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Singh, Avtar
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full name Avtar K. Singh
label Singh, Avtar
last name Singh
One or more keywords matched the following items that are connected to Singh, Avtar
Item TypeName
Academic Article Attenuation of renal ischemia/reperfusion injury by a triple drug combination therapy.
Academic Article Rho A negatively regulates cytokine-mediated inducible nitric oxide synthase expression in brain-derived transformed cell lines: negative regulation of IKKalpha.
Academic Article Potential targets of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor for multiple sclerosis therapy.
Academic Article 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside inhibits proinflammatory response in glial cells: a possible role of AMP-activated protein kinase.
Academic Article Regulation of gene expression associated with acute experimental autoimmune encephalomyelitis by Lovastatin.
Academic Article A novel role of lactosylceramide in the regulation of lipopolysaccharide/interferon-gamma-mediated inducible nitric oxide synthase gene expression: implications for neuroinflammatory diseases.
Academic Article Attenuation of ischemia-reperfusion injury in a canine model of autologous renal transplantation.
Academic Article N-acetylcysteine prevents endotoxin-induced degeneration of oligodendrocyte progenitors and hypomyelination in developing rat brain.
Academic Article Dual role of cAMP in iNOS expression in glial cells and macrophages is mediated by differential regulation of p38-MAPK/ATF-2 activation and iNOS stability.
Academic Article Adenosine kinase inhibitor attenuates the expression of inducible nitric oxide synthase in glial cells.
Academic Article A novel role of lactosylceramide in the regulation of tumor necrosis factor alpha-mediated proliferation of rat primary astrocytes. Implications for astrogliosis following neurotrauma.
Academic Article Involvement of phospholipase A2 and lipoxygenase in lipopolysaccharide-induced inducible nitric oxide synthase expression in glial cells.
Academic Article Peroxisomal participation in psychosine-mediated toxicity: implications for Krabbe's disease.
Academic Article 5-aminoimidazole-4-carboxamide ribonucleoside: a novel immunomodulator with therapeutic efficacy in experimental autoimmune encephalomyelitis.
Academic Article HMG-CoA reductase inhibitor augments survival and differentiation of oligodendrocyte progenitors in animal model of multiple sclerosis.
Academic Article The use of N-acetylcysteine for the prevention of hypertension in the reduced uterine perfusion pressure model for preeclampsia in Sprague-Dawley rats.
Academic Article 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside (AICAR) attenuates the expression of LPS- and Abeta peptide-induced inflammatory mediators in astroglia.
Academic Article 5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside inhibits cancer cell proliferation in vitro and in vivo via AMP-activated protein kinase.
Academic Article Cerebrovascular protection by various nitric oxide donors in rats after experimental stroke.
Academic Article Dysfunction of peroxisomes in twitcher mice brain: a possible mechanism of psychosine-induced disease.
Academic Article Combination of systemic hypothermia and N-acetylcysteine attenuates hypoxic-ischemic brain injury in neonatal rats.
Academic Article T-bet is essential for the progression of experimental autoimmune encephalomyelitis.
Academic Article Immunomodulatory effect of combination therapy with lovastatin and 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside alleviates neurodegeneration in experimental autoimmune encephalomyelitis.
Academic Article Post-trauma Lipitor treatment prevents endothelial dysfunction, facilitates neuroprotection, and promotes locomotor recovery following spinal cord injury.
Academic Article Caffeic acid phenethyl ester reduces neurovascular inflammation and protects rat brain following transient focal cerebral ischemia.
Academic Article Lactosylceramide: a lipid second messenger in neuroinflammatory disease.
Academic Article Combined medication of lovastatin with rolipram suppresses severity of experimental autoimmune encephalomyelitis.
Academic Article Peroxisomal dysfunction in inflammatory childhood white matter disorders: an unexpected contributor to neuropathology.
Academic Article Reduction of lipoxidative load by secretory phospholipase A2 inhibition protects against neurovascular injury following experimental stroke in rat.
Academic Article Factors that affect postnatal bone growth retardation in the twitcher murine model of Krabbe disease.
Academic Article Apoptotic positive cells in Krabbe brain and induction of apoptosis in rat C6 glial cells by psychosine.
Academic Article Stimulation of functional recovery via the mechanisms of neurorepair by S-nitrosoglutathione and motor exercise in a rat model of transient cerebral ischemia and reperfusion.
