Yuri K. Peterson

Title
InstitutionMedical University of South Carolina
DepartmentCOP Drug Discovery and Biomedical Sciences - MUSC Campus
AddressP.O. Box MSC 139
DD405
Drug Discovery Building - 70 President St.
Phone843-876-2498
Fax843-792-1617
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Mills CM, Benton TZ, Pi?a I, Francis MJ, Reyes L, Dolloff NG, Peterson YK, Woster PM. Stimulation of natural killer cells with small molecule inhibitors of CD38 for the treatment of neuroblastoma. Chem Sci. 2023 Feb 22; 14(8):2168-2182. PMID: 36845935; PMCID: PMC9945084.
      Citations:    
    2. Janneh AH, Kassir MF, Atilgan FC, Lee HG, Sheridan M, Oleinik N, Szulc Z, Voelkel-Johnson C, Nguyen H, Li H, Peterson YK, Marangoni E, Saatci O, Sahin O, Lilly M, Atkinson C, Tomlinson S, Mehrotra S, Ogretmen B. Crosstalk between pro-survival sphingolipid metabolism and complement signaling induces inflammasome-mediated tumor metastasis. Cell Rep. 2022 12 06; 41(10):111742. PMID: 36476873; PMCID: PMC9791981.
      Citations:    Fields:    Translation:HumansAnimals
    3. Mills CM, Turner J, Pi?a IC, Garrabrant KA, Geerts D, Bachmann AS, Peterson YK, Woster PM. Synthesis and evaluation of small molecule inhibitors of LSD1 for use against MYCN-expressing neuroblastoma. Eur J Med Chem. 2022 Dec 15; 244:114818. PMID: 36223680.
      Citations:    Fields:    Translation:HumansCells
    4. Furbish AB, Alford AS, Burger P, Peterson YK, Murray-Stewart T, Casero RA, Woster PM. Identification and Characterization of Novel Small-Molecule SMOX Inhibitors. Med Sci (Basel). 2022 08 30; 10(3). PMID: 36135832; PMCID: PMC9504029.
      Citations: 1     Fields:    
    5. Beck TC, Springs K, Morningstar JE, Mills C, Stoddard A, Guo L, Moore K, Gensemer C, Biggs R, Petrucci T, Kwon J, Stayer K, Koren N, Dunne J, Fulmer D, Vohra A, Mai L, Dooley S, Weninger J, Peterson Y, Woster P, Dix TA, Norris RA, Beck TC, Springs K, Morningstar JE, Mills C, Stoddard A, Guo L, Moore K, Gensemer C, Biggs R, Petrucci T, Kwon J, Stayer K, Koren N, Dunne J, Fulmer D, Vohra A, Mai L, Dooley S, Weninger J, Peterson Y, Woster P, Dix TA, Norris RA. Application of Pharmacokinetic Prediction Platforms in the Design of Optimized Anti-Cancer Drugs. Molecules. 2022 Jun 08; 27(12). PMID: 35744803; PMCID: PMC9227314.
      Citations:    Fields:    
    6. Heslop KA, Burger P, Kappler C, Solanki AK, Gooz M, Peterson YK, Mills C, Benton T, Duncan SA, Woster PM, Maldonado EN, Heslop KA, Burger P, Kappler C, Solanki AK, Gooz M, Peterson YK, Mills C, Benton T, Duncan SA, Woster PM, Maldonado EN. Small molecules targeting the NADH-binding pocket of VDAC modulate mitochondrial metabolism in hepatocarcinoma cells. Biomed Pharmacother. 2022 Jun; 150:112928. PMID: 35447542; PMCID: PMC9400819.
      Citations: 1     Fields:    Translation:HumansCells
    7. Turner J, Muraoka A, Bedenbaugh M, Childress B, Pernot L, Wiencek M, Peterson YK, Turner J, Muraoka A, Bedenbaugh M, Childress B, Pernot L, Wiencek M, Peterson YK. The Chemical Relationship Among Beta-Lactam Antibiotics and Potential Impacts on Reactivity and Decomposition. Front Microbiol. 2022; 13:807955. PMID: 35401470; PMCID: PMC8988990.
