bcl-Associated Death Protein
"bcl-Associated Death Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A pro-apoptotic protein and member of the Bcl-2 protein family that is regulated by PHOSPHORYLATION. Unphosphorylated Bad protein inhibits the activity of BCL-XL PROTEIN.
| Descriptor ID |
D051025
|
| MeSH Number(s) |
D12.644.360.075.718.100 D12.776.476.075.718.100 D12.776.744.049
|
| Concept/Terms |
bcl-Associated Death Protein- bcl-Associated Death Protein
- Death Protein, bcl-Associated
- bcl Associated Death Protein
- bcl2-Antagonist of Cell Death Protein
- bcl2 Antagonist of Cell Death Protein
- Bad Protein
|
Below are MeSH descriptors whose meaning is more general than "bcl-Associated Death Protein".
Below are MeSH descriptors whose meaning is more specific than "bcl-Associated Death Protein".
This graph shows the total number of publications written about "bcl-Associated Death Protein" by people in this website by year, and whether "bcl-Associated Death Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 2 | 2 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "bcl-Associated Death Protein" by people in Profiles.
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Overexpression of RNA-binding protein CELF1 prevents apoptosis and destabilizes pro-apoptotic mRNAs in oral cancer cells. RNA Biol. 2013 Feb; 10(2):277-86.
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Berry anthocyanidins synergistically suppress growth and invasive potential of human non-small-cell lung cancer cells. Cancer Lett. 2012 Dec 01; 325(1):54-62.
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Novel benzylidene-thiazolidine-2,4-diones inhibit Pim protein kinase activity and induce cell cycle arrest in leukemia and prostate cancer cells. Mol Cancer Ther. 2009 Jun; 8(6):1473-83.
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Inflammation and IGF-I activate the Akt pathway in breast cancer. Int J Cancer. 2007 Feb 15; 120(4):796-805.
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Delta9-tetrahydrocannabinol-induced apoptosis in Jurkat leukemia T cells is regulated by translocation of Bad to mitochondria. Mol Cancer Res. 2006 Aug; 4(8):549-62.
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Distinct domains of Bcl-XL are involved in Bax and Bad antagonism and in apoptosis inhibition. Exp Cell Res. 2005 Oct 01; 309(2):316-28.
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Kallikrein/kinin protects against myocardial apoptosis after ischemia/reperfusion via Akt-glycogen synthase kinase-3 and Akt-Bad.14-3-3 signaling pathways. J Biol Chem. 2005 Mar 04; 280(9):8022-30.
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Pim-1 kinase promotes inactivation of the pro-apoptotic Bad protein by phosphorylating it on the Ser112 gatekeeper site. FEBS Lett. 2004 Jul 30; 571(1-3):43-9.
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The PIM-2 kinase phosphorylates BAD on serine 112 and reverses BAD-induced cell death. J Biol Chem. 2003 Nov 14; 278(46):45358-67.
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Hyaluronan oligosaccharides inhibit anchorage-independent growth of tumor cells by suppressing the phosphoinositide 3-kinase/Akt cell survival pathway. J Biol Chem. 2002 Oct 11; 277(41):38013-20.