"Chymotrypsin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serine endopeptidase secreted by the pancreas as its zymogen, CHYMOTRYPSINOGEN and carried in the pancreatic juice to the duodenum where it is activated by TRYPSIN. It selectively cleaves aromatic amino acids on the carboxyl side.
| Descriptor ID |
D002918
|
| MeSH Number(s) |
D08.811.277.656.300.760.176 D08.811.277.656.959.350.176
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Chymotrypsin".
Below are MeSH descriptors whose meaning is more specific than "Chymotrypsin".
This graph shows the total number of publications written about "Chymotrypsin" by people in this website by year, and whether "Chymotrypsin" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Chymotrypsin" by people in Profiles.
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Abu-El-Haija M, Hornung L, Denson LA, Husami A, Lin TK, Matlock K, Nathan JD, Palermo JJ, Thompson T, Valencia CA, Wang X, Woo J, Zhang K, Elder D. Prevalence of abnormal glucose metabolism in pediatric acute, acute recurrent and chronic pancreatitis. PLoS One. 2018; 13(10):e0204979.
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Li H, Su M, Hamann MT, Bowling JJ, Kim HS, Jung JH. Solution structure of a sponge-derived cystine knot peptide and its notable stability. J Nat Prod. 2014 Feb 28; 77(2):304-10.
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Lancet JE, Duong VH, Winton EF, Stuart RK, Burton M, Zhang S, Cubitt C, Blaskovich MA, Wright JJ, Sebti S, Sullivan DM. A phase I clinical-pharmacodynamic study of the farnesyltransferase inhibitor tipifarnib in combination with the proteasome inhibitor bortezomib in advanced acute leukemias. Clin Cancer Res. 2011 Mar 01; 17(5):1140-6.
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Karajanagi SS, Vertegel AA, Kane RS, Dordick JS. Structure and function of enzymes adsorbed onto single-walled carbon nanotubes. Langmuir. 2004 Dec 21; 20(26):11594-9.
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McIntire WE, Schey KL, Knapp DR, Hildebrandt JD. A major G protein alpha O isoform in bovine brain is deamidated at Asn346 and Asn347, residues involved in receptor coupling. Biochemistry. 1998 Oct 20; 37(42):14651-8.
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Chao J, Schmaier A, Chen LM, Yang Z, Chao L. Kallistatin, a novel human tissue kallikrein inhibitor: levels in body fluids, blood cells, and tissues in health and disease. J Lab Clin Med. 1996 Jun; 127(6):612-20.
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Duncan R, Horne D, Strong JE, Leone G, Pon RT, Yeung MC, Lee PW. Conformational and functional analysis of the C-terminal globular head of the reovirus cell attachment protein. Virology. 1991 Jun; 182(2):810-9.
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Greenberg CS, Shuman MA. Specific binding of blood coagulation factor XIIIa to thrombin-stimulated platelets. J Biol Chem. 1984 Dec 10; 259(23):14721-7.