      Citations: 1     
    8. Motamarry A, Wolfe AM, Ramajayam KK, Pattanaik S, Benton T, Peterson Y, Faridi P, Prakash P, Twombley K, Haemmerich D, Motamarry A, Wolfe AM, Ramajayam KK, Pattanaik S, Benton T, Peterson Y, Faridi P, Prakash P, Twombley K, Haemmerich D. Extracorporeal Removal of Thermosensitive Liposomal Doxorubicin from Systemic Circulation after Tumor Delivery to Reduce Toxicities. Cancers (Basel). 2022 Mar 04; 14(5). PMID: 35267630; PMCID: PMC8909191.
      Citations:    
    9. Benton TZ, Mills CM, Turner JM, Francis MJ, Solomon DJ, Burger PB, Peterson YK, Dolloff NG, Bachmann AS, Woster PM, Benton TZ, Mills CM, Turner JM, Francis MJ, Solomon DJ, Burger PB, Peterson YK, Dolloff NG, Bachmann AS, Woster PM. Selective targeting of CD38 hydrolase and cyclase activity as an approach to immunostimulation. RSC Adv. 2021 Oct 08; 11(53):33260-33270. PMID: 35497564; PMCID: PMC9042253.
      Citations: 1     
    10. Beeson C, Peterson YK, Perron N, Bandyopadhyay M, Nasarre C, Beeson G, Comer RF, Lindsey CC, Schnellmann RG, Rohrer B, Beeson C, Peterson YK, Perron N, Bandyopadhyay M, Nasarre C, Beeson G, Comer RF, Lindsey CC, Schnellmann RG, Rohrer B. Newly Identified Chemicals Preserve Mitochondrial Capacity and Decelerate Loss of Photoreceptor Cells in Murine Retinal Degeneration Models. J Ocul Pharmacol Ther. 2021 Jul-Aug; 37(6):367-378. PMID: 33945330; PMCID: PMC8328042.
      Citations:    
    11. Sullivan LS, Pelzer D, Rice A, Peterson YK, Sade RM, Townsend DM, Vaughan L, Nichols M, Zisk N, Sullivan LS, Pelzer D, Rice A, Peterson YK, Sade RM, Townsend DM, Vaughan L, Nichols M, Zisk N. Responsibility for Structural Racism in Medicine: Reflections and Recommendations from One Institution. Narrat Inq Bioeth. 2021; 11(2):221-229. PMID: 34840187.
      Citations:    
    12. Dimou A, Nasarre C, Peterson YK, Pagano R, Gooz M, Nasarre P, Drabkin HA, Armeson KE, Gibney BC, Gemmill RM, Denlinger CE, Dimou A, Nasarre C, Peterson YK, Pagano R, Gooz M, Nasarre P, Drabkin HA, Armeson KE, Gibney BC, Gemmill RM, Denlinger CE. Neuropilin-2b facilitates resistance to tyrosine kinase inhibitors in non-small cell lung cancer. J Thorac Cardiovasc Surg. 2021 08; 162(2):463-473. PMID: 32653291; PMCID: PMC9453694.
      Citations:    
    13. Li X, Jiang Y, Peterson YK, Xu T, Himes RA, Luo X, Yin G, Inks ES, Dolloff N, Halene S, Chan SSL, Chou CJ, Li X, Jiang Y, Peterson YK, Xu T, Himes RA, Luo X, Yin G, Inks ES, Dolloff N, Halene S, Chan SSL, Chou CJ. Design of Hydrazide-Bearing HDACIs Based on Panobinostat and Their p53 and FLT3-ITD Dependency in Antileukemia Activity. J Med Chem. 2020 05 28; 63(10):5501-5525. PMID: 32321249; PMCID: PMC7684764.
      Citations:    
    14. Garcia D, Nasarre P, Bonilla IV, Hilliard E, Peterson YK, Spruill L, Broome AM, Hill EG, Yustein JT, Mehrotra S, Klauber-DeMore N, Garcia D, Nasarre P, Bonilla IV, Hilliard E, Peterson YK, Spruill L, Broome AM, Hill EG, Yustein JT, Mehrotra S, Klauber-DeMore N. Development of a Novel Humanized Monoclonal Antibody to Secreted Frizzled-Related Protein-2 That Inhibits Triple-Negative Breast Cancer and Angiosarcoma Growth In Vivo. Ann Surg Oncol. 2019 Dec; 26(13):4782-4790. PMID: 31515721; PMCID: PMC8261905.
