Lauren Elizabeth Ball

Title
InstitutionMedical University of South Carolina
DepartmentCell and Molecular Pharmacology and Experimental Therapeutics
AddressP.O. Box MSC 509
CRI311
173 Ashley Ave.
Phone843-792-4513
Fax843-792-2475
ORCID ORCID Icon0000-0001-6780-1679 Additional info
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    Collapse Biography 
    Collapse education and training
    University of the South, Sewanee, TNBS05/1994Biochemistry
    Medical University of South Carolina, Charleston, SCPhD05/2003Pharmacology
    Medical University of South Carolina, Charleston, SCPost-Doctoral08/2006Endocrinology

    Collapse Overview 
    Collapse keywords
    Insulin Signaling; Insulin Receptor Substrates; IGF-1 Signaling; Mass Spectrometry; LC-MS/MS; Proteomics; O-GlcNAc Modification; O-GlcNAc Transferase; Phosphoproteomics; Orbitrap; Post-translational Modifications; Redox Signaling; Insulin Resistance; Diabetic Complications; Cancer

    Collapse Research 
    Collapse research activities and funding
    R21CA240148     (ANGEL, PEGGY M)Aug 1, 2019 - Jul 31, 2021
    NIH
    Enzymatic Tools for 2D Tissue Localized and Deeper Proteomic Sequencing of Cancer Stromal Proteins
    Role: Co-Investigator
    R01AI138511     (VASU, CHENTHAMARAKSHAN)Nov 6, 2018 - Oct 31, 2023
    NIH
    Role of microbiota-TLR7/8 Interaction in systemic lupus erythematosus
    Role: Co-Investigator
    S10OD025126     (BALL, LAUREN ELIZABETH)Aug 3, 2018 - Aug 2, 2019
    NIH
    Orbitrap Fusion Lumos ETD Mass Spectrometer
    Role Description: ThermoScientific Orbitrap Fusion Lumos Mass Spectrometer with ETD and UVPD. High End Shared Instrumentation Grant ($991,000) to purchase state-of-the-art LC-MS/MS-based proteomics instrumentation for the MUSC Mass Spectrometry Facility.
    Role: Principal Investigator
    R35GM126955     (LUTTRELL, LOUIS M)May 1, 2018 - Apr 30, 2023
    NIH
    Pharmacodynamics of Biased G Protein-Coupled Receptor Agonism
    Role: Co-Investigator
    R21DE025920     (PALANISAMY, VISWANATHAN)Jan 1, 2017 - Dec 31, 2018
    NIH
    Comprehensive Identification of FXR1 Targets Using pSILAC-BONCAT Proteomics
    Role: Co-Investigator
    S10OD010731     (BALL, LAUREN ELIZABETH)May 1, 2012 - Apr 30, 2013
    NIH
    Orbitrap Mass Spectrometer
    Role: Principal Investigator
    P20GM103542     (TEW, KENNETH D.)Sep 1, 2011 - Jul 31, 2021
    NIH
    South Carolina COBRE in Oxidants, Redox Balance and Stress Signaling
    Role Description: The goal of the Proteomics Core is to assist COBRE-funded junior investigators investigate signaling mechanisms underlying disease onset/progression; drug effects and resistance; and cellular/systemic metabolic regulation using LC-MS/MS-based quantitative proteomics.
    Role: Director, Mass Spectrometry Facility and Proteomics Core
    R01DE020925     (BALL, LAUREN ELIZABETH)Jul 1, 2010 - Jun 30, 2015
    NIH
    Regulation of IGF-1 and Insulin Signaling by O-GlcNAc Glycosylation
    Role: Principal Investigator
    R01DK073336     (LEMASTERS, JOHN J)Mar 20, 2007 - Aug 31, 2018
    NIH
    Mechanisms of I/R Injury to Hepatocytes
    Role: Co-Investigator, 2014-2016
    IRG-97-219-08     (REED, CAROLYN E)Jan 1, 2007 - Dec 31, 2008
    American Cancer Society
    Regulation of Growth Factor Signaling by O-GlcNAc Glycosylation
    Role: Pilot Project PI, 2007-2008
    W81XWH-07-1-0691     (EBLEN, SCOTT T)Jun 1, 2006 - May 31, 2010
    DOD/US ARMY
    Regulation of Senescence by p38 MAP Kinase in ErbB-2-Induced Breast Cancer
    Role: Co-Investigator
    3-2005-337     (BALL, LAUREN E)Jun 1, 2005 - Sep 1, 2006
    Juvenile Diabetes Research Foundation
    Role of the Hexosamine Pathway in Vascular Complications of Diabetes.
    Role Description: Post-Doctoral Fellowship
    Role: Principal Investigator
    5U24DE016508-02     (SLATE, ELIZABETH H)Sep 27, 2004 - Aug 31, 2008
    NIH
    Oral Health Research Infrastructure Development at MUSC
    Role Description: Start up funds for faculty recruitment.
    Role: Recruited Faculty, 2006
    P20RR017696     (KIRKWOOD, KEITH L)Sep 30, 2002 - Jul 31, 2013
    NIH
    South Carolina COBRE for Oral Health Research
    Role Description: The goal of this study is to detect and functionally evaluate the role of glucose-induced O-GlcNAc modification of insulin receptor substrate (IRS1) in diabetic complications including alveolar bone loss.