Academic Article Interference with RhoA-ROCK signaling mechanism in autoreactive CD4+ T cells enhances the bioavailability of 1,25-dihydroxyvitamin D3 in experimental autoimmune encephalomyelitis.
Academic Article The inhibitory effect of S-nitrosoglutathione on blood-brain barrier disruption and peroxynitrite formation in a rat model of experimental stroke.
Academic Article Combination therapy of N-acetylcysteine, sodium nitroprusside and phosphoramidon attenuates ischemia-reperfusion injury in rat kidney.
Academic Article N-Acetyl cysteine protects against injury in a rat model of focal cerebral ischemia.
Academic Article Modulation of Rho-Rock signaling pathway protects oligodendrocytes against cytokine toxicity via PPAR-a-dependent mechanism.
Academic Article The involvement of glucose metabolism in the regulation of inducible nitric oxide synthase gene expression in glial cells: possible role of glucose-6-phosphate dehydrogenase and CCAAT/enhancing binding protein.
Academic Article Molecular mechanism of psychosine-induced cell death in human oligodendrocyte cell line.
Academic Article Correlation of very long chain fatty acid accumulation and inflammatory disease progression in childhood X-ALD: implications for potential therapies.
Academic Article The role of neutral sphingomyelinase produced ceramide in lipopolysaccharide-mediated expression of inducible nitric oxide synthase.
Academic Article Administration of N-acetylcysteine after focal cerebral ischemia protects brain and reduces inflammation in a rat model of experimental stroke.
Academic Article Inflammatory mediator and beta-amyloid (25-35)-induced ceramide generation and iNOS expression are inhibited by vitamin E.
Academic Article Impaired peroxisomal function in the central nervous system with inflammatory disease of experimental autoimmune encephalomyelitis animals and protection by lovastatin treatment.
Academic Article The 15-deoxy-delta12,14-prostaglandin J2 inhibits the inflammatory response in primary rat astrocytes via down-regulating multiple steps in phosphatidylinositol 3-kinase-Akt-NF-kappaB-p300 pathway independent of peroxisome proliferator-activated receptor gamma.
Academic Article Attenuation of acute inflammatory response by atorvastatin after spinal cord injury in rats.
Academic Article S-Nitrosoglutathione reduces inflammation and protects brain against focal cerebral ischemia in a rat model of experimental stroke.
Academic Article Inhibition of phosphoinositide 3 kinase-Akt (protein kinase B)-nuclear factor-kappa B pathway by lovastatin limits endothelial-monocyte cell interaction.
Academic Article IL-4-induced peroxisome proliferator-activated receptor gamma activation inhibits NF-kappaB trans activation in central nervous system (CNS) glial cells and protects oligodendrocyte progenitors under neuroinflammatory disease conditions: implication for CNS-demyelinating diseases.
Academic Article GSNO attenuates EAE disease by S-nitrosylation-mediated modulation of endothelial-monocyte interactions.
Academic Article Modulation of peroxisome proliferator-activated receptor-alpha activity by N-acetyl cysteine attenuates inhibition of oligodendrocyte development in lipopolysaccharide stimulated mixed glial cultures.
Academic Article Inhibition of rho family functions by lovastatin promotes myelin repair in ameliorating experimental autoimmune encephalomyelitis.
Academic Article The role of AMPK in psychosine mediated effects on oligodendrocytes and astrocytes: implication for Krabbe disease.
Academic Article Lovastatin inhibits amyloid precursor protein (APP) beta-cleavage through reduction of APP distribution in Lubrol WX extractable low density lipid rafts.
Academic Article Lipopolysaccharide-induced peroxisomal dysfunction exacerbates cerebral white matter injury: attenuation by N-acetyl cysteine.
Academic Article Statin inhibits kainic acid-induced seizure and associated inflammation and hippocampal cell death.
Academic Article Psychosine-induced alterations in peroxisomes of twitcher mouse liver.
Academic Article Combination therapy of lovastatin and rolipram provides neuroprotection and promotes neurorepair in inflammatory demyelination model of multiple sclerosis.
Academic Article Administration of S-nitrosoglutathione after traumatic brain injury protects the neurovascular unit and reduces secondary injury in a rat model of controlled cortical impact.
Academic Article Activation of PPAR-? and PTEN cascade participates in lovastatin-mediated accelerated differentiation of oligodendrocyte progenitor cells.