      Citations:    
    15. Cameron RB, Peterson YK, Beeson CC, Schnellmann RG, Cameron RB, Peterson YK, Beeson CC, Schnellmann RG. Author Correction: Structural and pharmacological basis for the induction of mitochondrial biogenesis by formoterol but not clenbuterol. Sci Rep. 2019 May 01; 9(1):6790. PMID: 31043635; PMCID: PMC6494870.
      Citations:    
    16. De Palma RM, Parnham SR, Li Y, Oaks JJ, Peterson YK, Szulc ZM, Roth BM, Xing Y, Ogretmen B, De Palma RM, Parnham SR, Li Y, Oaks JJ, Peterson YK, Szulc ZM, Roth BM, Xing Y, Ogretmen B. The NMR-based characterization of the FTY720-SET complex reveals an alternative mechanism for the attenuation of the inhibitory SET-PP2A interaction. FASEB J. 2019 06; 33(6):7647-7666. PMID: 30917007; PMCID: PMC6529350.
      Citations:    
    17. Holshouser S, Dunworth M, Murray-Stewart T, Peterson YK, Burger P, Kirkpatrick J, Chen HH, Casero RA, Woster PM, Holshouser S, Dunworth M, Murray-Stewart T, Peterson YK, Burger P, Kirkpatrick J, Chen HH, Casero RA, Woster PM. Dual inhibitors of LSD1 and spermine oxidase. Medchemcomm. 2019 May 01; 10(5):778-790. PMID: 31191868; PMCID: PMC6533887.
      Citations:    
    18. Nganga R, Oleinik N, Kim J, Selvam SP, De Palma R, Johnson KA, Parikh RY, Gangaraju V, Peterson Y, Dany M, Stahelin RV, Voelkel-Johnson C, Szulc ZM, Bieberich E, Ogretmen B, Nganga R, Oleinik N, Kim J, Selvam SP, De Palma R, Johnson KA, Parikh RY, Gangaraju V, Peterson Y, Dany M, Stahelin RV, Voelkel-Johnson C, Szulc ZM, Bieberich E, Ogretmen B. Receptor-interacting Ser/Thr kinase 1 (RIPK1) and myosin IIA-dependent ceramidosomes form membrane pores that mediate blebbing and necroptosis. J Biol Chem. 2019 01 11; 294(2):502-519. PMID: 30420430; PMCID: PMC6333879.
      Citations:    
    19. Crona DJ, Skol AD, Leppänen VM, Glubb DM, Etheridge AS, Hilliard E, Peña CE, Peterson YK, Klauber-DeMore N, Alitalo KK, Innocenti F, Crona DJ, Skol AD, Lepp?nen VM, Glubb DM, Etheridge AS, Hilliard E, Pe?a CE, Peterson YK, Klauber-DeMore N, Alitalo KK, Innocenti F. Genetic Variants of VEGFA and FLT4 Are Determinants of Survival in Renal Cell Carcinoma Patients Treated with Sorafenib. Cancer Res. 2019 01 01; 79(1):231-241. PMID: 30385613; PMCID: PMC6541205.
      Citations:    
    20. Li X, Peterson YK, Inks ES, Himes RA, Li J, Zhang Y, Kong X, Chou CJ, Li X, Peterson YK, Inks ES, Himes RA, Li J, Zhang Y, Kong X, Chou CJ. Class I HDAC Inhibitors Display Different Antitumor Mechanism in Leukemia and Prostatic Cancer Cells Depending on Their p53 Status. J Med Chem. 2018 03 22; 61(6):2589-2603. PMID: 29499113; PMCID: PMC5908721.
      Citations:    
    21. Qie S, Majumder M, Mackiewicz K, Howley BV, Peterson YK, Howe PH, Palanisamy V, Diehl JA, Qie S, Majumder M, Mackiewicz K, Howley BV, Peterson YK, Howe PH, Palanisamy V, Diehl JA. Fbxo4-mediated degradation of Fxr1 suppresses tumorigenesis in head and neck squamous cell carcinoma. Nat Commun. 2017 11 16; 8(1):1534. PMID: 29142209; PMCID: PMC5688124.