    Role: Sub-Project PI, 2008-2010
    R01DK055524     (LUTTRELL, LOUIS M)Sep 25, 1998 - Apr 30, 2018
    NIH
    Tyrosine Kinases in G Protein Mediated Signaling
    Role: Co-Investigator, 2014-2018
    9732152     (CROUCH, ROSALIE K)Jun 16, 1998 - May 31, 2000
    NSF Div of Biol Infrastructure
    REU Site in Cellular Signal Transduction
    Role Description: The goal of this study was to detect age-related post-translational modifications of an integral membrane water channel, Aquaporin 0, by LC-MS/MS during the course of aging and cataract development.
    Role: Pre-Doctoral Fellow, 1998-2000
    R01DK002001     (BUSE, MARIA G)May 1, 1978 - Feb 28, 2014
    NIH
    Factors that modify insulin action
    Role Description: The goal of Aim 2 (2009-2014) led by Dr. Ball is to test the hypothesis that O-GlcNAc modification of IRS1 attenuates hepatic insulin signaling.
    Role: Co-Investigator, 2009-2014
    T32HL007260     (MENICK, DONALD R.)Jul 1, 1977 - Jun 30, 2022
    NIH
    Training To Improve Cardiovascular Therapies
    Role Description: The goal of this study was to evaluate the role of O-GlcNAc Transferase (OGT), O-GlcNAcase (OGA), and protein O-GlcNAc modification in the development of diabetic complications.
    Role: Post-Doctoral Fellow, 2003-2004

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Zhang Z, Huang Z, Awad M, Elsalanty M, Cray J, Ball LE, Maynard JC, Burlingame AL, Zeng H, Mansky KC, Ruan HB. O-GlcNAc glycosylation orchestrates fate decision and niche function of bone marrow stromal progenitors. Elife. 2023 03 02; 12. PMID: 36861967; PMCID: PMC10032655.
      Citations:    Fields:    Translation:AnimalsCells
    2. Rigby RR, Williams LT, Mitchell LJ, Ball L, Hamilton K. Understanding dietary behaviour change after a diagnosis of diabetes: A qualitative investigation of adults with type 2 diabetes. PLoS One. 2022; 17(12):e0278984. PMID: 36508418.
      Citations:    Fields:    
    3. Liu L, Lin B, Yin S, Ball LE, Delaney JR, Long DT, Gan W. Arginine methylation of BRD4 by PRMT2/4 governs transcription and DNA repair. Sci Adv. 2022 Dec 09; 8(49):eadd8928. PMID: 36475791.
      Citations:    Fields:    Translation:HumansCells
    4. Kirkegaard A, Mitchell L, Ball L, Williams LT. Developing the EQUIPED approach to quality management using multi-grounded theory. Nutr Diet. 2022 Oct 24. PMID: 36278267.
      Citations:    Fields:    
    5. Heafala A, Mitchell LJ, Ball L. Informing care through lived experiences: perspectives of consumers and carers regarding dietetic care for eating disorders in Australia. Eat Weight Disord. 2022 Oct 21. PMID: 36269547.
      Citations:    Fields:    
    6. Hobby J, Crowley J, Barnes K, Mitchell L, Parkinson J, Ball L. Effectiveness of interventions to improve health behaviours of health professionals: a systematic review. BMJ Open. 2022 09 26; 12(9):e058955. PMID: 36167392; PMCID: PMC9516219.
      Citations:    Fields:    Translation:Humans
    7. Bartrim K, Moyle W, Rigby R, Ball L. Examining dietitians' knowledge, skills and attitudes regarding working with older adults in residential aged care facilities and home care services: An integrative review. J Hum Nutr Diet. 2023 02; 36(1):86-96. PMID: 35922141.
      Citations: 1     Fields:    Translation:Humans
    8. Asher KE, Somerville M, Doucet S, Luke A, Ball L, Dombrowski SU, Hickson M, Witherspoon R. Effectiveness of general practitioner-delivered nutrition care interventions on dietary and health outcomes in adults with diet-related chronic conditions: a systematic review protocol. JBI Evid Synth. 2022 08 01; 20(8):2055-2063. PMID: 35971203.
      Citations:    Fields:    Translation:Humans
    9. Kirkegaard A, Mitchell L, Ball L, Williams LT, Kirkegaard A, Mitchell L, Ball L, Williams LT. Developing the Quality in Nutrition Care Model for Dietitians (QUINCE-MOD) in primary care: A mixed-method survey of healthcare consumers and professionals. J Hum Nutr Diet. 2023 02; 36(1):311-322. PMID: 35822586.
      Citations: 1     Fields:    Translation:Humans
    10. Kirkegaard A, Ball L, Mitchell L, Williams LT, Kirkegaard A, Ball L, Mitchell L, Williams LT. A novel perspective of Australian primary care dietetics: Insights from an exploratory study using complex adaptive systems theory. Nutr Diet. 2022 09; 79(4):469-480. PMID: 35692187; PMCID: PMC9545103.
      Citations: 2     Fields:    Translation:Humans
    11. Kelly JT, Ahmadvand A, Snoswell C, Ball L, Kelly JT, Ahmadvand A, Snoswell C, Ball L. How have temporary Medicare telehealth item numbers impacted the use of dietetics services in primary care settings? Nutr Diet. 2022 09; 79(4):481-488. PMID: 35692189; PMCID: PMC9539970.
      Citations: 1     Fields:    Translation:Humans
    12. Kirkegaard A, Ball L, Mitchell L, Williams LT, Kirkegaard A, Ball L, Mitchell L, Williams LT. The Quality in Nutrition Care (QUINCE) model: development of a model based on Australian healthcare consumer perspectives. Fam Pract. 2022 05 28; 39(3):471-478. PMID: 34676397.
