Structural Insights into the Interaction of Clinically Relevant Phosphorothioate mRNA Cap Analogs with Translation Initiation Factor 4E Reveal Stabilization via Electrostatic Thio-Effect.

Structural Insights into the Interaction of Clinically Relevant Phosphorothioate mRNA Cap Analogs with Translation Initiation Factor 4E Reveal Stabilization via Electrostatic Thio-Effect. ACS Chem Biol. 2021 02 19; 16(2):334-343.

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subject areas

Animals
Binding Sites
Cell Line
Crystallography, X-Ray
Eukaryotic Initiation Factor-4E
Mice
Nucleic Acid Conformation
Organoselenium Compounds
Phosphorothioate Oligonucleotides
Protein Binding
RNA Caps
Static Electricity
Stereoisomerism

authors with profiles

John D. Gross