Academic Article Involvement of AMP-activated-protein-kinase (AMPK) in neuronal amyloidogenesis.
Academic Article Synergistic activity of interleukin-17 and tumor necrosis factor-a enhances oxidative stress-mediated oligodendrocyte apoptosis.
Academic Article S-nitrosoglutathione reduces oxidative injury and promotes mechanisms of neurorepair following traumatic brain injury in rats.
Academic Article Protective role of S-nitrosoglutathione (GSNO) against cognitive impairment in rat model of chronic cerebral hypoperfusion.
Academic Article S-nitrosoglutathione induces ciliary neurotrophic factor expression in astrocytes, which has implications to protect the central nervous system under pathological conditions.
Academic Article Role of endogenous psychosine accumulation in oligodendrocyte differentiation and survival: implication for Krabbe disease.
Academic Article AMP-activated protein kinase signaling protects oligodendrocytes that restore central nervous system functions in an experimental autoimmune encephalomyelitis model.
Concept Drug Administration Schedule
Concept Central Nervous System
Concept Phospholipases A2, Secretory
Concept Synaptosomes
Concept RNA, Small Interfering
Concept Myelin Sheath
Concept Tumor Suppressor Protein p53
Concept Genes, MHC Class II
Concept Sensitivity and Specificity
Concept Cell Survival
Concept Receptors, Cell Surface
Concept Sphingomyelin Phosphodiesterase
Concept Amino Acid Sequence
Concept Drug Delivery Systems
Concept Stroke
Concept STAT3 Transcription Factor
Concept Synaptophysin
Concept E-Selectin
Concept T-Lymphocyte Subsets
Concept Sphingosine
Concept Nervous System Diseases
Concept Motor Skills
Concept Statistics, Nonparametric
Concept Seizures
Concept Growth Substances
Concept Organ Specificity
Concept Stem Cells
Concept Nitric Oxide Synthase
Concept Nervous System
Concept Organ Preservation Solutions
Concept Drug Synergism
Concept Signal Transduction
Concept Free Radical Scavengers
Concept Nitric Oxide Synthase Type III
Concept Severity of Illness Index
Concept Survival Rate
Concept MAP Kinase Signaling System
Concept Oxidative Stress
Concept Organ Size
Concept Spinal Cord
Concept S-Nitrosoglutathione
Concept Superoxide Dismutase
Concept Reactive Oxygen Species
Concept Sepsis
Concept Genes, Reporter
Concept Tetrazolium Salts
Concept Glycogen Synthase Kinase 3
Concept Protein Stability
Concept Second Messenger Systems
Concept Electrophoretic Mobility Shift Assay
Concept Carcinoma, Squamous Cell
Concept Case-Control Studies
Concept Mice, Inbred Strains
Concept Induced Pluripotent Stem Cells
Concept Sphingomyelins
Concept Extracellular Signal-Regulated MAP Kinases
Concept Nitric Oxide Synthase Type I
Concept Spleen
Concept Thiobarbituric Acid Reactive Substances
Concept Spinal Cord Injuries
Concept Multiple Sclerosis
Concept Nitric Oxide Synthase Type II
Concept Graft Survival
Concept Oligonucleotide Array Sequence Analysis
Concept Rats, Sprague-Dawley
Concept Central Nervous System Agents
Concept Steroid Hydroxylases
Concept Structure-Activity Relationship
Concept Superoxides
Concept Glutathione S-Transferase pi
Concept Base Sequence
Concept In Situ Nick-End Labeling
Concept Mice, Mutant Strains
Concept Molecular Sequence Data
Concept Hypoxia-Inducible Factor 1, alpha Subunit
Academic Article PPARa activation induces N(e)-Lys-acetylation of rat liver peroxisomal multifunctional enzyme type 1.
Academic Article STAT3 regulation by S-nitrosylation: implication for inflammatory disease.
Academic Article Effect of vitamin D3 intake on the onset of disease in a murine model of human Krabbe disease.
Academic Article S-Nitrosoglutathione protects the spinal bladder: novel therapeutic approach to post-spinal cord injury bladder remodeling.
Academic Article ABCD1 deletion-induced mitochondrial dysfunction is corrected by SAHA: implication for adrenoleukodystrophy.
Academic Article Role of S-nitrosoglutathione mediated mechanisms in tau hyper-phosphorylation.
