Frizzled Receptors

"Frizzled Receptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A family of seven-pass transmembrane cell-surface proteins that combines with LOW DENSITY LIPROTEIN RECEPTOR-RELATED PROTEIN-5 or LOW DENSITY LIPROTEIN RECEPTOR-RELATED PROTEIN-5 to form receptors for WNT PROTEINS. Frizzled receptors often couple with HETEROTRIMERIC G PROTEINS and regulate the WNT SIGNALING PATHWAY.

Descriptor ID	D051157
MeSH Number(s)	D12.776.543.750.695.017 D12.776.543.750.850.500
Concept/Terms	Frizzled Receptors Frizzled Receptors Frizzled Receptor Receptor, Frizzled Receptors, Frizzled Frizzled Proteins

Below are MeSH descriptors whose meaning is more general than "Frizzled Receptors".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptors, G-Protein-Coupled [D12.776.543.750.695]
Frizzled Receptors [D12.776.543.750.695.017]
Receptors, Wnt [D12.776.543.750.850]
Frizzled Receptors [D12.776.543.750.850.500]

Below are MeSH descriptors whose meaning is related to "Frizzled Receptors".

Below are MeSH descriptors whose meaning is more specific than "Frizzled Receptors".

Frizzled Receptors
Smoothened Receptor

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Frizzled Receptors" by people in this website by year, and whether "Frizzled Receptors" was a major or minor topic of these publications.

Bar chart showing 6 publications over 5 distinct years, with a maximum of 2 publications in 2009

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2008	1	0	1
2009	1	1	2
2011	1	0	1
2013	1	0	1
2017	1	0	1

Below are the most recent publications written about "Frizzled Receptors" by people in Profiles.

Peterson YK, Nasarre P, Bonilla IV, Hilliard E, Samples J, Morinelli TA, Hill EG, Klauber-DeMore N. Frizzled-5: a high affinity receptor for secreted frizzled-related protein-2 activation of nuclear factor of activated T-cells c3 signaling to promote angiogenesis. Angiogenesis. 2017 Nov; 20(4):615-628.

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Lu J, Zhang S, Nakano H, Simmons DG, Wang S, Kong S, Wang Q, Shen L, Tu Z, Wang W, Wang B, Wang H, Wang Y, van Es JH, Clevers H, Leone G, Cross JC, Wang H. A positive feedback loop involving Gcm1 and Fzd5 directs chorionic branching morphogenesis in the placenta. PLoS Biol. 2013; 11(4):e1001536.

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Paes KT, Wang E, Henze K, Vogel P, Read R, Suwanichkul A, Kirkpatrick LL, Potter D, Newhouse MM, Rice DS. Frizzled 4 is required for retinal angiogenesis and maintenance of the blood-retina barrier. Invest Ophthalmol Vis Sci. 2011 Aug 16; 52(9):6452-61.

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Shi M, Stauffer B, Bhat R, Billiard J, Ponce-de-Leon H, Seestaller-Wehr L, Fukayama S, Mangine A, Moran R, Krishnamurthy G, Bodine P, Gopalsamy A. Identification of iminooxothiazolidines as secreted frizzled related protein-1 inhibitors. Bioorg Med Chem Lett. 2009 Nov 15; 19(22):6337-9.

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Kim JD, Chun HS, Kim SH, Kim HS, Kim YS, Kim MJ, Shin J, Rhee M, Yeo SY, Huh TL. Normal forebrain development may require continual Wnt antagonism until mid-somitogenesis in zebrafish. Biochem Biophys Res Commun. 2009 Apr 17; 381(4):717-21.

View in: PubMed
Kim S, Kim SH, Kim H, Chung AY, Cha YI, Kim CH, Huh TL, Park HC. Frizzled 8a function is required for oligodendrocyte development in the zebrafish spinal cord. Dev Dyn. 2008 Nov; 237(11):3324-31.

View in: PubMed

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