      Citations:    
    22. Cameron RB, Peterson YK, Beeson CC, Schnellmann RG, Cameron RB, Peterson YK, Beeson CC, Schnellmann RG. Structural and pharmacological basis for the induction of mitochondrial biogenesis by formoterol but not clenbuterol. Sci Rep. 2017 09 05; 7(1):10578. PMID: 28874749; PMCID: PMC5585315.
      Citations:    
    23. Peterson YK, Nasarre P, Bonilla IV, Hilliard E, Samples J, Morinelli TA, Hill EG, Klauber-DeMore N, Peterson YK, Nasarre P, Bonilla IV, Hilliard E, Samples J, Morinelli TA, Hill EG, Klauber-DeMore N. Frizzled-5: a high affinity receptor for secreted frizzled-related protein-2 activation of nuclear factor of activated T-cells c3 signaling to promote angiogenesis. Angiogenesis. 2017 Nov; 20(4):615-628. PMID: 28840375; PMCID: PMC5675522.
      Citations:    
    24. Peterson YK, Luttrell LM, Peterson YK, Luttrell LM. The Diverse Roles of Arrestin Scaffolds in G Protein-Coupled Receptor Signaling. Pharmacol Rev. 2017 07; 69(3):256-297. PMID: 28626043; PMCID: PMC5482185.
      Citations:    
    25. McClure JJ, Inks ES, Zhang C, Peterson YK, Li J, Chundru K, Lee B, Buchanan A, Miao S, Chou CJ, McClure JJ, Inks ES, Zhang C, Peterson YK, Li J, Chundru K, Lee B, Buchanan A, Miao S, Chou CJ. Comparison of the Deacylase and Deacetylase Activity of Zinc-Dependent HDACs. ACS Chem Biol. 2017 06 16; 12(6):1644-1655. PMID: 28459537; PMCID: PMC5567816.
      Citations:    
    26. McClure JJ, Zhang C, Inks ES, Peterson YK, Li J, Chou CJ, McClure JJ, Zhang C, Inks ES, Peterson YK, Li J, Chou CJ. Development of Allosteric Hydrazide-Containing Class I Histone Deacetylase Inhibitors for Use in Acute Myeloid Leukemia. J Med Chem. 2016 11 10; 59(21):9942-9959. PMID: 27754681; PMCID: PMC5260863.
      Citations:    
    27. Trager RE, Giblock P, Soltani S, Upadhyay AA, Rekapalli B, Peterson YK, Trager RE, Giblock P, Soltani S, Upadhyay AA, Rekapalli B, Peterson YK. Docking optimization, variance and promiscuity for large-scale drug-like chemical space using high performance computing architectures. Drug Discov Today. 2016 10; 21(10):1672-1680. PMID: 27352630.
      Citations:    
    28. Lee MH, Appleton KM, Strungs EG, Kwon JY, Morinelli TA, Peterson YK, Laporte SA, Luttrell LM, Lee MH, Appleton KM, Strungs EG, Kwon JY, Morinelli TA, Peterson YK, Laporte SA, Luttrell LM. The conformational signature of ?-arrestin2 predicts its trafficking and signalling functions. Nature. 2016 Mar 31; 531(7596):665-8. PMID: 27007854; PMCID: PMC4973468.
      Citations:    
    29. Panneer Selvam S, De Palma RM, Oaks JJ, Oleinik N, Peterson YK, Stahelin RV, Skordalakes E, Ponnusamy S, Garrett-Mayer E, Smith CD, Ogretmen B, Panneer Selvam S, De Palma RM, Oaks JJ, Oleinik N, Peterson YK, Stahelin RV, Skordalakes E, Ponnusamy S, Garrett-Mayer E, Smith CD, Ogretmen B. Binding of the sphingolipid S1P to hTERT stabilizes telomerase at the nuclear periphery by allosterically mimicking protein phosphorylation. Sci Signal. 2015 Jun 16; 8(381):ra58. PMID: 26082434; PMCID: PMC4492107.
      Citations:    
    30. Leonard AP, Cameron RB, Speiser JL, Wolf BJ, Peterson YK, Schnellmann RG, Beeson CC, Rohrer B, Leonard AP, Cameron RB, Speiser JL, Wolf BJ, Peterson YK, Schnellmann RG, Beeson CC, Rohrer B. Quantitative analysis of mitochondrial morphology and membrane potential in living cells using high-content imaging, machine learning, and morphological binning. Biochim Biophys Acta. 2015 Feb; 1853(2):348-60. PMID: 25447550; PMCID: PMC4289477.