      Citations:    
    13. Rigby RR, Mitchell LJ, Hamilton K, Ball L, Williams LT, Rigby RR, Mitchell LJ, Hamilton K, Ball L, Williams LT. Analyzing Dietary Behaviors Self-reported by People With Diabetes Using a Behavior Change Technique Taxonomy. J Nutr Educ Behav. 2022 08; 54(8):753-763. PMID: 35644787.
      Citations:    Fields:    Translation:Humans
    14. Chakraborty P, Parikh RY, Choi S, Tran D, Gooz M, Hedley ZT, Kim DS, Pytel D, Kang I, Nadig SN, Beeson GC, Ball L, Mehrotra M, Wang H, Berto S, Palanisamy V, Li H, Chatterjee S, Rodriguez PC, Maldonado EN, Diehl JA, Gangaraju VK, Mehrotra S, Chakraborty P, Parikh RY, Choi S, Tran D, Gooz M, Hedley ZT, Kim DS, Pytel D, Kang I, Nadig SN, Beeson GC, Ball L, Mehrotra M, Wang H, Berto S, Palanisamy V, Li H, Chatterjee S, Rodriguez PC, Maldonado EN, Diehl JA, Gangaraju VK, Mehrotra S. Carbon Monoxide Activates PERK-Regulated Autophagy to Induce Immunometabolic Reprogramming and Boost Antitumor T-cell Function. Cancer Res. 2022 05 16; 82(10):1969-1990. PMID: 35404405; PMCID: PMC9117468.
      Citations: 4     Fields:    Translation:HumansCells
    15. Barnes KA, Szewczyk Z, Kelly JT, Campbell KL, Ball LE, Barnes KA, Szewczyk Z, Kelly JT, Campbell KL, Ball LE. How cost-effective is nutrition care delivered in primary healthcare settings? A systematic review of trial-based economic evaluations. Nutr Rev. 2022 05 09; 80(6):1480-1496. PMID: 34605888.
      Citations:    
    16. Hobby J, Parkinson J, Ball L, Hobby J, Parkinson J, Ball L. Exploring health professionals' perceptions of how their own diet influences their self-efficacy in providing nutrition care. Psychol Health. 2022 Apr 28; 1-16. PMID: 35484729.
      Citations:    Fields:    
    17. Darcy M, Parkinson J, Ball L, Norton L, Hobby J, Darcy M, Parkinson J, Ball L, Norton L, Hobby J. Multicomponent approaches to promoting healthy behaviours in people with Type 2 diabetes: an integrative review. Health Promot Int. 2022 Apr 19. PMID: 35437595.
      Citations: 1     Fields:    
    18. Barnett A, Ball L, Coppieters MW, Morris NR, Kendall E, Campbell KL, Barnett A, Ball L, Coppieters MW, Morris NR, Kendall E, Campbell KL. Patients' experiences with rehabilitation care: a qualitative study to inform patient-centred outcomes. Disabil Rehabil. 2023 04; 45(8):1307-1314. PMID: 35435101.
      Citations:    Fields:    Translation:Humans
    19. Somerville M, Ball L, Kirkegaard A, Williams LT, Somerville M, Ball L, Kirkegaard A, Williams LT. How do patients want to receive nutrition care? Qualitative findings from Australian health consumers. Aust J Prim Health. 2022 Feb; 28(1):33-39. PMID: 34911618.
      Citations:    
    20. Davidson AR, Kelly J, Ball L, Morgan M, Reidlinger DP, Davidson AR, Kelly J, Ball L, Morgan M, Reidlinger DP. What do patients experience? Interprofessional collaborative practice for chronic conditions in primary care: an integrative review. BMC Prim Care. 2022 Jan 14; 23(1):8. PMID: 35172731; PMCID: PMC8759162.
      Citations:    
    21. Wei H, Green E, Ball L, Fan H, Lee J, Strange C, Wang H, Wei H, Green E, Ball L, Fan H, Lee J, Strange C, Wang H. Proteomic Analysis of Exosomes Secreted from Human Alpha-1 Antitrypsin Overexpressing Mesenchymal Stromal Cells. Biology (Basel). 2021 Dec 21; 11(1). PMID: 35053007; PMCID: PMC8773149.
      Citations:    
    22. Kirkegaard A, Ball L, Mitchell L, Brickley B, Williams LT, Kirkegaard A, Ball L, Mitchell L, Brickley B, Williams LT. Quality improvement strategies enhance primary care dietetics: A systematic review and meta-analysis. J Hum Nutr Diet. 2022 06; 35(3):479-493. PMID: 34725871.
      Citations:    
    23. Gerassimovich YA, Miladinovski-Bangall SJ, Bridges KM, Boateng L, Ball LE, Valafar H, Nag A, Gerassimovich YA, Miladinovski-Bangall SJ, Bridges KM, Boateng L, Ball LE, Valafar H, Nag A. Proximity-dependent biotinylation detects associations between SARS coronavirus nonstructural protein 1 and stress granule-associated proteins. J Biol Chem. 2021 12; 297(6):101399. PMID: 34774526; PMCID: PMC8580555.
      Citations:    
    24. Ball L, Ball L. Where to from here? Nutrition and dietetics research into the future. Nutr Diet. 2021 11; 78(5):463-465. PMID: 34751493.
      Citations:    
    25. Burch E, Williams LT, Thalib L, Ball L, Burch E, Williams LT, Thalib L, Ball L. What happens to diet quality in people newly diagnosed with type 2 diabetes? The 3D case-series study. J Hum Nutr Diet. 2022 02; 35(1):191-201. PMID: 34694048.
