"Chemokine CCL5" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A CC-type chemokine that is a chemoattractant for EOSINOPHILS; MONOCYTES; and LYMPHOCYTES. It is a potent and selective eosinophil chemotaxin that is stored in and released from PLATELETS and activated T-LYMPHOCYTES. Chemokine CCL5 is specific for CCR1 RECEPTORS; CCR3 RECEPTORS; and CCR5 RECEPTORS. The acronym RANTES refers to Regulated on Activation, Normal T Expressed and Secreted.
Descriptor ID |
D018946
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MeSH Number(s) |
D12.644.276.374.200.110.250 D12.776.467.374.200.110.250 D23.125.300.110.250 D23.469.200.110.250 D23.529.374.200.110.250
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Concept/Terms |
Chemokine CCL5- Chemokine CCL5
- CCL5, Chemokine
- RANTES Protein, T-Cell
- RANTES Protein, T Cell
- T-Cell RANTES Protein
- CCL5 Chemokine
- Chemokine, CCL5
- RANTES
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Below are MeSH descriptors whose meaning is more general than "Chemokine CCL5".
Below are MeSH descriptors whose meaning is more specific than "Chemokine CCL5".
This graph shows the total number of publications written about "Chemokine CCL5" by people in this website by year, and whether "Chemokine CCL5" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1996 | 0 | 2 | 2 |
1997 | 0 | 1 | 1 |
2000 | 0 | 1 | 1 |
2010 | 0 | 1 | 1 |
2011 | 1 | 0 | 1 |
2012 | 0 | 1 | 1 |
2013 | 1 | 0 | 1 |
2014 | 1 | 2 | 3 |
2015 | 0 | 2 | 2 |
2018 | 1 | 0 | 1 |
2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Chemokine CCL5" by people in Profiles.
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Combined MEK/PD-L1 Inhibition Alters Peripheral Cytokines and Lymphocyte Populations Correlating with Improved Clinical Outcomes in Advanced Biliary Tract Cancer. Clin Cancer Res. 2022 Oct 03; 28(19):4336-4345.
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Identification of an acid sphingomyelinase ceramide kinase pathway in the regulation of the chemokine CCL5. J Lipid Res. 2018 07; 59(7):1219-1229.
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Secreted protein acidic and rich in cysteine facilitates age-related cardiac inflammation and macrophage M1 polarization. Am J Physiol Cell Physiol. 2015 Jun 15; 308(12):C972-82.
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Vitamin D3 as a novel regulator of basic fibroblast growth factor in chronic rhinosinusitis with nasal polyposis. Int Forum Allergy Rhinol. 2015 Mar; 5(3):191-6.
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Regulation of prostate stromal fibroblasts by the PIM1 protein kinase. Cell Signal. 2015 Jan; 27(1):135-46.
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The Fli-1 transcription factor regulates the expression of CCL5/RANTES. J Immunol. 2014 Sep 15; 193(6):2661-8.
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Dysregulation in microRNA expression is associated with alterations in immune functions in combat veterans with post-traumatic stress disorder. PLoS One. 2014; 9(4):e94075.
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Sphingosine kinase 1 regulates tumor necrosis factor-mediated RANTES induction through p38 mitogen-activated protein kinase but independently of nuclear factor ?B activation. J Biol Chem. 2013 Sep 20; 288(38):27667-27679.
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Safety study of adeno-associated virus serotype 2-mediated human acid sphingomyelinase expression in the nonhuman primate brain. Hum Gene Ther. 2012 Aug; 23(8):891-902.
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Regulation of CC ligand 5/RANTES by acid sphingomyelinase and acid ceramidase. J Biol Chem. 2011 Apr 15; 286(15):13292-303.