Shc Signaling Adaptor Proteins
"Shc Signaling Adaptor Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of signaling adaptor proteins that contain SRC HOMOLOGY DOMAINS. Many members of this family are involved in transmitting signals from CELL SURFACE RECEPTORS to MITOGEN-ACTIVATED PROTEIN KINASES.
| Descriptor ID |
D055765
|
| MeSH Number(s) |
D12.644.360.024.330 D12.776.157.057.162 D12.776.476.024.424
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Shc Signaling Adaptor Proteins".
Below are MeSH descriptors whose meaning is more specific than "Shc Signaling Adaptor Proteins".
This graph shows the total number of publications written about "Shc Signaling Adaptor Proteins" by people in this website by year, and whether "Shc Signaling Adaptor Proteins" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1996 | 0 | 2 | 2 |
| 1997 | 0 | 2 | 2 |
| 1998 | 0 | 4 | 4 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 3 | 3 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2017 | 2 | 0 | 2 |
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Below are the most recent publications written about "Shc Signaling Adaptor Proteins" by people in Profiles.
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Wills MKB, Lau HR, Jones N. The ShcD phosphotyrosine adaptor subverts canonical EGF receptor trafficking. J Cell Sci. 2017 Sep 01; 130(17):2808-2820.
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Wills MK, Keyvani Chahi A, Lau HR, Tilak M, Guild BD, New LA, Lu P, Jacquet K, Meakin SO, Bisson N, Jones N. Signaling adaptor ShcD suppresses extracellular signal-regulated kinase (Erk) phosphorylation distal to the Ret and Trk neurotrophic receptors. J Biol Chem. 2017 04 07; 292(14):5748-5759.
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Wills MK, Tong J, Tremblay SL, Moran MF, Jones N. The ShcD signaling adaptor facilitates ligand-independent phosphorylation of the EGF receptor. Mol Biol Cell. 2014 Mar; 25(6):739-52.
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Wills MK, Jones N. Teaching an old dogma new tricks: twenty years of Shc adaptor signalling. Biochem J. 2012 Oct 01; 447(1):1-16.
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Hawley SP, Wills MK, Rabalski AJ, Bendall AJ, Jones N. Expression patterns of ShcD and Shc family adaptor proteins during mouse embryonic development. Dev Dyn. 2011 Jan; 240(1):221-31.
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Rorie CJ, Thomas VD, Chen P, Pierce HH, O'Bryan JP, Weissman BE. The Ews/Fli-1 fusion gene switches the differentiation program of neuroblastomas to Ewing sarcoma/peripheral primitive neuroectodermal tumors. Cancer Res. 2004 Feb 15; 64(4):1266-77.
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Mukhin YV, Garnovsky EA, Ullian ME, Garnovskaya MN. Bradykinin B2 receptor activates extracellular signal-regulated protein kinase in mIMCD-3 cells via epidermal growth factor receptor transactivation. J Pharmacol Exp Ther. 2003 Mar; 304(3):968-77.
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Meyer HH, Wang Y, Warren G. Direct binding of ubiquitin conjugates by the mammalian p97 adaptor complexes, p47 and Ufd1-Npl4. EMBO J. 2002 Nov 01; 21(21):5645-52.
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Weng LP, Brown JL, Baker KM, Ostrowski MC, Eng C. PTEN blocks insulin-mediated ETS-2 phosphorylation through MAP kinase, independently of the phosphoinositide 3-kinase pathway. Hum Mol Genet. 2002 Jul 15; 11(15):1687-96.
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O'Bryan JP. Determining involvement of Shc proteins in signaling pathways. Methods Enzymol. 2001; 333:3-15.