p38 Mitogen-Activated Protein Kinases
                             
                            
                            
                                
                            
                            
                                
                            
                            
                            
                                
                                    
                                            
	"p38 Mitogen-Activated Protein Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
	
	
		
			
			
				A mitogen-activated protein kinase subfamily that regulates a variety of cellular processes including CELL GROWTH PROCESSES; CELL DIFFERENTIATION; APOPTOSIS; and cellular responses to INFLAMMATION. The P38 MAP kinases are regulated by CYTOKINE RECEPTORS and can be activated in response to bacterial pathogens.
    
			
			
				
				
					
						| Descriptor ID | D048051 | 
					
						| MeSH Number(s) | D08.811.913.696.620.682.700.567.843 D12.644.360.450.835 D12.776.476.450.835 | 
					
						| Concept/Terms | p38 Mitogen-Activated Protein Kinasesp38 Mitogen-Activated Protein Kinasesp38 Mitogen Activated Protein Kinasesp38 MAP KinaseMAP Kinase, p38p38 MAPKMAPK, p38p38 SAPKMitogen-Activated Protein Kinase p38Mitogen Activated Protein Kinase p38p38 Protein KinaseProtein Kinase, p38
 | 
					
				
			 
			
				Below are MeSH descriptors whose meaning is more general than "p38 Mitogen-Activated Protein Kinases".
				
			 
			
			
				Below are MeSH descriptors whose meaning is more specific than "p38 Mitogen-Activated Protein Kinases".
				
			 
		 
	 
 
                                        
                                            
	
	
		
			
			
					
				This graph shows the total number of publications written about "p38 Mitogen-Activated Protein Kinases" by people in this website by year, and whether "p38 Mitogen-Activated Protein Kinases" was a major or minor topic of these publications. 
				
					 
                    To see the data from this visualization as text, 
click here. 
                
		            | Year | Major Topic | Minor Topic | Total | 
|---|
| 1996 | 0 | 1 | 1 | 
| 1997 | 0 | 1 | 1 | 
| 1998 | 0 | 4 | 4 | 
| 1999 | 0 | 2 | 2 | 
| 2000 | 0 | 3 | 3 | 
| 2001 | 0 | 3 | 3 | 
| 2002 | 0 | 2 | 2 | 
| 2003 | 0 | 1 | 1 | 
| 2004 | 1 | 3 | 4 | 
| 2005 | 3 | 4 | 7 | 
| 2006 | 3 | 3 | 6 | 
| 2007 | 4 | 3 | 7 | 
| 2008 | 0 | 4 | 4 | 
| 2009 | 2 | 6 | 8 | 
| 2010 | 1 | 1 | 2 | 
| 2011 | 3 | 3 | 6 | 
| 2012 | 2 | 3 | 5 | 
| 2013 | 3 | 4 | 7 | 
| 2014 | 1 | 4 | 5 | 
| 2015 | 1 | 1 | 2 | 
| 2016 | 1 | 1 | 2 | 
| 2017 | 0 | 1 | 1 | 
| 2021 | 0 | 1 | 1 | 
| 2022 | 0 | 1 | 1 | 
                    To return to the timeline, 
click here.
                 
			 	
			
			
			
			
				Below are the most recent publications written about "p38 Mitogen-Activated Protein Kinases" by people in Profiles.
						
					
								- 
								p38 MAPK Is a Major Regulator of Amyloid Beta-Induced IL-6 Expression in Human Microglia. Mol Neurobiol. 2022 Sep; 59(9):5284-5298. 
- 
								Effects of emodin, a plant-derived anthraquinone, on TGF-?1-induced cardiac fibroblast activation and function. J Cell Physiol. 2021 11; 236(11):7440-7449. 
- 
								High-content screening assay-based discovery of paullones as novel podocyte-protective agents. Am J Physiol Renal Physiol. 2018 02 01; 314(2):F280-F292. 
- 
								Failure to Target RANKL Signaling Through p38-MAPK Results in Defective Osteoclastogenesis in the Microphthalmia Cloudy-Eyed Mutant. J Cell Physiol. 2016 Mar; 231(3):630-40. 
- 
								May the fibrosis be with you: Is discoidin domain receptor 2 the receptor we have been looking for? J Mol Cell Cardiol. 2016 Feb; 91:201-3. 
- 
								Activation of p38 Mitogen-Activated Protein Kinase in Gaucher's Disease. PLoS One. 2015; 10(8):e0136633. 
- 
								Deubiquitinating enzyme CYLD mediates pressure overload-induced cardiac maladaptive remodeling and dysfunction via downregulating Nrf2. J Mol Cell Cardiol. 2015 Jul; 84:143-53. 
- 
								Metformin treatment in the period after stroke prevents nitrative stress and restores angiogenic signaling in the brain in diabetes. Diabetes. 2015 May; 64(5):1804-17. 
- 
								DUSP1 phosphatase regulates the proinflammatory milieu in head and neck squamous cell carcinoma. Cancer Res. 2014 Dec 15; 74(24):7191-7. 
- 
								An acetylcholinesterase inhibitor, eserine, induces long-term depression at CA3-CA1 synapses in the hippocampus of adult rats. J Neurophysiol. 2014 Nov 15; 112(10):2388-97.