      Citations:    
    31. Appleton KM, Bigham KJ, Lindsey CC, Hazard S, Lirjoni J, Parnham S, Hennig M, Peterson YK, Appleton KM, Bigham KJ, Lindsey CC, Hazard S, Lirjoni J, Parnham S, Hennig M, Peterson YK. Development of inhibitors of heterotrimeric Gai subunits. Bioorg Med Chem. 2014 Jul 01; 22(13):3423-34. PMID: 24818958; PMCID: PMC4103618.
      Citations:    
    32. Raymond JR, Appleton KM, Pierce JY, Peterson YK, Raymond JR, Appleton KM, Pierce JY, Peterson YK. Suppression of GNAI2 message in ovarian cancer. J Ovarian Res. 2014 Jan 14; 7:6. PMID: 24423449; PMCID: PMC3905280.
      Citations:    
    33. Peterson YK, Cameron RB, Wills LP, Trager RE, Lindsey CC, Beeson CC, Schnellmann RG, Peterson YK, Cameron RB, Wills LP, Trager RE, Lindsey CC, Beeson CC, Schnellmann RG. ?2-Adrenoceptor agonists in the regulation of mitochondrial biogenesis. Bioorg Med Chem Lett. 2013 Oct 01; 23(19):5376-81. PMID: 23954364; PMCID: PMC3987705.
      Citations:    
    34. Wills LP, Beeson GC, Trager RE, Lindsey CC, Beeson CC, Peterson YK, Schnellmann RG, Wills LP, Beeson GC, Trager RE, Lindsey CC, Beeson CC, Peterson YK, Schnellmann RG. High-throughput respirometric assay identifies predictive toxicophore of mitochondrial injury. Toxicol Appl Pharmacol. 2013 Oct 15; 272(2):490-502. PMID: 23811330; PMCID: PMC3987703.
      Citations:    
    35. Wilson PC, Lee MH, Appleton KM, El-Shewy HM, Morinelli TA, Peterson YK, Luttrell LM, Jaffa AA, Wilson PC, Lee MH, Appleton KM, El-Shewy HM, Morinelli TA, Peterson YK, Luttrell LM, Jaffa AA. The arrestin-selective angiotensin AT1 receptor agonist [Sar1,Ile4,Ile8]-AngII negatively regulates bradykinin B2 receptor signaling via AT1-B2 receptor heterodimers. J Biol Chem. 2013 Jun 28; 288(26):18872-84. PMID: 23661707; PMCID: PMC3696663.
      Citations:    
    36. Leonard AP, Appleton KM, Luttrell LM, Peterson YK, Leonard AP, Appleton KM, Luttrell LM, Peterson YK. A high-content, live-cell, and real-time approach to the quantitation of ligand-induced ?-Arrestin2 and Class A/Class B GPCR mobilization. Microsc Microanal. 2013 Feb; 19(1):150-70. PMID: 23351552; PMCID: PMC4169994.
      Citations:    
    37. Orr RK, Hoehn JL, Col NF, Appleton KM, Lee MH, Alele C, Alele C, Luttrell DK, Peterson YK, Morinelli TA, Luttrell LM. Biasing the parathyroid hormone receptor: relating in vitro ligand efficacy to in vivo biological activity. Methods Enzymol. 2013; 522:229-62. PMID: 23374189.
      Citations:    
    38. Saddoughi SA, Gencer S, Peterson YK, Ward KE, Mukhopadhyay A, Oaks J, Bielawski J, Szulc ZM, Thomas RJ, Selvam SP, Senkal CE, Garrett-Mayer E, De Palma RM, Fedarovich D, Liu A, Habib AA, Stahelin RV, Perrotti D, Ogretmen B, Saddoughi SA, Gencer S, Peterson YK, Ward KE, Mukhopadhyay A, Oaks J, Bielawski J, Szulc ZM, Thomas RJ, Selvam SP, Senkal CE, Garrett-Mayer E, De Palma RM, Fedarovich D, Liu A, Habib AA, Stahelin RV, Perrotti D, Ogretmen B. Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A-RIPK1-dependent necroptosis. EMBO Mol Med. 2013 01; 5(1):105-21. PMID: 23180565; PMCID: PMC3569657.