      Citations:    
    26. Clark PW, Williams LT, Kirkegaard A, Brickley B, Ball L, Clark PW, Williams LT, Kirkegaard A, Brickley B, Ball L. Perceptions of private practice dietitians regarding the collection and use of outcomes data in primary healthcare practices: A qualitative study. J Hum Nutr Diet. 2022 02; 35(1):154-164. PMID: 34605085.
      Citations:    
    27. Rujchanarong D, Lefler J, Saunders JE, Pippin S, Spruill L, Bethard JR, Ball LE, Mehta AS, Drake RR, Ostrowski MC, Angel PM, Rujchanarong D, Lefler J, Saunders JE, Pippin S, Spruill L, Bethard JR, Ball LE, Mehta AS, Drake RR, Ostrowski MC, Angel PM. Defining the Tumor Microenvironment by Integration of Immunohistochemistry and Extracellular Matrix Targeted Imaging Mass Spectrometry. Cancers (Basel). 2021 Sep 01; 13(17). PMID: 34503228; PMCID: PMC8430776.
      Citations:    
    28. Ball LE, Agana B, Comte-Walters S, Rockey DC, Masur H, Kottilil S, Meissner EG, Ball LE, Agana B, Comte-Walters S, Rockey DC, Masur H, Kottilil S, Meissner EG. Hepatitis C virus treatment with direct-acting antivirals induces rapid changes in the hepatic proteome. J Viral Hepat. 2021 11; 28(11):1614-1623. PMID: 34379872; PMCID: PMC8530867.
      Citations:    
    29. Schuck PL, Ball LE, Stewart JA, Schuck PL, Ball LE, Stewart JA. The DNA-binding protein CST associates with the cohesin complex and promotes chromosome cohesion. J Biol Chem. 2021 09; 297(3):101026. PMID: 34339741; PMCID: PMC8390553.
      Citations:    
    30. Somerville M, Ball L, Chua D, Johnson T, Williams S, Williams LT, Somerville M, Ball L, Chua D, Johnson T, Williams S, Williams LT. How do healthcare providers support people with prediabetes to eat well? An in-depth, mixed-methods case study of provider practices. Aust J Gen Pract. 2021 07; 50(7):497-504. PMID: 34189552.
      Citations:    
    31. Heafala A, Ball L, Rayner J, Mitchell LJ. What role do dietitians have in providing nutrition care for eating disorder treatment? An integrative review. J Hum Nutr Diet. 2021 08; 34(4):724-735. PMID: 34031923.
      Citations:    
    32. Ball L, Kirkegaard A, Ball L, Kirkegaard A. Innovation at the Edge of Nutrition Education Research. Nutrients. 2021 Jun 11; 13(6). PMID: 34208265; PMCID: PMC8230806.
      Citations:    
    33. Yin S, Liu L, Brobbey C, Palanisamy V, Ball LE, Olsen SK, Ostrowski MC, Gan W, Yin S, Liu L, Brobbey C, Palanisamy V, Ball LE, Olsen SK, Ostrowski MC, Gan W. PRMT5-mediated arginine methylation activates AKT kinase to govern tumorigenesis. Nat Commun. 2021 06 08; 12(1):3444. PMID: 34103528; PMCID: PMC8187744.
      Citations:    
    34. Clift CL, Su YR, Bichell D, Jensen Smith HC, Bethard JR, Norris-Caneda K, Comte-Walters S, Ball LE, Hollingsworth MA, Mehta AS, Drake RR, Angel PM, Clift CL, Su YR, Bichell D, Jensen Smith HC, Bethard JR, Norris-Caneda K, Comte-Walters S, Ball LE, Hollingsworth MA, Mehta AS, Drake RR, Angel PM. Collagen fiber regulation in human pediatric aortic valve development and disease. Sci Rep. 2021 05 07; 11(1):9751. PMID: 33963260; PMCID: PMC8105334.
      Citations:    
    35. Ball L, Somerville M, Crowley J, Calleja Z, Barnes K, Ball L, Somerville M, Crowley J, Calleja Z, Barnes K. Providing food to patients in primary care to induce weight loss: a systematic literature review. BMJ Nutr Prev Health. 2021; 4(1):333-341. PMID: 34308141; PMCID: PMC8258096.
      Citations:    
    36. Brickley B, Williams LT, Morgan M, Ross A, Trigger K, Ball L, Brickley B, Williams LT, Morgan M, Ross A, Trigger K, Ball L. Putting patients first: development of a patient advocate and general practitioner-informed model of patient-centred care. BMC Health Serv Res. 2021 Mar 20; 21(1):261. PMID: 33743709; PMCID: PMC7981870.
      Citations:    
    37. Ball LE, Riley LJ, Hadasha W, Pfukwa R, Smith CJI, Dafforn TR, Klumperman B, Ball LE, Riley LJ, Hadasha W, Pfukwa R, Smith CJI, Dafforn TR, Klumperman B. Influence of DIBMA Polymer Length on Lipid Nanodisc Formation and Membrane Protein Extraction. Biomacromolecules. 2021 02 08; 22(2):763-772. PMID: 33373193.
      Citations:    
    38. Brickley B, Williams LT, Morgan M, Ross A, Trigger K, Ball L, Brickley B, Williams LT, Morgan M, Ross A, Trigger K, Ball L. Patient-centred care delivered by general practitioners: a qualitative investigation of the experiences and perceptions of patients and providers. BMJ Qual Saf. 2022 03; 31(3):191-198. PMID: 33303622.
