Heterocyclic Compounds, 4 or More Rings
"Heterocyclic Compounds, 4 or More Rings" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of heterocyclic compounds that include four or more fused rings. Both aromatic or non-aromatic ring structures are included in this category.
Descriptor ID |
D006576
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MeSH Number(s) |
D03.633.400
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Concept/Terms |
Heterocyclic Compounds, 4 or More Rings- Heterocyclic Compounds, 4 or More Rings
- Heterocyclic Compounds with 4 or More Rings
- Heterocyclic Cpds, 4 or More Rings
- Heterocyclic Compounds with Four or More Rings
Heterocyclic Compounds, 5-Ring- Heterocyclic Compounds, 5-Ring
- 5-Ring Heterocyclic Compounds
- Heterocyclic Compounds, 5 Ring
- Heterocyclic Cpds, 5 Ring
- Five Ring Heterocyclic Compounds
- Fused Heterocyclic Compounds, Five-Ring
- Fused Heterocyclic Compounds, Five Ring
Heterocyclic Compounds, 4-Ring- Heterocyclic Compounds, 4-Ring
- 4-Ring Heterocyclic Compounds
- Heterocyclic Compounds, 4 Ring
- Heterocyclic Cpds, 4 Ring
- Four Ring Heterocyclic Compounds
- Fused Heterocyclic Compounds, Four-Ring
- Fused Heterocyclic Compounds, Four Ring
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Below are MeSH descriptors whose meaning is more general than "Heterocyclic Compounds, 4 or More Rings".
Below are MeSH descriptors whose meaning is more specific than "Heterocyclic Compounds, 4 or More Rings".
This graph shows the total number of publications written about "Heterocyclic Compounds, 4 or More Rings" by people in this website by year, and whether "Heterocyclic Compounds, 4 or More Rings" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2010 | 1 | 0 | 1 |
2011 | 2 | 0 | 2 |
2012 | 1 | 0 | 1 |
2013 | 3 | 0 | 3 |
2014 | 5 | 0 | 5 |
2015 | 3 | 0 | 3 |
2016 | 0 | 1 | 1 |
2017 | 0 | 1 | 1 |
2018 | 3 | 0 | 3 |
2019 | 1 | 2 | 3 |
2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Heterocyclic Compounds, 4 or More Rings" by people in Profiles.
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Ex vivo blockade of PI3K gamma or delta signaling enhances the antitumor potency of adoptively transferred CD8+ T cells. Eur J Immunol. 2020 09; 50(9):1386-1399.
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Co-formulated bictegravir, emtricitabine, and tenofovir alafenamide versus dolutegravir with emtricitabine and tenofovir alafenamide for initial treatment of HIV-1 infection: week 96 results from a randomised, double-blind, multicentre, phase 3, non-inferiority trial. Lancet HIV. 2019 06; 6(6):e364-e372.
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Mitochondrial Protease ClpP is a Target for the Anticancer Compounds ONC201 and Related Analogues. ACS Chem Biol. 2019 05 17; 14(5):1020-1029.
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NLRP3 inflammasome inhibition with MCC950 improves diabetes-mediated cognitive impairment and vasoneuronal remodeling after ischemia. Pharmacol Res. 2019 04; 142:237-250.
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Sofosbuvir/velpatasvir for chronic hepatitis C infection in patients with transfusion-dependent thalassemia. Am J Hematol. 2019 02; 94(2):E43-E45.
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Sparstolonin B (SsnB) attenuates liver fibrosis via a parallel conjugate pathway involving P53-P21 axis, TGF-beta signaling and focal adhesion that is TLR4 dependent. Eur J Pharmacol. 2018 Dec 15; 841:33-48.
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Efficacy of ONC201 in Desmoplastic Small Round Cell Tumor. Neoplasia. 2018 05; 20(5):524-532.
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Myosin-1 inhibition by PClP affects membrane shape, cortical actin distribution and lipid droplet dynamics in early Zebrafish embryos. PLoS One. 2017; 12(7):e0180301.
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Disassembly of myofibrils and potential imbalanced forces on Z-discs in cultured adult cardiomyocytes. Cytoskeleton (Hoboken). 2016 May; 73(5):246-57.
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Sparstolonin B attenuates early liver inflammation in experimental NASH by modulating TLR4 trafficking in lipid rafts via NADPH oxidase activation. Am J Physiol Gastrointest Liver Physiol. 2016 04 01; 310(7):G510-25.