      Citations:    
    39. Sentelle RD, Senkal CE, Jiang W, Ponnusamy S, Gencer S, Selvam SP, Ramshesh VK, Peterson YK, Lemasters JJ, Szulc ZM, Bielawski J, Ogretmen B, Sentelle RD, Senkal CE, Jiang W, Ponnusamy S, Gencer S, Selvam SP, Ramshesh VK, Peterson YK, Lemasters JJ, Szulc ZM, Bielawski J, Ogretmen B. Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy. Nat Chem Biol. 2012 Oct; 8(10):831-8. PMID: 22922758; PMCID: PMC3689583.
      Citations:    
    40. Fedarovich A, Djordjevic KA, Swanson SM, Peterson YK, Nicholas RA, Davies C, Fedarovich A, Djordjevic KA, Swanson SM, Peterson YK, Nicholas RA, Davies C. High-throughput screening for novel inhibitors of Neisseria gonorrhoeae penicillin-binding protein 2. PLoS One. 2012; 7(9):e44918. PMID: 23049763; PMCID: PMC3458020.
      Citations:    
    41. Gao P, Peterson YK, Smith RA, Smith CD, Gao P, Peterson YK, Smith RA, Smith CD. Characterization of isoenzyme-selective inhibitors of human sphingosine kinases. PLoS One. 2012; 7(9):e44543. PMID: 22970244; PMCID: PMC3438171.
      Citations:    
    42. Perera MN, Lin SH, Peterson YK, Bielawska A, Szulc ZM, Bittman R, Colombini M, Perera MN, Lin SH, Peterson YK, Bielawska A, Szulc ZM, Bittman R, Colombini M. Bax and Bcl-xL exert their regulation on different sites of the ceramide channel. Biochem J. 2012 Jul 01; 445(1):81-91. PMID: 22494048.
      Citations:    
    43. Wills LP, Trager RE, Beeson GC, Lindsey CC, Peterson YK, Beeson CC, Schnellmann RG, Wills LP, Trager RE, Beeson GC, Lindsey CC, Peterson YK, Beeson CC, Schnellmann RG. The ?2-adrenoceptor agonist formoterol stimulates mitochondrial biogenesis. J Pharmacol Exp Ther. 2012 Jul; 342(1):106-18. PMID: 22490378; PMCID: PMC3383035.
      Citations:    
    44. Orr RK, Hoehn JL, Col NF, Rhoades JA, Peterson YK, Zhu HJ, Appel DI, Peloquin CA, Markowitz JS. Prediction and in vitro evaluation of selected protease inhibitor antiviral drugs as inhibitors of carboxylesterase 1: a potential source of drug-drug interactions. Pharm Res. 2012 Apr; 29(4):972-82. PMID: 22161308.
      Citations:    
    45. Zhu HJ, Appel DI, Peterson YK, Wang Z, Markowitz JS, Zhu HJ, Appel DI, Peterson YK, Wang Z, Markowitz JS. Identification of selected therapeutic agents as inhibitors of carboxylesterase 1: potential sources of metabolic drug interactions. Toxicology. 2010 Apr 11; 270(2-3):59-65. PMID: 20097249.
      Citations:    
    46. Peterson YK, Wang XS, Casey PJ, Tropsha A, Peterson YK, Wang XS, Casey PJ, Tropsha A. Discovery of geranylgeranyltransferase-I inhibitors with novel scaffolds by the means of quantitative structure-activity relationship modeling, virtual screening, and experimental validation. J Med Chem. 2009 Jul 23; 52(14):4210-20. PMID: 19537691; PMCID: PMC2726652.
      Citations:    
    47. Rao PV, Peterson YK, Inoue T, Casey PJ, Rao PV, Peterson YK, Inoue T, Casey PJ. Effects of pharmacologic inhibition of protein geranylgeranyltransferase type I on aqueous humor outflow through the trabecular meshwork. Invest Ophthalmol Vis Sci. 2008 Jun; 49(6):2464-71. PMID: 18316706; PMCID: PMC2561264.
      Citations:    
    48. Baron RA, Peterson YK, Otto JC, Rudolph J, Casey PJ, Baron RA, Peterson YK, Otto JC, Rudolph J, Casey PJ. Time-dependent inhibition of isoprenylcysteine carboxyl methyltransferase by indole-based small molecules. Biochemistry. 2007 Jan 16; 46(2):554-60. PMID: 17209565.