      Citations:    
    39. Soler ZM, Schlosser RJ, Mulligan JK, Smith TL, Mace JC, Ramakrishan VR, Norris-Caneda K, Bethard JR, Ball LE, Soler ZM, Schlosser RJ, Mulligan JK, Smith TL, Mace JC, Ramakrishan VR, Norris-Caneda K, Bethard JR, Ball LE. Olfactory cleft mucus proteome in chronic rhinosinusitis: a case-control pilot study. Int Forum Allergy Rhinol. 2021 08; 11(8):1162-1176. PMID: 33275311; PMCID: PMC8670410.
      Citations:    
    40. Zhang J, Ye ZW, Chen W, Culpepper J, Jiang H, Ball LE, Mehrotra S, Blumental-Perry A, Tew KD, Townsend DM, Zhang J, Ye ZW, Chen W, Culpepper J, Jiang H, Ball LE, Mehrotra S, Blumental-Perry A, Tew KD, Townsend DM. Altered redox regulation and S-glutathionylation of BiP contribute to bortezomib resistance in multiple myeloma. Free Radic Biol Med. 2020 11 20; 160:755-767. PMID: 32937189; PMCID: PMC7704679.
      Citations:    
    41. Ball L, Sturgiss E, Ball L, Sturgiss E. Celebrating diversity and adaptability in academic primary care. Aust J Prim Health. 2020 08; 26(4):i-ii. PMID: 32762826.
      Citations:    
    42. Somerville M, Burch E, Ball L, Williams LT, Somerville M, Burch E, Ball L, Williams LT. 'I could have made those changes years earlier': experiences and characteristics associated with receiving a prediabetes diagnosis among individuals recently diagnosed with type 2 diabetes. Fam Pract. 2020 07 23; 37(3):382-389. PMID: 31776562.
      Citations:    
    43. Angel PM, Spruill L, Jefferson M, Bethard JR, Ball LE, Hughes-Halbert C, Drake RR, Angel PM, Spruill L, Jefferson M, Bethard JR, Ball LE, Hughes-Halbert C, Drake RR. Zonal regulation of collagen-type proteins and posttranslational modifications in prostatic benign and cancer tissues by imaging mass spectrometry. Prostate. 2020 09; 80(13):1071-1086. PMID: 32687633; PMCID: PMC7857723.
      Citations:    
    44. Burch E, Williams LT, Thalib L, Ball L, Burch E, Williams LT, Thalib L, Ball L. Short-term improvements in diet quality in people newly diagnosed with type 2 diabetes are associated with smoking status, physical activity and body mass index: the 3D case series study. Nutr Diabetes. 2020 07 13; 10(1):25. PMID: 32661234; PMCID: PMC7359342.
      Citations:    
    45. Zhang L, Townsend DM, Morris M, Maldonado EN, Jiang YL, Broome AM, Bethard JR, Ball LE, Tew KD, Zhang L, Townsend DM, Morris M, Maldonado EN, Jiang YL, Broome AM, Bethard JR, Ball LE, Tew KD. Voltage-Dependent Anion Channels Influence Cytotoxicity of ME-344, a Therapeutic Isoflavone. J Pharmacol Exp Ther. 2020 08; 374(2):308-318. PMID: 32546528; PMCID: PMC7372917.
      Citations:    
    46. Brickley B, Sladdin I, Williams LT, Morgan M, Ross A, Trigger K, Ball L, Brickley B, Sladdin I, Williams LT, Morgan M, Ross A, Trigger K, Ball L. A new model of patient-centred care for general practitioners: results of an integrative review. Fam Pract. 2020 03 25; 37(2):154-172. PMID: 31670759.
      Citations:    
    47. Angel PM, Bruner E, Bethard J, Clift CL, Ball L, Drake RR, Feghali-Bostwick C, Angel PM, Bruner E, Bethard J, Clift CL, Ball L, Drake RR, Feghali-Bostwick C. Extracellular matrix alterations in low-grade lung adenocarcinoma compared with normal lung tissue by imaging mass spectrometry. J Mass Spectrom. 2020 Apr; 55(4):e4450. PMID: 31654589; PMCID: PMC7145762.
      Citations:    
    48. Hurst KE, Lawrence KA, Robino RA, Ball LE, Chung D, Thaxton JE, Hurst KE, Lawrence KA, Robino RA, Ball LE, Chung D, Thaxton JE. Remodeling Translation Primes CD8+ T-cell Antitumor Immunity. Cancer Immunol Res. 2020 05; 8(5):587-595. PMID: 32075802.
      Citations:    
    49. Somerville M, Ball L, Sierra-Silvestre E, Williams LT, Somerville M, Ball L, Sierra-Silvestre E, Williams LT. Understanding the knowledge, attitudes and practices of providing and receiving nutrition care for prediabetes: an integrative review. Aust J Prim Health. 2019 Oct; 25(4):289-302. PMID: 31575387.
      Citations:    
    50. Kruyer A, Ball LE, Townsend DM, Kalivas PW, Uys JD, Kruyer A, Ball LE, Townsend DM, Kalivas PW, Uys JD. Post-translational S-glutathionylation of cofilin increases actin cycling during cocaine seeking. PLoS One. 2019; 14(9):e0223037. PMID: 31550273; PMCID: PMC6759170.
      Citations:    
    51. Zhang L, Zhang J, Ye Z, Manevich Y, Ball LE, Bethard JR, Jiang YL, Broome AM, Dalton AC, Wang GY, Townsend DM, Tew KD, Zhang L, Zhang J, Ye Z, Manevich Y, Ball LE, Bethard JR, Jiang YL, Broome AM, Dalton AC, Wang GY, Townsend DM, Tew KD. Isoflavone ME-344 Disrupts Redox Homeostasis and Mitochondrial Function by Targeting Heme Oxygenase 1. Cancer Res. 2019 08 15; 79(16):4072-4085. PMID: 31227482; PMCID: PMC6697583.
