"Frizzled Receptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of seven-pass transmembrane cell-surface proteins that combines with LOW DENSITY LIPROTEIN RECEPTOR-RELATED PROTEIN-5 or LOW DENSITY LIPROTEIN RECEPTOR-RELATED PROTEIN-5 to form receptors for WNT PROTEINS. Frizzled receptors often couple with HETEROTRIMERIC G PROTEINS and regulate the WNT SIGNALING PATHWAY.
| Descriptor ID |
D051157
|
| MeSH Number(s) |
D12.776.543.750.695.017 D12.776.543.750.850.500
|
| Concept/Terms |
Frizzled Receptors- Frizzled Receptors
- Frizzled Receptor
- Receptor, Frizzled
- Receptors, Frizzled
- Frizzled Proteins
|
Below are MeSH descriptors whose meaning is more general than "Frizzled Receptors".
Below are MeSH descriptors whose meaning is more specific than "Frizzled Receptors".
This graph shows the total number of publications written about "Frizzled Receptors" by people in this website by year, and whether "Frizzled Receptors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 1 | 2 |
| 2011 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Frizzled Receptors" by people in Profiles.
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Frizzled-5: a high affinity receptor for secreted frizzled-related protein-2 activation of nuclear factor of activated T-cells c3 signaling to promote angiogenesis. Angiogenesis. 2017 Nov; 20(4):615-628.
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A positive feedback loop involving Gcm1 and Fzd5 directs chorionic branching morphogenesis in the placenta. PLoS Biol. 2013; 11(4):e1001536.
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Frizzled 4 is required for retinal angiogenesis and maintenance of the blood-retina barrier. Invest Ophthalmol Vis Sci. 2011 Aug 16; 52(9):6452-61.
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Identification of iminooxothiazolidines as secreted frizzled related protein-1 inhibitors. Bioorg Med Chem Lett. 2009 Nov 15; 19(22):6337-9.
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Normal forebrain development may require continual Wnt antagonism until mid-somitogenesis in zebrafish. Biochem Biophys Res Commun. 2009 Apr 17; 381(4):717-21.
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Frizzled 8a function is required for oligodendrocyte development in the zebrafish spinal cord. Dev Dyn. 2008 Nov; 237(11):3324-31.