GTP-Binding Protein alpha Subunits
"GTP-Binding Protein alpha Subunits" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The GTPase-containing subunits of heterotrimeric GTP-binding proteins. When dissociated from the heterotrimeric complex these subunits interact with a variety of second messenger systems. Hydrolysis of GTP by the inherent GTPase activity of the subunit causes it to revert to its inactive (heterotrimeric) form. The GTP-Binding protein alpha subunits are grouped into families according to the type of action they have on second messenger systems.
| Descriptor ID |
D044385
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| MeSH Number(s) |
D08.811.277.040.330.300.200.100 D12.644.360.360.100 D12.776.157.325.332.100 D12.776.476.375.100 D12.776.543.325.100
|
| Concept/Terms |
GTP-Binding Protein alpha Subunits- GTP-Binding Protein alpha Subunits
- GTP Binding Protein alpha Subunits
- G-Protein alpha Subunit
- G Protein alpha Subunit
- alpha Subunit, G-Protein
- GTP-Binding Protein alpha Subunit
- GTP Binding Protein alpha Subunit
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Below are MeSH descriptors whose meaning is more general than "GTP-Binding Protein alpha Subunits".
Below are MeSH descriptors whose meaning is more specific than "GTP-Binding Protein alpha Subunits".
This graph shows the total number of publications written about "GTP-Binding Protein alpha Subunits" by people in this website by year, and whether "GTP-Binding Protein alpha Subunits" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2010 | 1 | 1 | 2 |
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Below are the most recent publications written about "GTP-Binding Protein alpha Subunits" by people in Profiles.
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Purification of heterotrimeric G protein alpha subunits by GST-Ric-8 association: primary characterization of purified G alpha(olf). J Biol Chem. 2011 Jan 28; 286(4):2625-35.
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Deletion of GRK1 causes retina degeneration through a transducin-independent mechanism. J Neurosci. 2010 Feb 17; 30(7):2496-503.
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The PDZ and band 4.1 containing protein Frmpd1 regulates the subcellular location of activator of G-protein signaling 3 and its interaction with G-proteins. J Biol Chem. 2008 Sep 05; 283(36):24718-28.
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Differential regulation of lipopolysaccharide and Gram-positive bacteria induced cytokine and chemokine production in macrophages by Galpha(i) proteins. Immunology. 2007 Sep; 122(1):116-23.
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Mechanistic pathways and biological roles for receptor-independent activators of G-protein signaling. Pharmacol Ther. 2007 Mar; 113(3):488-506.
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Downregulation of cone-specific gene expression and degeneration of cone photoreceptors in the Rpe65-/- mouse at early ages. Invest Ophthalmol Vis Sci. 2005 Apr; 46(4):1473-9.
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Asymmetrically distributed C. elegans homologs of AGS3/PINS control spindle position in the early embryo. Curr Biol. 2003 Jun 17; 13(12):1029-37.