      Citations:    
    52. Chakraborty P, Chatterjee S, Kesarwani P, Thyagarajan K, Iamsawat S, Dalheim A, Nguyen H, Selvam SP, Nasarre P, Scurti G, Hardiman G, Maulik N, Ball L, Gangaraju V, Rubinstein MP, Klauber-DeMore N, Hill EG, Ogretmen B, Yu XZ, Nishimura MI, Mehrotra S, Chakraborty P, Chatterjee S, Kesarwani P, Thyagarajan K, Iamsawat S, Dalheim A, Nguyen H, Selvam SP, Nasarre P, Scurti G, Hardiman G, Maulik N, Ball L, Gangaraju V, Rubinstein MP, Klauber-DeMore N, Hill EG, Ogretmen B, Yu XZ, Nishimura MI, Mehrotra S. Thioredoxin-1 improves the immunometabolic phenotype of antitumor T cells. J Biol Chem. 2019 06 07; 294(23):9198-9212. PMID: 30971427; PMCID: PMC6556575.
      Citations:    
    53. Liu B, Salgado OC, Singh S, Hippen KL, Maynard JC, Burlingame AL, Ball LE, Blazar BR, Farrar MA, Hogquist KA, Ruan HB, Liu B, Salgado OC, Singh S, Hippen KL, Maynard JC, Burlingame AL, Ball LE, Blazar BR, Farrar MA, Hogquist KA, Ruan HB. The lineage stability and suppressive program of regulatory T cells require protein O-GlcNAcylation. Nat Commun. 2019 01 21; 10(1):354. PMID: 30664665; PMCID: PMC6341091.
      Citations:    
    54. Sladdin I, Chaboyer W, Ball L, Gillespie BM. Development and psychometric testing of a patient-reported inventory to measure patient-centred care in dietetic practice. Aust J Prim Health. 2019 Jan; 25(6):547-554. PMID: 31751520.
      Citations:    
    55. Angel PM, Schwamborn K, Comte-Walters S, Clift CL, Ball LE, Mehta AS, Drake RR, Angel PM, Schwamborn K, Comte-Walters S, Clift CL, Ball LE, Mehta AS, Drake RR. Extracellular Matrix Imaging of Breast Tissue Pathologies by MALDI-Imaging Mass Spectrometry. Proteomics Clin Appl. 2019 01; 13(1):e1700152. PMID: 30251340; PMCID: PMC6730639.
      Citations:    
    56. Zhang J, Ye ZW, Chen W, Manevich Y, Mehrotra S, Ball L, Janssen-Heininger Y, Tew KD, Townsend DM, Zhang J, Ye ZW, Chen W, Manevich Y, Mehrotra S, Ball L, Janssen-Heininger Y, Tew KD, Townsend DM. S-Glutathionylation of estrogen receptor a affects dendritic cell function. J Biol Chem. 2018 03 23; 293(12):4366-4380. PMID: 29374060; PMCID: PMC5868252.
      Citations:    
    57. Angel PM, Comte-Walters S, Ball LE, Talbot K, Mehta A, Brockbank KGM, Drake RR, Angel PM, Comte-Walters S, Ball LE, Talbot K, Mehta A, Brockbank KGM, Drake RR. Mapping Extracellular Matrix Proteins in Formalin-Fixed, Paraffin-Embedded Tissues by MALDI Imaging Mass Spectrometry. J Proteome Res. 2018 01 05; 17(1):635-646. PMID: 29161047; PMCID: PMC6637938.
      Citations:    
    58. Herr DJ, Baarine M, Aune SE, Li X, Ball LE, Lemasters JJ, Beeson CC, Chou JC, Menick DR, Herr DJ, Baarine M, Aune SE, Li X, Ball LE, Lemasters JJ, Beeson CC, Chou JC, Menick DR. HDAC1 localizes to the mitochondria of cardiac myocytes and contributes to early cardiac reperfusion injury. J Mol Cell Cardiol. 2018 01; 114:309-319. PMID: 29224834; PMCID: PMC5846104.
      Citations:    
    59. Chatterjee S, Daenthanasanmak A, Chakraborty P, Wyatt MW, Dhar P, Selvam SP, Fu J, Zhang J, Nguyen H, Kang I, Toth K, Al-Homrani M, Husain M, Beeson G, Ball L, Helke K, Husain S, Garrett-Mayer E, Hardiman G, Mehrotra M, Nishimura MI, Beeson CC, Bupp MG, Wu J, Ogretmen B, Paulos CM, Rathmell J, Yu XZ, Mehrotra S, Chatterjee S, Daenthanasanmak A, Chakraborty P, Wyatt MW, Dhar P, Selvam SP, Fu J, Zhang J, Nguyen H, Kang I, Toth K, Al-Homrani M, Husain M, Beeson G, Ball L, Helke K, Husain S, Garrett-Mayer E, Hardiman G, Mehrotra M, Nishimura MI, Beeson CC, Bupp MG, Wu J, Ogretmen B, Paulos CM, Rathmell J, Yu XZ, Mehrotra S. CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response. Cell Metab. 2018 01 09; 27(1):85-100.e8. PMID: 29129787; PMCID: PMC5837048.
