Fibronectins

"Fibronectins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Glycoproteins found on the surfaces of cells, particularly in fibrillar structures. The proteins are lost or reduced when these cells undergo viral or chemical transformation. They are highly susceptible to proteolysis and are substrates for activated blood coagulation factor VIII. The forms present in plasma are called cold-insoluble globulins.

Descriptor ID	D005353
MeSH Number(s)	D12.776.377.715.390 D12.776.395.550.350 D12.776.543.550.350 D12.776.860.300.450
Concept/Terms	Fibronectins Fibronectins Opsonic alpha(2)SB Glycoprotein Opsonic Glycoprotein Glycoprotein, Opsonic LETS Proteins Proteins, LETS alpha 2-Surface Binding Glycoprotein alpha 2 Surface Binding Glycoprotein Fibronectin Cold-Insoluble Globulins Cold Insoluble Globulins Globulins, Cold-Insoluble

Below are MeSH descriptors whose meaning is more general than "Fibronectins".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Globulins [D12.776.377]
Serum Globulins [D12.776.377.715]
Fibronectins [D12.776.377.715.390]
Glycoproteins [D12.776.395]
Membrane Glycoproteins [D12.776.395.550]
Fibronectins [D12.776.395.550.350]
Membrane Proteins [D12.776.543]
Membrane Glycoproteins [D12.776.543.550]
Fibronectins [D12.776.543.550.350]
Scleroproteins [D12.776.860]
Extracellular Matrix Proteins [D12.776.860.300]
Fibronectins [D12.776.860.300.450]

Below are MeSH descriptors whose meaning is related to "Fibronectins".

Below are MeSH descriptors whose meaning is more specific than "Fibronectins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Fibronectins" by people in this website by year, and whether "Fibronectins" was a major or minor topic of these publications.

Bar chart showing 75 publications over 28 distinct years, with a maximum of 6 publications in 2005 and 2006

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1993	0	1	1
1994	1	0	1
1995	1	1	2
1996	0	5	5
1997	0	2	2
1998	0	1	1
1999	1	1	2
2000	3	1	4
2001	1	1	2
2002	0	3	3
2003	1	2	3
2004	3	1	4
2005	2	4	6
2006	0	6	6
2007	0	1	1
2008	1	1	2
2009	1	4	5
2010	1	2	3
2012	0	3	3
2013	1	4	5
2014	1	2	3
2015	0	2	2
2016	2	1	3
2017	0	2	2
2018	0	1	1
2020	0	1	1
2021	1	0	1
2022	0	1	1

Below are the most recent publications written about "Fibronectins" by people in Profiles.

Sun VZ, Melim TL, Mitra S, Erickson JE, Bryant SH, Farnham A, Westmoreland S, Knight H, Zhang L, Ritacco W, Homan K, Benatuil L, Sterman AJS, Goodearl AD. Fibronectin extra domain A as a drug delivery targeting epitope for rheumatoid arthritis. Adv Rheumatol. 2022 05 27; 62(1):17.

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Rudnik M, Hukara A, Kocherova I, Jordan S, Schniering J, Milleret V, Ehrbar M, Klingel K, Feghali-Bostwick C, Distler O, Blyszczuk P, Kania G. Elevated Fibronectin Levels in Profibrotic CD14+ Monocytes and CD14+ Macrophages in Systemic Sclerosis. Front Immunol. 2021; 12:642891.

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Saatci O, Kaymak A, Raza U, Ersan PG, Akbulut O, Banister CE, Sikirzhytski V, Tokat UM, Aykut G, Ansari SA, Dogan HT, Dogan M, Jandaghi P, Isik A, Gundogdu F, Kosemehmetoglu K, Dizdar O, Aksoy S, Akyol A, Uner A, Buckhaults PJ, Riazalhosseini Y, Sahin O. Targeting lysyl oxidase (LOX) overcomes chemotherapy resistance in triple negative breast cancer. Nat Commun. 2020 05 15; 11(1):2416.

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Dattaroy D, Seth RK, Sarkar S, Kimono D, Albadrani M, Chandrashekaran V, Hasson FA, Singh UP, Fan D, Nagarkatti M, Nagarkatti P, Diehl AM, Chatterjee S. Sparstolonin B (SsnB) attenuates liver fibrosis via a parallel conjugate pathway involving P53-P21 axis, TGF-beta signaling and focal adhesion that is TLR4 dependent. Eur J Pharmacol. 2018 Dec 15; 841:33-48.

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Ikari J, Nelson AJ, Obaid J, Giron-Martinez A, Ikari K, Makino F, Iwasawa S, Gunji Y, Farid M, Wang X, Basma H, Demeo D, Feghali-Bostwick C, Holz O, Rabe K, Liu X, Rennard SI. Reduced microRNA-503 expression augments lung fibroblast VEGF production in chronic obstructive pulmonary disease. PLoS One. 2017; 12(9):e0184039.

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Watanabe T, Nishimoto T, Mlakar L, Heywood J, Malaab M, Hoffman S, Feghali-Bostwick C. Optimization of a murine and human tissue model to recapitulate dermal and pulmonary features of systemic sclerosis. PLoS One. 2017; 12(6):e0179917.

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Dalton AC, Shlamkovitch T, Papo N, Barton WA. Constitutive Association of Tie1 and Tie2 with Endothelial Integrins is Functionally Modulated by Angiopoietin-1 and Fibronectin. PLoS One. 2016; 11(10):e0163732.

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Nishioka T, Arima N, Kano K, Hama K, Itai E, Yukiura H, Kise R, Inoue A, Kim SH, Solnica-Krezel L, Moolenaar WH, Chun J, Aoki J. ATX-LPA1 axis contributes to proliferation of chondrocytes by regulating fibronectin assembly leading to proper cartilage formation. Sci Rep. 2016 Mar 23; 6:23433.

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Mendoza FA, Piera-Velazquez S, Farber JL, Feghali-Bostwick C, Jiménez SA. Endothelial Cells Expressing Endothelial and Mesenchymal Cell Gene Products in Lung Tissue From Patients With Systemic Sclerosis-Associated Interstitial Lung Disease. Arthritis Rheumatol. 2016 Jan; 68(1):210-7.

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Uchida N, Sivaraman S, Amoroso NJ, Wagner WR, Nishiguchi A, Matsusaki M, Akashi M, Nagatomi J. Nanometer-sized extracellular matrix coating on polymer-based scaffold for tissue engineering applications. J Biomed Mater Res A. 2016 Jan; 104(1):94-103.

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