p38 Mitogen-Activated Protein Kinases

"p38 Mitogen-Activated Protein Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A mitogen-activated protein kinase subfamily that regulates a variety of cellular processes including CELL GROWTH PROCESSES; CELL DIFFERENTIATION; APOPTOSIS; and cellular responses to INFLAMMATION. The P38 MAP kinases are regulated by CYTOKINE RECEPTORS and can be activated in response to bacterial pathogens.

Descriptor ID	D048051
MeSH Number(s)	D08.811.913.696.620.682.700.567.843 D12.644.360.450.835 D12.776.476.450.835
Concept/Terms	p38 Mitogen-Activated Protein Kinases p38 Mitogen-Activated Protein Kinases p38 Mitogen Activated Protein Kinases p38 MAP Kinase MAP Kinase, p38 p38 MAPK MAPK, p38 p38 SAPK Mitogen-Activated Protein Kinase p38 Mitogen Activated Protein Kinase p38 p38 Protein Kinase Protein Kinase, p38

Below are MeSH descriptors whose meaning is more general than "p38 Mitogen-Activated Protein Kinases".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Transferases [D08.811.913]
Phosphotransferases [D08.811.913.696]
Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
Protein Kinases [D08.811.913.696.620.682]
Protein-Serine-Threonine Kinases [D08.811.913.696.620.682.700]
Mitogen-Activated Protein Kinases [D08.811.913.696.620.682.700.567]
p38 Mitogen-Activated Protein Kinases [D08.811.913.696.620.682.700.567.843]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Mitogen-Activated Protein Kinases [D12.644.360.450]
p38 Mitogen-Activated Protein Kinases [D12.644.360.450.835]
Proteins [D12.776]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Mitogen-Activated Protein Kinases [D12.776.476.450]
p38 Mitogen-Activated Protein Kinases [D12.776.476.450.835]

Below are MeSH descriptors whose meaning is related to "p38 Mitogen-Activated Protein Kinases".

Below are MeSH descriptors whose meaning is more specific than "p38 Mitogen-Activated Protein Kinases".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "p38 Mitogen-Activated Protein Kinases" by people in this website by year, and whether "p38 Mitogen-Activated Protein Kinases" was a major or minor topic of these publications.

Bar chart showing 86 publications over 24 distinct years, with a maximum of 7 publications in 2005 and 2007 and 2009 and 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	1	1
1997	0	1	1
1998	0	4	4
1999	0	2	2
2000	0	4	4
2001	0	4	4
2002	0	4	4
2003	0	1	1
2004	1	3	4
2005	3	4	7
2006	2	3	5
2007	4	3	7
2008	0	4	4
2009	2	5	7
2010	1	1	2
2011	3	3	6
2012	2	3	5
2013	3	4	7
2014	1	3	4
2015	1	1	2
2016	1	1	2
2017	0	1	1
2021	0	1	1
2022	0	1	1

Below are the most recent publications written about "p38 Mitogen-Activated Protein Kinases" by people in Profiles.

Lin H, Dixon SG, Hu W, Hamlett ED, Jin J, Ergul A, Wang GY. p38 MAPK Is a Major Regulator of Amyloid Beta-Induced IL-6 Expression in Human Microglia. Mol Neurobiol. 2022 Sep; 59(9):5284-5298.

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Carver W, Fix E, Fix C, Fan D, Chakrabarti M, Azhar M. Effects of emodin, a plant-derived anthraquinone, on TGF-ß1-induced cardiac fibroblast activation and function. J Cell Physiol. 2021 11; 236(11):7440-7449.

View in: PubMed
Lee HW, Arif E, Altintas MM, Quick K, Maheshwari S, Plezia A, Mahmood A, Reiser J, Nihalani D, Gupta V. High-content screening assay-based discovery of paullones as novel podocyte-protective agents. Am J Physiol Renal Physiol. 2018 02 01; 314(2):F280-F292.

View in: PubMed
Carey HA, Bronisz A, Cabrera J, Hildreth BE, Cuitiño M, Fu Q, Ahmad A, Toribio RE, Ostrowski MC, Sharma SM. Failure to Target RANKL Signaling Through p38-MAPK Results in Defective Osteoclastogenesis in the Microphthalmia Cloudy-Eyed Mutant. J Cell Physiol. 2016 Mar; 231(3):630-40.

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DeLeon-Pennell KY. May the fibrosis be with you: Is discoidin domain receptor 2 the receptor we have been looking for? J Mol Cell Cardiol. 2016 Feb; 91:201-3.

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Kitatani K, Wada M, Perry D, Usui T, Sun Y, Obeid LM, Yaegashi N, Grabowski GA, Hannun YA. Activation of p38 Mitogen-Activated Protein Kinase in Gaucher's Disease. PLoS One. 2015; 10(8):e0136633.

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Wang H, Lai Y, Mathis BJ, Wang W, Li S, Qu C, Li B, Shao L, Song H, Janicki JS, Sun SC, Wang XL, Tang D, Cui T. Deubiquitinating enzyme CYLD mediates pressure overload-induced cardiac maladaptive remodeling and dysfunction via downregulating Nrf2. J Mol Cell Cardiol. 2015 Jul; 84:143-53.

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Abdelsaid M, Prakash R, Li W, Coucha M, Hafez S, Johnson MH, Fagan SC, Ergul A. Metformin treatment in the period after stroke prevents nitrative stress and restores angiogenic signaling in the brain in diabetes. Diabetes. 2015 May; 64(5):1804-17.

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Zhang X, Hyer JM, Yu H, D'Silva NJ, Kirkwood KL. DUSP1 phosphatase regulates the proinflammatory milieu in head and neck squamous cell carcinoma. Cancer Res. 2014 Dec 15; 74(24):7191-7.

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Kivell B, Uzelac Z, Sundaramurthy S, Rajamanickam J, Ewald A, Chefer V, Jaligam V, Bolan E, Simonson B, Annamalai B, Mannangatti P, Prisinzano TE, Gomes I, Devi LA, Jayanthi LD, Sitte HH, Ramamoorthy S, Shippenberg TS. Salvinorin A regulates dopamine transporter function via a kappa opioid receptor and ERK1/2-dependent mechanism. Neuropharmacology. 2014 Nov; 86:228-40.

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