      Citations:    
    60. Kim MJ, Vargas MR, Harlan BA, Killoy KM, Ball LE, Comte-Walters S, Gooz M, Yamamoto Y, Beckman JS, Barbeito L, Pehar M, Kim MJ, Vargas MR, Harlan BA, Killoy KM, Ball LE, Comte-Walters S, Gooz M, Yamamoto Y, Beckman JS, Barbeito L, Pehar M. Nitration and Glycation Turn Mature NGF into a Toxic Factor for Motor Neurons: A Role for p75NTR and RAGE Signaling in ALS. Antioxid Redox Signal. 2018 06 20; 28(18):1587-1602. PMID: 28537420; PMCID: PMC5962334.
      Citations:    
    61. Nimitvilai S, Uys JD, Woodward JJ, Randall PK, Ball LE, Williams RW, Jones BC, Lu L, Grant KA, Mulholland PJ, Nimitvilai S, Uys JD, Woodward JJ, Randall PK, Ball LE, Williams RW, Jones BC, Lu L, Grant KA, Mulholland PJ. Orbitofrontal Neuroadaptations and Cross-Species Synaptic Biomarkers in Heavy-Drinking Macaques. J Neurosci. 2017 03 29; 37(13):3646-3660. PMID: 28270566; PMCID: PMC5373140.
      Citations:    
    62. Wang X, Yuan ZF, Fan J, Karch KR, Ball LE, Denu JM, Garcia BA, Wang X, Yuan ZF, Fan J, Karch KR, Ball LE, Denu JM, Garcia BA. A Novel Quantitative Mass Spectrometry Platform for Determining Protein O-GlcNAcylation Dynamics. Mol Cell Proteomics. 2016 07; 15(7):2462-75. PMID: 27114449; PMCID: PMC4937517.
      Citations:    
    63. Song JH, Padi SK, Luevano LA, Minden MD, DeAngelo DJ, Hardiman G, Ball LE, Warfel NA, Kraft AS, Song JH, Padi SK, Luevano LA, Minden MD, DeAngelo DJ, Hardiman G, Ball LE, Warfel NA, Kraft AS. Insulin receptor substrate 1 is a substrate of the Pim protein kinases. Oncotarget. 2016 Apr 12; 7(15):20152-65. PMID: 26956053; PMCID: PMC4991444.
      Citations:    
    64. Pehar M, Ball LE, Sharma DR, Harlan BA, Comte-Walters S, Neely BA, Vargas MR, Pehar M, Ball LE, Sharma DR, Harlan BA, Comte-Walters S, Neely BA, Vargas MR. Changes in Protein Expression and Lysine Acetylation Induced by Decreased Glutathione Levels in Astrocytes. Mol Cell Proteomics. 2016 Feb; 15(2):493-505. PMID: 26486419; PMCID: PMC4739669.
      Citations:    
    65. Williams GR, Bethard JR, Berkaw MN, Nagel AK, Luttrell LM, Ball LE, Williams GR, Bethard JR, Berkaw MN, Nagel AK, Luttrell LM, Ball LE. Exploring G protein-coupled receptor signaling networks using SILAC-based phosphoproteomics. Methods. 2016 Jan 01; 92:36-50. PMID: 26160508; PMCID: PMC4696908.
      Citations:    
    66. Uys JD, McGuier NS, Gass JT, Griffin WC, Ball LE, Mulholland PJ, Uys JD, McGuier NS, Gass JT, Griffin WC, Ball LE, Mulholland PJ. Chronic intermittent ethanol exposure and withdrawal leads to adaptations in nucleus accumbens core postsynaptic density proteome and dendritic spines. Addict Biol. 2016 May; 21(3):560-74. PMID: 25787124; PMCID: PMC4573771.
      Citations:    
    67. Nagel AK, Ball LE, Nagel AK, Ball LE. Intracellular protein O-GlcNAc modification integrates nutrient status with transcriptional and metabolic regulation. Adv Cancer Res. 2015; 126:137-66. PMID: 25727147.
      Citations:    
    68. Drake RR, Ball L, Drake RR, Ball L. Unique to this volume is the subsequent focus of individual chapters on what is known about glycosylation in relation to specific organ sites of cancer. Preface. Adv Cancer Res. 2015; 126:xiii-xiv. PMID: 25727154.
      Citations:    
    69. Nagel AK, Ball LE, Nagel AK, Ball LE. O-GlcNAc modification of the runt-related transcription factor 2 (Runx2) links osteogenesis and nutrient metabolism in bone marrow mesenchymal stem cells. Mol Cell Proteomics. 2014 Dec; 13(12):3381-95. PMID: 25187572; PMCID: PMC4256491.
      Citations:    
    70. Nagel AK, Ball LE, Nagel AK, Ball LE. O-GlcNAc transferase and O-GlcNAcase: achieving target substrate specificity. Amino Acids. 2014 Oct; 46(10):2305-16. PMID: 25173736; PMCID: PMC4584397.
      Citations:    
    71. Hart GW, Ball LE, Hart GW, Ball LE. Post-translational modifications: a major focus for the future of proteomics. Mol Cell Proteomics. 2013 Dec; 12(12):3443. PMID: 24277940; PMCID: PMC3861697.
