Interferon Regulatory Factor-1
                             
                            
                            
                                
                            
                            
                                
                            
                            
                            
                                
                                    
                                            
	"Interferon Regulatory Factor-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
	
	
		
			
			
				An interferon regulatory factor that binds upstream TRANSCRIPTIONAL REGULATORY ELEMENTS in the GENES for INTERFERON-ALPHA and INTERFERON-BETA. It functions as a transcriptional activator for the INTERFERON TYPE I genes.
    
			
			
				
				
					
						| Descriptor ID | 
										
							D050856
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						| MeSH Number(s) | 
						
							 D12.644.360.024.302.124 D12.776.157.057.050.124 D12.776.260.108.374 D12.776.260.504.124 D12.776.476.024.385.124 D12.776.930.127.374 D12.776.930.332.124 
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						| Concept/Terms | 
						
							Interferon Regulatory Factor-1- Interferon Regulatory Factor-1
 - Interferon Regulatory Factor 1
 - IRF-1 Protein
 - IRF 1 Protein
 - IREBF1 Transcription Factor
 - Transcription Factor, IREBF1
 - IREBF1 Protein
 - IRF-1 Transcription Factor
 - Factor, IRF-1 Transcription
 - IRF 1 Transcription Factor
 - Transcription Factor, IRF-1
 - ISGF1 Transcription Factor
 - Factor, ISGF1 Transcription
 - Transcription Factor, ISGF1
 - Interferon-Stimulated Gene Factor 1
 - Interferon Stimulated Gene Factor 1
 - MyD32 Protein
 
  
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				Below are MeSH descriptors whose meaning is more general than "Interferon Regulatory Factor-1".
				
			 
			
			
				Below are MeSH descriptors whose meaning is more specific than "Interferon Regulatory Factor-1".
				
			 
		 
	 
 
                                        
                                            
	
	
		
			
			
					
				This graph shows the total number of publications written about "Interferon Regulatory Factor-1" by people in this website by year, and whether "Interferon Regulatory Factor-1" was a major or minor topic of these publications. 
				
					
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		            | Year | Major Topic | Minor Topic | Total | 
|---|
| 2006 | 1 | 0 | 1 | 
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				Below are the most recent publications written about "Interferon Regulatory Factor-1" by people in Profiles.
						
					
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Interferon regulatory factor-1 gene deletion decreases glomerulonephritis in MRL/lpr mice. Eur J Immunol. 2006 May; 36(5):1296-308.