"Fibronectins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Glycoproteins found on the surfaces of cells, particularly in fibrillar structures. The proteins are lost or reduced when these cells undergo viral or chemical transformation. They are highly susceptible to proteolysis and are substrates for activated blood coagulation factor VIII. The forms present in plasma are called cold-insoluble globulins.
| Descriptor ID |
D005353
|
| MeSH Number(s) |
D12.776.377.715.390 D12.776.395.550.350 D12.776.543.550.350 D12.776.860.300.450
|
| Concept/Terms |
Fibronectins- Fibronectins
- Opsonic alpha(2)SB Glycoprotein
- Opsonic Glycoprotein
- Glycoprotein, Opsonic
- LETS Proteins
- Proteins, LETS
- alpha 2-Surface Binding Glycoprotein
- alpha 2 Surface Binding Glycoprotein
- Fibronectin
- Cold-Insoluble Globulins
- Cold Insoluble Globulins
- Globulins, Cold-Insoluble
|
Below are MeSH descriptors whose meaning is more general than "Fibronectins".
Below are MeSH descriptors whose meaning is more specific than "Fibronectins".
This graph shows the total number of publications written about "Fibronectins" by people in this website by year, and whether "Fibronectins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 1 | 1 |
| 1994 | 1 | 0 | 1 |
| 1995 | 1 | 1 | 2 |
| 1996 | 0 | 5 | 5 |
| 1997 | 0 | 2 | 2 |
| 1998 | 0 | 1 | 1 |
| 1999 | 1 | 1 | 2 |
| 2000 | 3 | 1 | 4 |
| 2001 | 2 | 1 | 3 |
| 2002 | 1 | 2 | 3 |
| 2003 | 1 | 3 | 4 |
| 2004 | 3 | 1 | 4 |
| 2005 | 2 | 4 | 6 |
| 2006 | 1 | 6 | 7 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 1 | 2 |
| 2009 | 1 | 5 | 6 |
| 2010 | 1 | 2 | 3 |
| 2012 | 1 | 3 | 4 |
| 2013 | 1 | 4 | 5 |
| 2014 | 1 | 2 | 3 |
| 2015 | 0 | 2 | 2 |
| 2016 | 2 | 1 | 3 |
| 2017 | 0 | 2 | 2 |
| 2018 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Fibronectins" by people in Profiles.
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Fibronectin extra domain A as a drug delivery targeting epitope for rheumatoid arthritis. Adv Rheumatol. 2022 05 27; 62(1):17.
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Elevated Fibronectin Levels in Profibrotic CD14+ Monocytes and CD14+ Macrophages in Systemic Sclerosis. Front Immunol. 2021; 12:642891.
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Targeting lysyl oxidase (LOX) overcomes chemotherapy resistance in triple negative breast cancer. Nat Commun. 2020 05 15; 11(1):2416.
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Sparstolonin B (SsnB) attenuates liver fibrosis via a parallel conjugate pathway involving P53-P21 axis, TGF-beta signaling and focal adhesion that is TLR4 dependent. Eur J Pharmacol. 2018 Dec 15; 841:33-48.
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Reduced microRNA-503 expression augments lung fibroblast VEGF production in chronic obstructive pulmonary disease. PLoS One. 2017; 12(9):e0184039.
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Optimization of a murine and human tissue model to recapitulate dermal and pulmonary features of systemic sclerosis. PLoS One. 2017; 12(6):e0179917.
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Constitutive Association of Tie1 and Tie2 with Endothelial Integrins is Functionally Modulated by Angiopoietin-1 and Fibronectin. PLoS One. 2016; 11(10):e0163732.
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ATX-LPA1 axis contributes to proliferation of chondrocytes by regulating fibronectin assembly leading to proper cartilage formation. Sci Rep. 2016 Mar 23; 6:23433.
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Endothelial Cells Expressing Endothelial and Mesenchymal Cell Gene Products in Lung Tissue From Patients With Systemic Sclerosis-Associated Interstitial Lung Disease. Arthritis Rheumatol. 2016 Jan; 68(1):210-7.
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Nanometer-sized extracellular matrix coating on polymer-based scaffold for tissue engineering applications. J Biomed Mater Res A. 2016 Jan; 104(1):94-103.