      Citations:    
    72. Leymarie N, Griffin PJ, Jonscher K, Kolarich D, Orlando R, McComb M, Zaia J, Aguilan J, Alley WR, Altmann F, Ball LE, Basumallick L, Bazemore-Walker CR, Behnken H, Blank MA, Brown KJ, Bunz SC, Cairo CW, Cipollo JF, Daneshfar R, Desaire H, Drake RR, Go EP, Goldman R, Gruber C, Halim A, Hathout Y, Hensbergen PJ, Horn DM, Hurum D, Jabs W, Larson G, Ly M, Mann BF, Marx K, Mechref Y, Meyer B, Möginger U, Neusüß C, Nilsson J, Novotny MV, Nyalwidhe JO, Packer NH, Pompach P, Reiz B, Resemann A, Rohrer JS, Ruthenbeck A, Sanda M, Schulz JM, Schweiger-Hufnagel U, Sihlbom C, Song E, Staples GO, Suckau D, Tang H, Thaysen-Andersen M, Viner RI, An Y, Valmu L, Wada Y, Watson M, Windwarder M, Whittal R, Wuhrer M, Zhu Y, Zou C, Leymarie N, Griffin PJ, Jonscher K, Kolarich D, Orlando R, McComb M, Zaia J, Aguilan J, Alley WR, Altmann F, Ball LE, Basumallick L, Bazemore-Walker CR, Behnken H, Blank MA, Brown KJ, Bunz SC, Cairo CW, Cipollo JF, Daneshfar R, Desaire H, Drake RR, Go EP, Goldman R, Gruber C, Halim A, Hathout Y, Hensbergen PJ, Horn DM, Hurum D, Jabs W, Larson G, Ly M, Mann BF, Marx K, Mechref Y, Meyer B, M?ginger U, Neus?? C, Nilsson J, Novotny MV, Nyalwidhe JO, Packer NH, Pompach P, Reiz B, Resemann A, Rohrer JS, Ruthenbeck A, Sanda M, Schulz JM, Schweiger-Hufnagel U, Sihlbom C, Song E, Staples GO, Suckau D, Tang H, Thaysen-Andersen M, Viner RI, An Y, Valmu L, Wada Y, Watson M, Windwarder M, Whittal R, Wuhrer M, Zhu Y, Zou C. Interlaboratory study on differential analysis of protein glycosylation by mass spectrometry: the ABRF glycoprotein research multi-institutional study 2012. Mol Cell Proteomics. 2013 Oct; 12(10):2935-51. PMID: 23764502; PMCID: PMC3790302.
      Citations:    
    73. Nagel AK, Schilling M, Comte-Walters S, Berkaw MN, Ball LE, Nagel AK, Schilling M, Comte-Walters S, Berkaw MN, Ball LE. Identification of O-linked N-acetylglucosamine (O-GlcNAc)-modified osteoblast proteins by electron transfer dissociation tandem mass spectrometry reveals proteins critical for bone formation. Mol Cell Proteomics. 2013 Apr; 12(4):945-55. PMID: 23443134; PMCID: PMC3617341.
      Citations:    
    74. Darley-Usmar VM, Ball LE, Chatham JC, Darley-Usmar VM, Ball LE, Chatham JC. Protein O-linked ?-N-acetylglucosamine: a novel effector of cardiomyocyte metabolism and function. J Mol Cell Cardiol. 2012 Mar; 52(3):538-49. PMID: 21878340; PMCID: PMC3928598.
      Citations:    
    75. Klein AL, Berkaw MN, Buse MG, Ball LE, Klein AL, Berkaw MN, Buse MG, Ball LE. O-linked N-acetylglucosamine modification of insulin receptor substrate-1 occurs in close proximity to multiple SH2 domain binding motifs. Mol Cell Proteomics. 2009 Dec; 8(12):2733-45. PMID: 19671924; PMCID: PMC2816021.
      Citations:    
    76. Robinson KA, Ball LE, Buse MG, Robinson KA, Ball LE, Buse MG. Reduction of O-GlcNAc protein modification does not prevent insulin resistance in 3T3-L1 adipocytes. Am J Physiol Endocrinol Metab. 2007 Mar; 292(3):E884-90. PMID: 17122093; PMCID: PMC2366901.
      Citations:    
    77. Ball LE, Berkaw MN, Buse MG, Ball LE, Berkaw MN, Buse MG. Identification of the major site of O-linked beta-N-acetylglucosamine modification in the C terminus of insulin receptor substrate-1. Mol Cell Proteomics. 2006 Feb; 5(2):313-23. PMID: 16244361; PMCID: PMC2435407.
      Citations:    
    78. Ervin LA, Ball LE, Crouch RK, Schey KL, Ervin LA, Ball LE, Crouch RK, Schey KL. Phosphorylation and glycosylation of bovine lens MP20. Invest Ophthalmol Vis Sci. 2005 Feb; 46(2):627-35. PMID: 15671292.
      Citations:    
    79. Ball LE, Garland DL, Crouch RK, Schey KL, Ball LE, Garland DL, Crouch RK, Schey KL. Post-translational modifications of aquaporin 0 (AQP0) in the normal human lens: spatial and temporal occurrence. Biochemistry. 2004 Aug 03; 43(30):9856-65. PMID: 15274640.
      Citations:    
    80. Ball LE, Little M, Nowak MW, Garland DL, Crouch RK, Schey KL, Ball LE, Little M, Nowak MW, Garland DL, Crouch RK, Schey KL. Water permeability of C-terminally truncated aquaporin 0 (AQP0 1-243) observed in the aging human lens. Invest Ophthalmol Vis Sci. 2003 Nov; 44(11):4820-8. PMID: 14578404.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    81. Ball LE, Oatis JE, Dharmasiri K, Busman M, Wang J, Cowden LB, Galijatovic A, Chen N, Crouch RK, Knapp DR, Ball LE, Oatis JE, Dharmasiri K, Busman M, Wang J, Cowden LB, Galijatovic A, Chen N, Crouch RK, Knapp DR. Mass spectrometric analysis of integral membrane proteins: application to complete mapping of bacteriorhodopsins and rhodopsin. Protein Sci. 1998 Mar; 7(3):758-64. PMID: 9541408; PMCID: PMC2143964.
      Citations: 11     Fields:    Translation:AnimalsCells
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