      Citations:    
    49. Roberts MJ, Troutman JM, Chehade KA, Cha HC, Kao JP, Huang X, Zhan CG, Peterson YK, Subramanian T, Kamalakkannan S, Andres DA, Spielmann HP, Roberts MJ, Troutman JM, Chehade KA, Cha HC, Kao JP, Huang X, Zhan CG, Peterson YK, Subramanian T, Kamalakkannan S, Andres DA, Spielmann HP. Hydrophilic anilinogeranyl diphosphate prenyl analogues are Ras function inhibitors. Biochemistry. 2006 Dec 26; 45(51):15862-72. PMID: 17176109.
      Citations:    
    50. Song KS, Peterson YK, Freidman A, Blumer JB, Sato M, Lanier SM, Song KS, Peterson YK, Freidman A, Blumer JB, Sato M, Lanier SM. Identification and characterization of a G-protein regulatory motif in WAVE1. FEBS Lett. 2006 Apr 03; 580(8):1993-8. PMID: 16530190.
      Citations:    
    51. Peterson YK, Kelly P, Weinbaum CA, Casey PJ, Peterson YK, Kelly P, Weinbaum CA, Casey PJ. A novel protein geranylgeranyltransferase-I inhibitor with high potency, selectivity, and cellular activity. J Biol Chem. 2006 May 05; 281(18):12445-50. PMID: 16517596.
      Citations:    
    52. Bowers MS, McFarland K, Lake RW, Peterson YK, Lapish CC, Gregory ML, Lanier SM, Kalivas PW, Bowers MS, McFarland K, Lake RW, Peterson YK, Lapish CC, Gregory ML, Lanier SM, Kalivas PW. Activator of G protein signaling 3: a gatekeeper of cocaine sensitization and drug seeking. Neuron. 2004 Apr 22; 42(2):269-81. PMID: 15091342; PMCID: PMC3619420.
      Citations:    
    53. Ghosh M, Peterson YK, Lanier SM, Smrcka AV, Ghosh M, Peterson YK, Lanier SM, Smrcka AV. Receptor- and nucleotide exchange-independent mechanisms for promoting G protein subunit dissociation. J Biol Chem. 2003 Sep 12; 278(37):34747-50. PMID: 12881533.
      Citations: 27     Fields:    Translation:AnimalsCells
    54. Ma H, Peterson YK, Bernard ML, Lanier SM, Graber SG, Ma H, Peterson YK, Bernard ML, Lanier SM, Graber SG. Influence of cytosolic AGS3 on receptor--G protein coupling. Biochemistry. 2003 Jul 08; 42(26):8085-93. PMID: 12834360.
      Citations: 4     Fields:    Translation:AnimalsCells
    55. Gotta M, Dong Y, Peterson YK, Lanier SM, Ahringer J, Gotta M, Dong Y, Peterson YK, Lanier SM, Ahringer J. Asymmetrically distributed C. elegans homologs of AGS3/PINS control spindle position in the early embryo. Curr Biol. 2003 Jun 17; 13(12):1029-37. PMID: 12814548.
      Citations: 100     Fields:    Translation:AnimalsCells
    56. Blumer JB, Bernard ML, Peterson YK, Nezu J, Chung P, Dunican DJ, Knoblich JA, Lanier SM, Blumer JB, Bernard ML, Peterson YK, Nezu J, Chung P, Dunican DJ, Knoblich JA, Lanier SM. Interaction of activator of G-protein signaling 3 (AGS3) with LKB1, a serine/threonine kinase involved in cell polarity and cell cycle progression: phosphorylation of the G-protein regulatory (GPR) motif as a regulatory mechanism for the interaction of GPR motifs with Gi alpha. J Biol Chem. 2003 Jun 27; 278(26):23217-20. PMID: 12719437.
      Citations: 25     Fields:    Translation:AnimalsCells
    57. Peterson YK, Hazard S, Graber SG, Lanier SM, Peterson YK, Hazard S, Graber SG, Lanier SM. Identification of structural features in the G-protein regulatory motif required for regulation of heterotrimeric G-proteins. J Biol Chem. 2002 Mar 01; 277(9):6767-70. PMID: 11756403.
      Citations: 20     Fields:    Translation:AnimalsCells
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