bcl-Associated Death Protein

"bcl-Associated Death Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A pro-apoptotic protein and member of the Bcl-2 protein family that is regulated by PHOSPHORYLATION. Unphosphorylated Bad protein inhibits the activity of BCL-XL PROTEIN.

Descriptor ID	D051025
MeSH Number(s)	D12.644.360.075.718.100 D12.776.476.075.718.100 D12.776.744.049
Concept/Terms	bcl-Associated Death Protein bcl-Associated Death Protein Death Protein, bcl-Associated bcl Associated Death Protein bcl2-Antagonist of Cell Death Protein bcl2 Antagonist of Cell Death Protein Bad Protein

Below are MeSH descriptors whose meaning is more general than "bcl-Associated Death Protein".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Apoptosis Regulatory Proteins [D12.644.360.075]
Proto-Oncogene Proteins c-bcl-2 [D12.644.360.075.718]
bcl-Associated Death Protein [D12.644.360.075.718.100]
Proteins [D12.776]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Apoptosis Regulatory Proteins [D12.776.476.075]
Proto-Oncogene Proteins c-bcl-2 [D12.776.476.075.718]
bcl-Associated Death Protein [D12.776.476.075.718.100]
Phosphoproteins [D12.776.744]
bcl-Associated Death Protein [D12.776.744.049]

Below are MeSH descriptors whose meaning is related to "bcl-Associated Death Protein".

Below are MeSH descriptors whose meaning is more specific than "bcl-Associated Death Protein".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "bcl-Associated Death Protein" by people in this website by year, and whether "bcl-Associated Death Protein" was a major or minor topic of these publications.

Bar chart showing 10 publications over 9 distinct years, with a maximum of 2 publications in 2002

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	2	2
2003	0	1	1
2004	0	1	1
2005	0	1	1
2006	1	0	1
2007	0	1	1
2009	0	1	1
2012	0	1	1
2013	0	1	1

Below are the most recent publications written about "bcl-Associated Death Protein" by people in Profiles.

Talwar S, Balasubramanian S, Sundaramurthy S, House R, Wilusz CJ, Kuppuswamy D, D'Silva N, Gillespie MB, Hill EG, Palanisamy V. Overexpression of RNA-binding protein CELF1 prevents apoptosis and destabilizes pro-apoptotic mRNAs in oral cancer cells. RNA Biol. 2013 Feb; 10(2):277-86.

View in: PubMed
Kausar H, Jeyabalan J, Aqil F, Chabba D, Sidana J, Singh IP, Gupta RC. Berry anthocyanidins synergistically suppress growth and invasive potential of human non-small-cell lung cancer cells. Cancer Lett. 2012 Dec 01; 325(1):54-62.

View in: PubMed
Beharry Z, Zemskova M, Mahajan S, Zhang F, Ma J, Xia Z, Lilly M, Smith CD, Kraft AS. Novel benzylidene-thiazolidine-2,4-diones inhibit Pim protein kinase activity and induce cell cycle arrest in leukemia and prostate cancer cells. Mol Cancer Ther. 2009 Jun; 8(6):1473-83.

View in: PubMed
Prueitt RL, Boersma BJ, Howe TM, Goodman JE, Thomas DD, Ying L, Pfiester CM, Yfantis HG, Cottrell JR, Lee DH, Remaley AT, Hofseth LJ, Wink DA, Ambs S. Inflammation and IGF-I activate the Akt pathway in breast cancer. Int J Cancer. 2007 Feb 15; 120(4):796-805.

View in: PubMed
Jia W, Hegde VL, Singh NP, Sisco D, Grant S, Nagarkatti M, Nagarkatti PS. Delta9-tetrahydrocannabinol-induced apoptosis in Jurkat leukemia T cells is regulated by translocation of Bad to mitochondria. Mol Cancer Res. 2006 Aug; 4(8):549-62.

View in: PubMed
Zhou H, Hou Q, Chai Y, Hsu YT. Distinct domains of Bcl-XL are involved in Bax and Bad antagonism and in apoptosis inhibition. Exp Cell Res. 2005 Oct 01; 309(2):316-28.

View in: PubMed
Aho TL, Sandholm J, Peltola KJ, Mankonen HP, Lilly M, Koskinen PJ. Pim-1 kinase promotes inactivation of the pro-apoptotic Bad protein by phosphorylating it on the Ser112 gatekeeper site. FEBS Lett. 2004 Jul 30; 571(1-3):43-9.

View in: PubMed
Yan B, Zemskova M, Holder S, Chin V, Kraft A, Koskinen PJ, Lilly M. The PIM-2 kinase phosphorylates BAD on serine 112 and reverses BAD-induced cell death. J Biol Chem. 2003 Nov 14; 278(46):45358-67.

View in: PubMed
Datta SR, Ranger AM, Lin MZ, Sturgill JF, Ma YC, Cowan CW, Dikkes P, Korsmeyer SJ, Greenberg ME. Survival factor-mediated BAD phosphorylation raises the mitochondrial threshold for apoptosis. Dev Cell. 2002 Nov; 3(5):631-43.

View in: PubMed
Ghatak S, Misra S, Toole BP. Hyaluronan oligosaccharides inhibit anchorage-independent growth of tumor cells by suppressing the phosphoinositide 3-kinase/Akt cell survival pathway. J Biol Chem. 2002 Oct 11; 277(41):38013-20.

View in: PubMed

People

Explore

Similar Concepts

Top Journals