Academic Article Promoting endothelial function by S-nitrosoglutathione through the HIF-1a/VEGF pathway stimulates neurorepair and functional recovery following experimental stroke in rats.
Academic Article Oral administration of cytosolic PLA2 inhibitor arachidonyl trifluoromethyl ketone ameliorates cauda equina compression injury in rats.
Academic Article Blocking a vicious cycle nNOS/peroxynitrite/AMPK by S-nitrosoglutathione: implication for stroke therapy.
Academic Article S-Nitrosoglutathione-mediated STAT3 regulation in efficacy of radiotherapy and cisplatin therapy in head and neck squamous cell carcinoma.
Academic Article S-nitrosoglutathione reduces tau hyper-phosphorylation and provides neuroprotection in rat model of chronic cerebral hypoperfusion.
Academic Article AKP-11 - A Novel S1P1 Agonist with Favorable Safety Profile Attenuates Experimental Autoimmune Encephalomyelitis in Rat Model of Multiple Sclerosis.
Academic Article Functional Characterization of IPSC-Derived Brain Cells as a Model for X-Linked Adrenoleukodystrophy.
Academic Article Targeting the nNOS/peroxynitrite/calpain system to confer neuroprotection and aid functional recovery in a mouse model of TBI.
Academic Article S-Nitrosoglutathione ameliorates acute renal dysfunction in a rat model of lipopolysaccharide-induced sepsis.
Academic Article Therapeutic potential of statins in multiple sclerosis: immune modulation, neuroprotection and neurorepair.
Academic Article Biochemical, cell biological, pathological, and therapeutic aspects of Krabbe's disease.
Academic Article An NO/GSNO-based Neuroregeneration Strategy for Stroke Therapy.
Academic Article GSNO promotes functional recovery in experimental TBI by stabilizing HIF-1a.
Academic Article STAT3 Regulation By S-Nitrosylation: Implication In Cancer.
Academic Article Regulation of STAT3 and NF-?B activations by S-nitrosylation in multiple myeloma.
Academic Article Hypoxia inducible factor-1 alpha stabilization for regenerative therapy in traumatic brain injury.
Academic Article Combination therapy of lovastatin and AMP-activated protein kinase activator improves mitochondrial and peroxisomal functions and clinical disease in experimental autoimmune encephalomyelitis model.
Academic Article S-nitrosoglutathione reductase (GSNOR) inhibitor as an immune modulator in experimental autoimmune encephalomyelitis.
Academic Article Pathology of nNOS-Expressing GABAergic Neurons in Mouse Model of Alzheimer's Disease.
Academic Article Regulation of IL-10 and IL-17 mediated experimental autoimmune encephalomyelitis by S-nitrosoglutathione.
Academic Article Combined treatment with GSNO and CAPE accelerates functional recovery via additive antioxidant activities in a mouse model of TBI.
Academic Article Amelioration of spinal cord injury in rats by blocking peroxynitrite/calpain activity.
Academic Article Regulation of endothelial barrier integrity by redox-dependent nitric oxide signaling: Implication in traumatic and inflammatory brain injuries.
Academic Article S-Nitrosoglutathione Mimics the Beneficial Activity of Endothelial Nitric Oxide Synthase-Derived Nitric Oxide in a Mouse Model of Stroke.
Academic Article GSNOR and ALDH2 alleviate traumatic spinal cord injury.
Academic Article Optical Pooled Screens in Human Cells.
Academic Article Targeting GSNOR for functional recovery in a middle-aged mouse model of stroke.
Concept Neural Stem Cells
Concept Endoplasmic Reticulum Stress
Concept CRISPR-Cas Systems
Concept Behavior Rating Scale
Concept Glycogen Synthase Kinase 3 beta
Concept Superoxide Dismutase-1
Academic Article Neuroprotective effects of Alda-1 mitigate spinal cord injury in mice: involvement of Alda-1-induced ALDH2 activation-mediated suppression of reactive aldehyde mechanisms.
Academic Article Regulation of B cell functions by S-nitrosoglutathione in the EAE model.
Academic Article Vascular and immunopathological role of Asymmetric Dimethylarginine (ADMA) in Experimental Autoimmune Encephalomyelitis.
Academic Article Chitooligosaccharide prevents vascular endothelial cell apoptosis by attenuation of endoplasmic reticulum stress via suppression of oxidative stress through Nrf2-SOD1 up-regulation.
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  • Nitrosoglutathione