 1986 Mar 30; 83(1):115-25.
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Acetaminophen-induced hepatic injury: protective role of glutathione in man and rationale for therapy. Clin Pharmacol Ther. 1974 Oct; 16(4):676-84.