GTP-Binding Protein beta Subunits
"GTP-Binding Protein beta Subunits" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Heterotrimeric GTP-binding protein subunits that tightly associate with GTP-BINDING PROTEIN GAMMA SUBUNITS. A dimer of beta and gamma subunits is formed when the GTP-BINDING PROTEIN ALPHA SUBUNIT dissociates from the GTP-binding protein heterotrimeric complex. The beta-gamma dimer can play an important role in signal transduction by interacting with a variety of second messengers.
| Descriptor ID |
D044387
|
| MeSH Number(s) |
D12.644.360.360.520 D12.776.157.325.332.520 D12.776.476.375.520 D12.776.543.325.450
|
| Concept/Terms |
GTP-Binding Protein beta Subunits- GTP-Binding Protein beta Subunits
- GTP Binding Protein beta Subunits
- G-Protein beta Subunit
- G Protein beta Subunit
- Subunit, G-Protein beta
- beta Subunit, G-Protein
- GTP-Binding Protein beta Subunit
- GTP Binding Protein beta Subunit
|
Below are MeSH descriptors whose meaning is more general than "GTP-Binding Protein beta Subunits".
Below are MeSH descriptors whose meaning is more specific than "GTP-Binding Protein beta Subunits".
This graph shows the total number of publications written about "GTP-Binding Protein beta Subunits" by people in this website by year, and whether "GTP-Binding Protein beta Subunits" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2005 | 2 | 0 | 2 |
| 2006 | 2 | 0 | 2 |
| 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "GTP-Binding Protein beta Subunits" by people in Profiles.
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Synthesis and assembly of G protein ?? dimers: comparison of in vitro and in vivo studies. Subcell Biochem. 2012; 63:155-80.
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Mechanistic pathways and biological roles for receptor-independent activators of G-protein signaling. Pharmacol Ther. 2007 Mar; 113(3):488-506.
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Role of the chaperonin CCT/TRiC complex in G protein betagamma-dimer assembly. J Biol Chem. 2006 Jul 21; 281(29):20221-32.
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G Protein betagamma dimer formation: Gbeta and Ggamma differentially determine efficiency of in vitro dimer formation. Biochemistry. 2005 Sep 06; 44(35):11882-90.
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Genomic analysis of G protein gamma subunits in human and mouse - the relationship between conserved gene structure and G protein betagamma dimer formation. Cell Signal. 2006 Feb; 18(2):194-201.
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Endothelin-1 activates endothelial cell nitric-oxide synthase via heterotrimeric G-protein betagamma subunit signaling to protein jinase B/Akt. J Biol Chem. 2003 Dec 12; 278(50):49929-35.
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Identification of Gbetagamma binding sites in the third intracellular loop of the M(3)-muscarinic receptor and their role in receptor regulation. J Biol Chem. 2000 Mar 24; 275(12):9026-34.